chrom pos ref alt rsids nearest_genes pval num_cases num_controls num_samples phenostring num_peaks phenocode gc_lambda_hundred category 6 25616225 A G rs78912080 CARMIL1 0.0 665 405082 405747 Disorders of iron metabolism 8 275.1 1.0 hematopoietic 6 32418606 A G rs2187819 BTNL2 0.0 1846 333378 335224 Celiac disease 7 557.1 1.0283 digestive 3 38009720 G A rs75495843 PLCD1 0.0 5281 400630 405911 Diseases of hair and hair follicles 5 704 1.0138 dermatologic 3 38009720 G A rs75495843 PLCD1 0.0 8833 397542 406375 Sebaceous cyst 7 706.2 1.0195 dermatologic 22 45971264 G A rs28971325 WNT7B 0.0 3488 377173 380661 Contracture of palmar fascia [Dupuytren's disease] 37 728.71 1.0138 musculoskeletal 22 45971264 G A rs28971325 WNT7B 4.9e-299 3812 377171 380983 Fasciitis 34 728.7 1.0138 musculoskeletal 22 45971264 G A rs28971325 WNT7B 2.3e-296 3688 377174 380862 Disorders of muscle, ligament, and fascia 35 728 1.0166 musculoskeletal 3 38009720 G A rs75495843 PLCD1 8.2e-284 8356 397541 405897 Diseases of sebaceous glands 6 706 1.0195 dermatologic 6 26092913 G A rs1800562 HFE 2.4e-255 2119 405080 407199 Disorders of mineral metabolism 3 275 1.0195 endocrine/metabolic 6 31368220 C T rs146683910 HLA-B 9.5e-212 617 363561 364178 Ankylosing spondylitis 5 715.2 0.97444 musculoskeletal 1 169549811 C T rs6025 F5 9.4e-207 303 404523 404826 Congenital deficiency of other clotting factors (including factor VII) 13 286.12 1.0344 hematopoietic 2 43842633 G A rs75331444 ABCG8 2.7e-189 15775 389625 405400 Cholelithiasis and cholecystitis 29 574 1.0469 digestive 2 233757337 A G rs1976391 UGT1A10,UGT1A3,UGT1A4,UGT1A5,UGT1A6,UGT1A7,UGT1A8,UGT1A9 3e-181 362 405785 406147 Disorders of bilirubin excretion 8 277.4 1.0166 endocrine/metabolic 1 169549811 C T rs6025 F5 5e-178 470 404523 404993 Congenital coagulation defects 13 286.1 1.0 hematopoietic 2 43839108 G C rs11887534 ABCG8 6.2e-177 13679 389624 403303 Cholelithiasis 19 574.1 1.0406 digestive 4 110791276 A G rs2129977 PITX2 4.6e-160 14756 379217 393973 Atrial fibrillation and flutter 44 427.2 1.0469 circulatory system 6 31284147 C T rs12189871 HLA-C 5.9e-152 2197 396508 398705 Psoriasis 6 696.4 1.0254 dermatologic 6 31284147 C T rs12189871 HLA-C 3e-151 2250 396509 398759 Psoriasis and related disorders 6 696 1.0224 dermatologic 6 32658698 G A rs9273368 HLA-DQB1 4.7e-147 2762 387081 389843 Type 1 diabetes 6 250.1 1.0138 endocrine/metabolic 6 32593593 C T rs35139284 HLA-DRB1 1.7e-145 4380 363562 367942 Rheumatoid arthritis 6 714.1 1.0224 musculoskeletal 1 169549811 C T rs6025 F5 7.9e-141 932 404524 405456 Coagulation defects 3 286 1.0 hematopoietic 6 31284147 C T rs12189871 HLA-C 1.3e-139 1679 396508 398187 Psoriasis vulgaris 4 696.41 1.0313 dermatologic 10 112998590 C T rs7903146 TCF7L2 4.7e-137 20102 387087 407189 Diabetes mellitus 58 250 1.108 endocrine/metabolic 10 112998590 C T rs7903146 TCF7L2 1.1e-134 18105 387087 405192 Type 2 diabetes 55 250.2 1.104 endocrine/metabolic 6 32593593 C T rs35139284 HLA-DRB1 1.1e-132 4842 363563 368405 Rheumatoid arthritis and other inflammatory polyarthropathies 6 714 1.0254 musculoskeletal 6 31368220 C T rs146683910 HLA-B 3.1e-126 1657 363563 365220 Other inflammatory spondylopathies 5 715 1.011 musculoskeletal 1 169549811 C T rs6025 F5 6.5e-111 3681 367909 371590 Phlebitis and thrombophlebitis of lower extremities 9 451.2 1.0054 circulatory system 1 169549811 C T rs6025 F5 6.5e-106 3952 367910 371862 Phlebitis and thrombophlebitis 9 451 1.0082 circulatory system 6 396321 C T rs12203592 IRF4 2.9e-96 11090 393357 404447 Other non-epithelial cancer of skin 37 172.2 1.0437 neoplasms 9 22102166 C T rs7859727 AL359922.1 3.4e-96 20454 374655 395109 Coronary atherosclerosis 50 411.4 1.0811 circulatory system 2 43839108 G C rs11887534 ABCG8 3.1e-93 5452 389620 395072 Cholelithiasis with other cholecystitis 8 574.12 1.0195 digestive 19 44908684 T C rs429358 APOE 1.6e-91 1001 400598 401599 Dementias 3 290.1 1.0 mental disorders 6 32619017 T G rs9271365 HLA-DQA1 3.8e-91 14783 389743 404526 Hypothyroidism 51 244 1.0848 endocrine/metabolic 6 396321 C T rs12203592 IRF4 3e-90 13612 393357 406969 Skin cancer 37 172 1.0469 neoplasms 6 32619017 T G rs9271365 HLA-DQA1 5.4e-90 14098 389745 403843 Hypothyroidism NOS 54 244.4 1.0885 endocrine/metabolic 4 110791530 T C rs1906599 PITX2 4.6e-87 24571 379214 403785 Cardiac dysrhythmias 25 427 1.0437 circulatory system 6 32536048 T C rs75802100 HLA-DRB5 1.7e-84 1339 393433 394772 Multiple sclerosis 8 335 1.0138 neurological 1 10765520 C T rs11121615 CASZ1 4.9e-79 11622 367913 379535 Varicose veins of lower extremity 28 454.1 1.0669 circulatory system 9 22103814 A G rs1333042 AL359922.1 1.9e-77 31952 374656 406608 Ischemic Heart Disease 45 411 1.104 circulatory system 19 44908822 C T rs7412 APOE 3.6e-74 35726 371440 407166 Disorders of lipoid metabolism 45 272 1.108 endocrine/metabolic 19 44908822 C T rs7412 APOE 2e-73 35652 371440 407092 Hyperlipidemia 46 272.1 1.108 endocrine/metabolic 1 10765520 C T rs11121615 CASZ1 5.1e-72 11281 367913 379194 Varicose veins 23 454 1.0635 circulatory system 10 121589148 T G rs2912774 FGFR2 6.2e-72 12790 387413 400203 Breast cancer 36 174 1.0254 neoplasms 10 121589148 T G rs2912774 FGFR2 8.6e-72 12571 200465 213036 Breast cancer [female] 37 174.1 1.0254 neoplasms 19 44908822 C T rs7412 APOE 5.5e-71 33084 371439 404523 Hypercholesterolemia 39 272.11 1.1001 endocrine/metabolic 10 121580917 GC G rs35054928 FGFR2 6.8e-71 11841 200465 212306 Malignant neoplasm of female breast 29 174.11 1.0224 neoplasms 6 32658698 G A rs9273368 HLA-DQB1 9.5e-68 473 387081 387554 Type 1 diabetes with ophthalmic manifestations 2 250.13 1.0 endocrine/metabolic 1 169549811 C T rs6025 F5 5.9e-67 16261 386242 402503 Circulatory disease NEC 7 459.9 1.0254 circulatory system 19 44908684 T C rs429358 APOE 6.4e-67 1927 400598 402525 Delirium dementia and amnestic and other cognitive disorders 5 290 1.0054 mental disorders 19 44908684 T C rs429358 APOE 4.3e-66 430 400600 401030 Alzheimer's disease 1 290.11 1.0 mental disorders 4 88124179 A G rs2199936 ABCG2 7.5e-66 3179 403457 406636 Gout 8 274.1 1.011 endocrine/metabolic 1 169549811 C T rs6025 F5 2.7e-65 16428 386242 402670 Other disorders of circulatory system 6 459 1.0254 circulatory system 6 32659200 T C rs9273386 HLA-DQB1 4.8e-64 26167 373887 400054 Asthma 37 495 1.104 respiratory 4 88124179 A G rs2199936 ABCG2 1.2e-57 3735 403459 407194 Gout and other crystal arthropathies 9 274 1.0138 endocrine/metabolic 9 22103814 A G rs1333042 AL359922.1 4.5e-55 12038 374657 386695 Myocardial infarction 21 411.2 1.0469 circulatory system 6 32333650 C T rs115378818 TSBP1 1.4e-53 4460 333378 337838 Inflammatory bowel disease and other gastroenteritis and colitis 18 555 1.0224 digestive 2 43842633 G A rs75331444 ABCG8 1.3e-51 2622 389617 392239 Calculus of bile duct 2 574.2 1.0054 digestive 4 80261400 T C rs12509595 FGF5 2.9e-49 77714 328796 406510 Hypertension 142 401 1.2626 circulatory system 6 160576086 A T rs74617384 LPA 3e-49 15490 374663 390153 Other chronic ischemic heart disease, unspecified 23 411.8 1.0601 circulatory system 2 227052367 G C rs35138315 COL4A4 8.8e-49 16235 378356 394591 Hematuria 17 593 1.0344 genitourinary 4 80261400 T C rs12509595 FGF5 1.1e-48 77465 328796 406261 Essential hypertension 146 401.1 1.2626 circulatory system 9 22099569 C A rs1537371 AL359922.1 3.6e-48 16102 374656 390758 Angina pectoris 23 411.3 1.0669 circulatory system 6 32333650 C T rs115378818 TSBP1 6.8e-45 3183 333377 336560 Ulcerative colitis 13 555.2 1.011 digestive 2 55869757 A G rs3791679 EFEMP1 1.5e-44 15932 360069 376001 Inguinal hernia 32 550.1 1.0406 digestive 6 32658525 T G rs9273364 HLA-DQB1 2.3e-44 239 387081 387320 Type 1 diabetes with ketoacidosis 5 250.11 1.0469 endocrine/metabolic 6 32658698 G A rs9273368 HLA-DQB1 2.4e-40 1330 395155 396485 Diabetic retinopathy 2 250.7 1.011 endocrine/metabolic 18 55668281 T A rs11659764 TCF4 3e-40 212 396051 396263 Corneal dystrophy 5 364.5 1.0567 sense organs 2 143551211 C G rs6717024 ARHGAP15 5.4e-40 27204 333384 360588 Diverticulosis and diverticulitis 46 562 1.0848 digestive 2 143551211 C G rs6717024 ARHGAP15 5.7e-40 27161 333384 360545 Diverticulosis 46 562.1 1.0848 digestive 6 32622860 T A rs9271579 HLA-DQA1 1.6e-37 3300 388555 391855 Nasal polyps 17 471 1.0138 respiratory 6 31346230 AC A rs36058333 HLA-B 1.7e-37 705 396507 397212 Psoriatic arthropathy 3 696.42 0.97444 dermatologic 20 19476624 A G rs4814857 SLC24A3 5.4e-37 20234 386965 407199 Cataract 22 366 1.0375 sense organs 6 32262212 TG T rs146576271 TSBP1 2.8e-36 1853 389744 391597 Thyrotoxicosis with or without goiter 5 242 1.0166 endocrine/metabolic 9 133274414 A G rs532436 ABO 4.2e-36 4478 400265 404743 Pulmonary heart disease 12 415 1.0054 circulatory system 11 32437682 G T rs4140413 WT1 2e-35 46703 360073 406776 Abdominal hernia 23 550 1.0775 digestive 8 127401060 G T rs6983267 POU5F1B 9.7e-35 5993 168999 174992 Cancer of prostate 28 185 1.0166 neoplasms 2 43842633 G A rs75331444 ABCG8 2e-34 3867 389625 393492 Other biliary tract disease 3 575 1.0027 digestive 6 396321 C T rs12203592 IRF4 2.7e-33 7688 398897 406585 Benign neoplasm of skin 9 216 1.0138 neoplasms 18 48925957 A G rs2337113 SMAD7 3.3e-33 20121 384292 404413 Benign neoplasm of colon 26 208 1.0469 neoplasms 6 32333650 C T rs115378818 TSBP1 1.1e-32 1653 333378 335031 Ileostomy status 1 559 1.011 digestive 2 43842633 G A rs75331444 ABCG8 1.7e-32 2747 389620 392367 Cholecystitis without cholelithiasis 4 574.3 1.0 digestive 6 32658698 G A rs9273368 HLA-DQB1 1.8e-31 931 384670 385601 Hypoglycemia 3 251.1 0.97444 endocrine/metabolic 6 32333650 C T rs115378818 TSBP1 6.2e-31 1737 333378 335115 Regional enteritis 10 555.1 1.0166 digestive 18 55668281 T A rs11659764 TCF4 2.4e-30 647 396051 396698 Corneal opacity and other disorders of cornea 3 364 0.97444 sense organs 16 89729609 G A rs34659644 ZNF276 5e-30 2712 393365 396077 Melanomas of skin 10 172.11 1.0027 neoplasms 7 121322110 A G rs2908007 WNT16 6.1e-30 5223 386067 391290 Fracture of radius and ulna 6 803.2 1.011 injuries & poisonings 16 89919709 C T rs1805007 AC092143.1,MC1R 2.1e-29 2680 393365 396045 Melanomas of skin, dx or hx 12 172.1 1.0027 neoplasms 6 396321 C T rs12203592 IRF4 1.2e-28 2394 404806 407200 Benign neoplasm of unspecified sites 5 229 1.0027 neoplasms 16 53769311 G A rs62048402 FTO 2.5e-27 10907 396292 407199 Overweight, obesity and other hyperalimentation 9 278 1.0601 endocrine/metabolic 16 53769662 T A rs1558902 FTO 1.4e-26 10742 396293 407035 Obesity 9 278.1 1.0601 endocrine/metabolic 6 32598621 G A rs2760985 HLA-DRB1 5.4e-26 1145 406057 407202 Polymyalgia Rheumatica 2 717 1.0 musculoskeletal 6 32698749 C T rs1794282 HLA-DQB1 2e-25 456 389744 390200 Graves' disease 5 242.1 1.0 endocrine/metabolic 11 1219991 G T rs35705950 MUC5B 2.5e-25 917 395582 396499 Postinflammatory pulmonary fibrosis 6 502 1.0 respiratory 2 43835959 G C rs115445558 ABCG5,ABCG8 2.6e-25 1505 389623 391128 Cholelithiasis with acute cholecystitis 3 574.11 1.0054 digestive 6 31401501 G T rs114892859 MICA 2e-24 15996 380141 396137 Allergy/adverse effect of penicillin 8 960.2 1.0313 injuries & poisonings 22 43928850 C T rs738408 PNPLA3 2.8e-24 2954 398276 401230 Chronic liver disease and cirrhosis 5 571 1.0 digestive 17 7668434 T G rs78378222 TP53 5.1e-24 10309 203951 214260 Uterine leiomyoma 17 218.1 1.0166 neoplasms 1 219580167 T C rs2820443 ZC3H11B 8.3e-23 3708 360063 363771 Umbilical hernia 4 550.4 1.011 digestive 9 97775520 A C rs1588635 FOXE1 1.1e-22 674 389740 390414 Nontoxic multinodular goiter 9 241.2 0.97444 endocrine/metabolic 6 31401501 G T rs114892859 MICA 1.1e-22 18309 380143 398452 Poisoning by antibiotics 6 960 1.0344 injuries & poisonings 6 160576086 A T rs74617384 LPA 1.5e-22 5159 374651 379810 Unstable angina (intermediate coronary syndrome) 5 411.1 1.0166 circulatory system 6 32706117 C T rs1794269 HLA-DQA2 3.2e-22 160 387082 387242 Type 1 diabetes with neurological manifestations 3 250.14 1.0669 endocrine/metabolic 7 121322110 A G rs2908007 WNT16 5.6e-22 8315 386070 394385 Fracture of upper limb 6 803 1.0224 injuries & poisonings 20 19476624 A G rs4814857 SLC24A3 6.2e-22 8321 386965 395286 Senile cataract 8 366.2 1.0313 sense organs 6 396321 C T rs12203592 IRF4 8.2e-22 2581 401729 404310 Actinic keratosis 6 702.1 1.0082 dermatologic 14 94378610 C T rs28929474 SERPINA1 3.6e-21 898 405781 406679 Other disorders of metabolism 4 277 0.97444 endocrine/metabolic 5 1336063 A T rs457130 CLPTM1L 5.5e-21 11176 169004 180180 Hyperplasia of prostate 24 600 1.0224 genitourinary 17 7668434 T G rs78378222 TP53 1.1e-20 10089 203951 214040 Benign neoplasm of uterus 18 218 1.0138 neoplasms 16 20381010 G A rs77924615 PDILT 4.4e-20 3175 399288 402463 Calculus of kidney 5 594.1 1.011 genitourinary 14 94378610 C T rs28929474 SERPINA1 1.2e-19 1744 373884 375628 Emphysema 7 496.1 1.0082 respiratory 6 32619234 A T rs28383311 HLA-DQA1 8.1e-19 362 402714 403076 Nodular lymphoma 7 202.21 1.0138 neoplasms 10 122456049 T C rs3750846 ARMS2 8.5e-19 2180 395156 397336 Macular degeneration (senile) of retina NOS 5 362.29 1.0027 sense organs 22 43928975 G A rs3747207 PNPLA3 1.2e-18 1687 398277 399964 Other chronic nonalcoholic liver disease 3 571.5 1.0138 digestive 10 122456049 T C rs3750846 ARMS2 1.3e-18 2183 395156 397339 Degeneration of macula and posterior pole of retina 5 362.2 1.0027 sense organs 1 155151361 G C rs6676150 DPM3 3.7e-18 5257 393413 398670 Benign neoplasm of other parts of digestive system 4 211 1.0138 neoplasms 20 62357358 T C rs1741640 LAMA5 9e-18 7373 385685 393058 Anal and rectal polyp 4 565.1 1.0138 digestive 9 4999303 A G rs1327494 JAK2 9.5e-18 388 399421 399809 Polycythemia vera 2 200.1 1.0082 neoplasms 19 44908684 T C rs429358 APOE 1e-17 201 400598 400799 Vascular dementia 1 290.16 1.0534 mental disorders 4 110799663 A G rs13121924 PITX2 1e-17 3086 403887 406973 Appendiceal conditions 5 540 1.0 digestive 9 5070227 ATTATC A rs56241661 JAK2 1.2e-17 992 402716 403708 Myeloproliferative disease 3 200 1.0 neoplasms 1 169238941 C T rs2227246 NME7 2.5e-17 4617 401760 406377 Swelling of limb 3 771.1 1.0138 symptoms 20 35416964 C T rs62210593 UQCC1 5.7e-17 15715 364266 379981 Unspecified monoarthritis 5 716.2 1.0601 musculoskeletal 11 32458261 G A rs11031796 WT1 7.1e-17 26993 360063 387056 Diaphragmatic hernia 18 550.2 1.0775 digestive 11 5225923 G A rs34451549 HBB 8.4e-17 57 388395 388452 Other hemoglobinopathies 33 282.8 1.0027 hematopoietic 4 99318162 T C rs1229984 ADH1B 1.3e-16 5315 377725 383040 Substance addiction and disorders 2 316 1.0138 mental disorders 4 110810958 G A rs3866831 PITX2 1.6e-16 2893 403887 406780 Appendicitis 5 540.1 1.0 digestive 2 20678646 T C rs3072 GDF7 1.6e-16 11787 207910 219697 Genital prolapse 9 618 1.0283 genitourinary 1 165774286 A G rs2790049 TMCO1 1.7e-16 4428 396053 400481 Glaucoma 11 365 1.0166 sense organs 2 43835959 G C rs115445558 ABCG5,ABCG8 2.2e-16 1407 389622 391029 Other disorders of gallbladder 1 575.7 1.0027 digestive 15 49534569 C CAG rs34260484 FAM227B 2.3e-16 1105 389741 390846 Nontoxic nodular goiter 6 241 1.0 endocrine/metabolic 11 92874700 C T rs10765568 FAT3 4.4e-16 3244 396051 399295 Retinal detachments and defects 4 361 1.0054 sense organs 6 32454414 G A rs2097442 HLA-DRA 5.2e-16 1802 402713 404515 Non-Hodgkins lymphoma 4 202.2 1.0138 neoplasms 1 169549811 C T rs6025 F5 5.4e-16 6241 399888 406129 Lipoma 6 214 1.0082 neoplasms 4 99318162 T C rs1229984 ADH1B 7.5e-16 12791 377727 390518 Alcohol-related disorders 3 317 1.0313 mental disorders 21 36446573 A G rs2776288 CLDN14 1.2e-15 6391 399288 405679 Urinary calculus 10 594 1.0254 genitourinary 16 53880018 G A rs11076004 FTO 1.6e-15 2714 397693 400407 Unspecified diffuse connective tissue disease 5 709.7 1.0082 dermatologic 9 22124745 C G rs4977575 AL359922.1 1.8e-15 2580 398705 401285 Peripheral vascular disease, unspecified 2 443.9 1.0054 circulatory system 5 1292868 C A rs2853672 TERT 1.8e-15 3081 401726 404807 Seborrheic keratosis 3 702.2 1.0027 dermatologic 6 31403207 C T rs116135464 MICA 2e-15 481 397602 398083 Uveitis, noninfectious or NOS 4 371.1 0.97444 sense organs 3 128356555 T G rs1735546 EEFSEC 2e-15 7876 207566 215442 Polyp of corpus uteri 3 622.1 1.0 genitourinary 20 35417437 T C rs6060402 UQCC1 2.5e-15 15358 389780 405138 Internal derangement of knee 8 835 1.0313 injuries & poisonings 10 113057250 A C rs11196211 TCF7L2 3.2e-15 986 387082 388068 Type 2 diabetes with ophthalmic manifestations 4 250.23 1.0 endocrine/metabolic 10 121589148 T G rs2912774 FGFR2 6.9e-15 2404 199511 201915 Acquired absence of breast 6 175 1.0 neoplasms 6 32615435 A G rs28383221 HLA-DQA1 8.1e-15 539 400947 401486 Sarcoidosis 11 697 0.97444 dermatologic 1 169465789 C T rs2678166 SLC19A2 1e-14 6024 377183 383207 Other disorders of soft tissues 3 729 1.0138 musculoskeletal 1 169465789 C T rs2678166 SLC19A2 1.1e-14 385 404524 404909 Other and unspecified coagulation defects 4 286.7 1.0 hematopoietic 6 32706117 C T rs1794269 HLA-DQA2 1.5e-14 76 387082 387158 Type 1 diabetes with renal manifestations 4 250.12 1.0375 endocrine/metabolic 2 217281820 T A rs12694411 TNP1 1.6e-14 12530 392377 404907 Other peripheral nerve disorders 8 351 1.0406 neurological 4 110810780 T C rs6533530 PITX2 1.6e-14 2599 403886 406485 Acute appendicitis 1 540.11 1.0054 digestive 11 5225923 G A rs34451549 HBB 1.9e-14 151 388395 388546 Hereditary hemolytic anemias 5 282 1.0669 hematopoietic 1 169549811 C T rs6025 F5 2e-14 4589 399888 404477 Lipoma of skin and subcutaneous tissue 2 214.1 1.011 neoplasms 6 31371067 T C rs2853986 HLA-B 3.3e-14 511 397694 398205 Sicca syndrome 6 709.2 1.0 dermatologic 2 184333408 C A rs12465214 ZNF804A 4.1e-14 9102 398100 407202 Syncope and collapse 2 788 1.0166 symptoms 8 127707639 A T rs10094872 MYC 4.3e-14 2142 403026 405168 Malignant neoplasm of bladder 6 189.21 1.0 neoplasms 6 160576086 A T rs74617384 LPA 4.7e-14 1816 404392 406208 Congenital anomalies of great vessels 3 747.13 1.011 congenital anomalies 2 43839108 G C rs11887534 ABCG8 5.4e-14 456 389621 390077 Cholesterolosis of gallbladder 2 575.6 0.97444 digestive 8 127707639 A T rs10094872 MYC 5.5e-14 2409 403027 405436 Cancer of bladder 5 189.2 1.0027 neoplasms 6 32699696 G C rs1794514 HLA-DQB1 5.7e-14 12189 388402 400591 Other anemias 7 285 1.0195 hematopoietic 9 133274084 C T rs529565 ABO 8.4e-14 23787 367911 391698 Hemorrhoids 11 455 1.0469 circulatory system 18 48922435 T C rs6507874 SMAD7 8.7e-14 4587 380932 385519 Colorectal cancer 3 153 1.011 neoplasms 15 78606661 C A rs56077333 CHRNA3 9.7e-14 10516 373881 384397 Chronic airway obstruction 6 496 1.0375 respiratory 8 127707639 A T rs10094872 MYC 2e-13 4162 403026 407188 Cancer of urinary organs (incl. kidney and bladder) 4 189 1.0027 neoplasms 7 121322110 A G rs2908007 WNT16 2e-13 3340 386073 389413 Fracture of hand or wrist 10 804 1.0027 injuries & poisonings 6 396321 C T rs12203592 IRF4 2.1e-13 5475 397054 402529 Degenerative skin conditions and other dermatoses 5 702 1.0138 dermatologic 20 35438203 G A rs143383 GDF5 2.2e-13 6671 393238 399909 Hallux valgus (Bunion) 6 735.3 1.0254 musculoskeletal 6 31466844 A G rs3131618 MICB 2.3e-13 3441 397694 401135 Diffuse diseases of connective tissue 4 709 1.011 dermatologic 19 51715646 C T rs7254072 HAS1 2.3e-13 3109 377184 380293 Ganglion and cyst of synovium, tendon, and bursa 3 727.4 1.0 musculoskeletal 6 32658263 C T rs4713570 HLA-DQB1 2.4e-13 2265 402714 404979 Cancer of other lymphoid, histiocytic tissue 3 202 1.011 neoplasms 11 30204981 G A rs11031006 FSHB 2.4e-13 14224 189126 203350 Irregular menstrual cycle/bleeding 4 626.1 1.0224 genitourinary 15 32719496 G C rs79207432 GREM1 2.5e-13 14836 385688 400524 Anal and rectal conditions 6 565 1.0195 digestive 8 8666851 T C rs11997261 CLDN23 3.9e-13 28212 378902 407114 Osteoarthrosis 21 740 1.0704 musculoskeletal 10 122456049 T C rs3750846 ARMS2 5.6e-13 3836 395156 398992 Other retinal disorders 7 362 1.0 sense organs 9 133602085 C G rs113927489 FAM163B 6.7e-13 19655 377718 397373 Tobacco use disorder 12 318 1.0775 mental disorders 6 484453 C G rs116446171 EXOC2 7.8e-13 260 406470 406730 Disorders of plasma protein metabolism 4 270.3 1.0406 endocrine/metabolic 11 30220740 T C rs74485684 FSHB 9.2e-13 9788 189132 198920 Excessive or frequent menstruation 7 626.12 1.0254 genitourinary 7 121326736 A G rs3779381 WNT16 9.4e-13 5583 399565 405148 Osteoporosis NOS 4 743.11 1.0195 musculoskeletal 2 113234797 G C rs4849183 PAX8 1e-12 1339 167469 168808 Hydrocele 5 603.1 0.97444 genitourinary 9 22124745 C G rs4977575 AL359922.1 1.3e-12 3688 398704 402392 Other specified peripheral vascular diseases 3 443.8 1.0082 circulatory system 8 142684641 C G rs2585183 PSCA 1.3e-12 3000 399774 402774 Duodenal ulcer 4 531.3 1.0 digestive 6 32236099 A G rs3130301 NOTCH4 1.4e-12 2377 400950 403327 Erythematous conditions 4 695 1.0054 dermatologic 12 114228780 G A rs10774741 TBX5 1.5e-12 8814 383299 392113 Urinary incontinence 6 599.4 1.0224 genitourinary 2 43842633 G A rs75331444 ABCG8 1.9e-12 1036 389622 390658 Other disorders of biliary tract 3 575.8 1.0 digestive 6 32112414 G C rs1269852 TNXB 2.2e-12 338 399660 399998 Systemic lupus erythematosus 3 695.42 1.0082 dermatologic 5 128014857 C T rs3749748 SLC12A2 4e-12 5494 395974 401468 Cellulitis and abscess of leg, except foot 4 681.5 1.011 dermatologic 5 128014857 C T rs3749748 SLC12A2 4.3e-12 5486 395974 401460 Cellulitis and abscess of arm/hand 3 681.3 1.011 dermatologic 12 27862568 G C rs11049206 KLHL42 4.3e-12 17598 378904 396502 Osteoarthritis; localized 12 740.1 1.0501 musculoskeletal 15 49418988 T C rs17477923 FAM227B 4.4e-12 599 389743 390342 Simple and unspecified goiter 1 240 0.97444 endocrine/metabolic 6 396321 C T rs12203592 IRF4 4.7e-12 665 393366 394031 Carcinoma in situ of skin 4 172.3 0.97444 neoplasms 5 128014857 C T rs3749748 SLC12A2 6.2e-12 5449 395974 401423 Cellulitis and abscess of foot, toe 4 681.6 1.011 dermatologic 5 133089726 A G rs764634404 HSPA4 7.3e-12 5318 212197 217515 Obstetrical/birth trauma 2 665 1.0054 pregnancy complications 19 44908684 T C rs429358 APOE 7.5e-12 2178 400600 402778 Altered mental status 4 292.4 1.0027 mental disorders 19 44908684 T C rs429358 APOE 8.1e-12 4623 400600 405223 Neurological disorders 2 292 1.0054 mental disorders 1 219607456 G A rs3902972 ZC3H11B 8.6e-12 650 360062 360712 Femoral hernia 3 550.3 0.97444 digestive 6 32710135 C T rs9275563 HLA-DQA2 1.1e-11 3279 167468 170747 Disorders of penis 6 604 1.0 genitourinary 8 142698204 CTT C rs35464379 LY6K 1.2e-11 7624 376450 384074 Duodenitis 4 535.6 1.0195 digestive 10 62492218 C T rs10822013 AC024598.1 1.2e-11 1388 213273 214661 Benign neoplasm of breast 5 610.4 1.0082 genitourinary 2 20678646 T C rs3072 GDF7 1.2e-11 5407 207906 213313 Uterine/Uterovaginal prolapse 5 618.2 1.0138 genitourinary 3 128387424 A G rs2977562 EEFSEC 1.2e-11 10525 207563 218088 Polyp of female genital organs 3 622 1.0027 genitourinary 6 32333650 C T rs115378818 TSBP1 1.2e-11 500 393229 393729 Complication of colostomy or enterostomy 1 853 0.97444 injuries & poisonings 22 43928850 C T rs738408 PNPLA3 1.4e-11 836 377722 378558 Alcoholic liver damage 6 317.11 1.0 mental disorders 6 32112414 G C rs1269852 TNXB 1.4e-11 409 399660 400069 Lupus (localized and systemic) 2 695.4 1.0 dermatologic 9 22124505 A T rs1333047 AL359922.1 1.5e-11 3923 398704 402627 Peripheral vascular disease 3 443 1.0082 circulatory system 19 45686588 G A rs571017190 SNRPD2 1.6e-11 127 405102 405229 Muscular dystrophies 13 359.1 1.0848 neurological 6 32658698 G A rs9273368 HLA-DQB1 1.6e-11 467 395834 396301 Nephrotic syndrome without mention of glomerulonephritis 3 580.2 0.97444 genitourinary 7 19013110 G A rs57301765 TWIST1 1.7e-11 1185 397137 398322 Occlusion and stenosis of precerebral arteries 2 433.1 1.0 circulatory system 6 484453 C G rs116446171 EXOC2 1.8e-11 302 406469 406771 Disorders of protein plasma/amino-acid transport and metabolism 2 270 1.0313 endocrine/metabolic 8 123707678 T C rs2163535 ANXA13 2.4e-11 1763 403147 404910 Otitis media 3 381.1 1.0082 sense organs 6 32614835 G A rs3104414 HLA-DQA1 2.4e-11 2589 388553 391142 Chronic sinusitis 1 475 1.0054 respiratory 5 128014857 C T rs3749748 SLC12A2 2.4e-11 7213 395974 403187 Superficial cellulitis and abscess 4 681 1.011 dermatologic 6 32619017 T G rs9271365 HLA-DQA1 3e-11 275 401601 401876 Chronic hepatitis 3 070.4 1.0375 infectious diseases 11 30204981 G A rs11031006 FSHB 3e-11 16312 189127 205439 Disorders of menstruation and other abnormal bleeding from female genital tract 5 626 1.0224 genitourinary 15 78606661 C A rs56077333 CHRNA3 3.5e-11 2713 373883 376596 Obstructive chronic bronchitis 5 496.21 1.0054 respiratory 6 32619224 C T rs557048 HLA-DQA1 4.3e-11 135 395834 395969 Non-proliferative glomerulonephritis 2 580.12 1.0704 genitourinary 19 50861367 A G rs2735839 KLK2 5.1e-11 6374 400623 406997 Other abnormal blood chemistry 5 790.6 1.0082 symptoms 18 48922435 T C rs6507874 SMAD7 6e-11 5581 391484 397065 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum 2 159 1.011 neoplasms X 152689198 T A rs1439754558 MAGEA3 6.5e-11 138 406706 406844 Deficiency of humoral immunity 1 279.11 1.0669 endocrine/metabolic 6 127147129 A C rs7741021 RSPO3 6.6e-11 7052 386069 393121 Fracture of lower limb 2 800 1.0082 injuries & poisonings 5 36748379 C T rs186225833 SLC1A3 8.7e-11 119 363984 364103 Antisocial/borderline personality disorder 6 301.2 1.0635 mental disorders 4 110742777 C T rs78073007 PITX2 9.1e-11 8792 397138 405930 Cerebrovascular disease 3 433 1.011 circulatory system 3 75593873 G C rs1181027112 FRG2C 1e-10 1447 192419 193866 Benign neoplasm of ovary 8 220 1.0082 neoplasms 14 104205300 G A rs561848621 KIF26A 1.1e-10 523 405449 405972 Cancer of brain 7 191.11 0.97444 neoplasms 1 99584229 C A rs7543130 PALMD 1.1e-10 2629 404392 407021 Cardiac congenital anomalies 4 747.1 1.0027 congenital anomalies 20 35437976 G A rs143384 GDF5 1.2e-10 38496 364275 402771 Other arthropathies 11 716 1.108 musculoskeletal 7 121326736 A G rs3779381 WNT16 1.4e-10 6438 399565 406003 Osteoporosis 6 743.1 1.0224 musculoskeletal 14 104205300 G A rs561848621 KIF26A 1.6e-10 564 405450 406014 Cancer of brain and nervous system 6 191.1 0.97444 neoplasms 9 97784318 C T rs925489 FOXE1 1.6e-10 345 405668 406013 Thyroid cancer 1 193 1.0166 neoplasms 1 152313385 G A rs61816761 FLG 1.7e-10 2094 403085 405179 Atopic/contact dermatitis due to other or unspecified 3 939 1.0138 dermatologic 7 94636106 G A rs1009841083 SGCE 1.8e-10 470 389744 390214 Nontoxic uninodular goiter 5 241.1 0.97444 endocrine/metabolic 17 68677585 T TC rs3214623 FAM20A 1.8e-10 309 403146 403455 Otosclerosis 5 383 1.0313 sense organs 6 484453 C G rs116446171 EXOC2 1.9e-10 69 406469 406538 Macroglobulinemia 4 270.35 1.0254 endocrine/metabolic 10 133497600 A G rs574198244 SCART1 2e-10 910 169004 169914 Chronic prostatitis 4 601.12 1.0 genitourinary 8 123701385 G A rs13281855 ANXA13 2.1e-10 2150 403146 405296 Otitis media and Eustachian tube disorders 2 381 1.0082 sense organs 15 78606661 C A rs56077333 CHRNA3 2.1e-10 2954 373884 376838 Chronic bronchitis 6 496.2 1.0054 respiratory 9 31833003 A G rs10970547 ACO1 2.2e-10 113 406469 406582 Amyloidosis 1 270.33 1.0669 endocrine/metabolic 21 44740671 T C rs9983601 UBE2G2 2.2e-10 508 405774 406282 Otitis externa 1 380.1 0.97444 sense organs 22 43872362 G A rs896450253 PNPLA5 2.2e-10 269 406511 406780 Injury to other and unspecified nerves 4 957 1.0437 injuries & poisonings 7 64999274 C T rs1301038438 ERV3-1,ZNF117 2.3e-10 116 395834 395950 Abnormal results of function study of kidney 4 589 1.0635 genitourinary 8 127412547 A G rs7014346 POU5F1B 2.4e-10 3108 380932 384040 Colon cancer 2 153.2 1.0 neoplasms 7 85419190 T C rs13241159 SEMA3D 2.4e-10 353 400628 400981 Diseases of nail, NOS 1 703 1.0138 dermatologic 6 32343682 G A rs3132954 TSBP1 2.5e-10 3045 397602 400647 Inflammation of the eye 1 371 1.0 sense organs 6 160576086 A T rs74617384 LPA 2.7e-10 1378 398706 400084 Atherosclerosis 3 440 1.0 circulatory system 12 114228780 G A rs10774741 TBX5 2.8e-10 5900 210670 216570 stress incontinence, female 6 624.9 1.0166 genitourinary 8 62722254 A C rs536423929 NKAIN3 2.9e-10 302 169005 169307 Other inflammatory disorders of male genital organs 5 601.8 1.0313 genitourinary 11 87496262 G T rs190334528 TMEM135 3.1e-10 171 405081 405252 Disorders of phosphorus metabolism 2 275.53 1.0669 endocrine/metabolic 5 1356569 C T rs37004 CLPTM1L 3.1e-10 1341 169003 170344 Other disorders of prostate 5 602 1.0054 genitourinary 10 62492218 C T rs10822013 AC024598.1 3.2e-10 2483 213274 215757 Benign mammary dysplasias 3 610 1.0054 genitourinary 20 35437976 G A rs143384 GDF5 3.2e-10 36864 364275 401139 Arthropathy NOS 7 716.9 1.104 musculoskeletal 4 102276925 A G rs13135092 SLC39A8 3.4e-10 9628 377190 386818 Enthesopathy 1 726.1 1.0195 musculoskeletal 9 22124478 A G rs10757278 AL359922.1 3.5e-10 804 398706 399510 Atherosclerosis of the extremities 3 440.2 0.97444 circulatory system 3 177962442 AT A rs758115504 KCNMB2 3.6e-10 438 393432 393870 Generalized convulsive epilepsy 6 345.11 1.0 neurological 10 5899329 G A rs588742 FBH1 3.6e-10 256 398277 398533 Primary biliary cirrhosis 4 571.6 1.0406 digestive 2 37711101 G A rs753149879 CDC42EP3 3.6e-10 773 389622 390395 Obstruction of bile duct 9 575.2 0.97444 digestive 7 65314119 C G rs776676136 ZNF92 3.8e-10 196 400868 401064 Symptoms involving cardiovascular system 11 429.3 1.0635 circulatory system 6 10855360 G T rs9379839 AL024498.2 3.9e-10 780 403661 404441 Hyperparathyroidism 3 252.1 0.97444 endocrine/metabolic 6 32618459 C A rs11751024 HLA-DQA1 4.2e-10 1001 401602 402603 Viral warts & HPV 3 078 1.0 infectious diseases 14 104205300 G A rs561848621 KIF26A 4.2e-10 688 405450 406138 Manlignant and unknown neoplasms of brain and nervous system 5 191 0.97444 neoplasms 4 78806123 A T rs951059894 BMP2K 4.2e-10 490 406709 407199 Certain early complications of trauma or procedure 2 958 0.97444 injuries & poisonings 2 114999394 G A rs1053816295 DPP10 4.3e-10 1367 399528 400895 Disorders of vitreous body 12 379.2 1.0082 sense organs 21 34931505 A T rs1009711858 RUNX1 4.4e-10 95 405668 405763 Cancer of other endocrine glands 2 194 1.0534 neoplasms 6 168192144 C A rs779524792 FRMD1 4.5e-10 961 388553 389514 Chronic pharyngitis and nasopharyngitis 1 472 1.0 respiratory 6 32684419 T C rs9275152 HLA-DQB1 4.6e-10 348 387083 387431 Polyneuropathy in diabetes 2 250.6 1.0166 endocrine/metabolic X 152689198 T A rs1439754558 MAGEA3 4.6e-10 209 406706 406915 Immunity deficiency 1 279.1 1.0567 endocrine/metabolic 8 50313715 T C rs777283483 SNTG1 4.7e-10 280 403146 403426 Otorrhea 5 381.9 1.0375 sense organs 20 51475057 G A rs12480481 NFATC2 5e-10 878 392386 393264 Facial nerve disorders [CN7] 2 352.2 0.97444 neurological 6 32659207 A C rs4713573 HLA-DQB1 5.2e-10 2351 397601 399952 Inflammation of eyelids 3 371.3 1.0082 sense organs 5 160246270 T A rs770999474 CCNJL 5.2e-10 377 401102 401479 Peripheral or central vertigo 2 386.2 1.0082 sense organs 11 3442631 A G rs562153547 ZNF195 5.3e-10 521 400869 401390 Abnormal function study of cardiovascular system 2 429.2 0.97444 circulatory system 15 78540007 T C rs56117933 PSMA4 5.6e-10 2823 404343 407166 Cancer within the respiratory system 4 165 1.0 neoplasms 9 114939215 G A rs570345512 TNFSF8 5.6e-10 140 363984 364124 Obsessive-compulsive disorders 5 300.3 1.0635 mental disorders 6 32669238 C T rs1694133 HLA-DQB1 5.7e-10 2717 167467 170184 Redundant prepuce and phimosis/BXO 5 604.1 1.0 genitourinary 1 22141722 C T rs3820282 WNT4 6.5e-10 7429 207911 215340 Prolapse of vaginal walls 5 618.1 1.0138 genitourinary 1 99573963 G C rs1890753 PALMD 6.7e-10 2803 404392 407195 Cardiac and circulatory congenital anomalies 3 747 1.0 congenital anomalies 10 22253661 C T rs145146098 EBLN1 6.8e-10 1968 393013 394981 Bladder neck obstruction 2 596.1 1.011 genitourinary 2 43859452 G A rs4507142 ABCG8 7e-10 1992 404504 406496 Acute pancreatitis 1 577.1 1.0082 digestive 18 74845628 ATAAC A rs141452400 ZNF407 7.4e-10 1646 405229 406875 Other nonmalignant breast conditions 9 613 1.0082 genitourinary 20 51475057 G A rs12480481 NFATC2 7.5e-10 1370 392386 393756 Disorders of other cranial nerves 4 352 1.0082 neurological 6 32658661 A T rs9273367 HLA-DQB1 7.6e-10 7326 388398 395724 Iron deficiency anemias, unspecified or not due to blood loss 2 280.1 1.0138 hematopoietic 9 109060035 TAGTATA T rs1489195519 TMEM245 7.7e-10 699 396050 396749 Primary angle-closure glaucoma 4 365.2 0.97444 sense organs 21 36446573 A G rs2776288 CLDN14 7.8e-10 2401 399289 401690 Calculus of ureter 6 594.3 1.0054 genitourinary 6 32226853 G C rs3096690 NOTCH4 7.9e-10 57 400949 401006 Dermatitis herpetiformis 1 695.21 1.0027 dermatologic 15 78690879 TA T CHRNB4 8.2e-10 1890 398706 400596 Other aneurysm 2 442 1.0054 circulatory system 10 71658959 C T rs1027562123 CDH23 8.4e-10 113 398275 398388 Cirrhosis of liver without mention of alcohol 4 571.51 1.0635 digestive 9 125685192 T G rs1435729694 MAPKAP1 8.4e-10 1268 212249 213517 Placenta previa and abruptio placenta 4 635.3 1.0 pregnancy complications 12 88453224 A G rs7486184 KITLG 8.5e-10 286 180550 180836 Malignant neoplasm of testis 8 187.2 1.0224 neoplasms 6 49599506 A T rs866384639 RHAG 8.5e-10 4233 397133 401366 Occlusion of cerebral arteries 4 433.2 1.0054 circulatory system 16 85733885 G C rs380869 C16orf74 8.5e-10 96 398276 398372 Liver replaced by transplant 2 573.2 1.0567 digestive 2 113224233 A G rs6755639 PAX8 8.5e-10 2152 167471 169623 Other disorders of testis 3 603 1.0 genitourinary 1 169549811 C T rs6025 F5 8.9e-10 6228 400974 407202 Pain in limb 7 773 1.0138 symptoms 8 10938583 G T rs6984496 XKR6 9e-10 12369 378887 391256 Osteoarthrosis NOS 6 740.9 1.0375 musculoskeletal 12 88453224 A G rs7486184 KITLG 9.3e-10 448 180550 180998 Cancer of other male genital organs 1 187 0.97444 neoplasms 7 27671131 G A rs1248198441 HIBADH 9.7e-10 531 212191 212722 Umbilical cord complications during labor and delivery 3 663 1.0027 pregnancy complications 3 130948346 GT G rs374510888 ATP2C1 9.9e-10 170 396051 396221 Chorioretinal inflammations, scars, and other disorders of choroid 1 363 1.0635 sense organs 7 159103609 C T rs569395164 VIPR2 1e-09 190 400600 400790 Mild cognitive impairment 2 292.2 1.0567 mental disorders 2 227479954 A G rs888069617 AGFG1 1.1e-09 246 395834 396080 Nephritis and nephropathy without mention of glomerulonephritis 2 580.3 1.0437 genitourinary 18 55207524 T A rs1157500900 TCF4 1.2e-09 70 180551 180621 Malignant neoplasm of unspecified male genital organ 2 187.1 1.0313 neoplasms 8 25884287 G A rs73677235 EBF2 1.2e-09 259 403660 403919 Pituitary hypofunction 2 253.2 1.0437 endocrine/metabolic 2 66061260 A G rs560307191 MEIS1 1.2e-09 2183 379217 381400 Tachycardia NOS 2 427.7 1.0082 circulatory system 6 31720440 A G rs805294 LY6G6C,MPIG6B 1.2e-09 775 400950 401725 Prurigo and Lichen 2 695.7 0.97444 dermatologic 6 40727769 G A rs9367074 LRFN2 1.2e-09 41128 366074 407202 Abdominal pain 6 785 1.0567 symptoms 3 49509380 T G rs991361486 DAG1 1.2e-09 200 406578 406778 Toxic effect of (non-ethyl) alcohol and petroleum and other solvents 4 981 1.0601 injuries & poisonings 1 22308244 C T rs943706723 ZBTB40 1.3e-09 74 406123 406197 Acute (transverse) myelitis 2 323.2 1.0283 neurological 5 122727043 T C rs571798378 SNX2 1.3e-09 214 167468 167682 Male infertility and abnormal spermatozoa 7 609 1.0437 genitourinary X 86113292 TTTTA T DACH2 1.4e-09 330 406759 407089 Cancer of connective tissue 1 170.2 1.0224 neoplasms 7 125141336 T C rs574668338 POT1 1.4e-09 1057 363983 365040 Bipolar 3 296.1 1.0 mental disorders 5 1336063 A T rs457130 CLPTM1L 1.4e-09 9826 393016 402842 Other disorders of bladder 3 596 1.0166 genitourinary 9 20003454 G A rs538504761 SLC24A2 1.4e-09 1316 210932 212248 Cervicitis and endocervicitis 1 614.51 1.0 genitourinary 10 130109162 A C rs750361462 C10orf143 1.5e-09 84 401593 401677 Hypertrophy of salivary gland 5 527.1 1.0437 digestive 12 53920926 T A rs1016754907 HOXC13 1.5e-09 341 367706 368047 Gastroesophageal laceration-hemorrhage syndrome 1 530.7 1.0195 digestive 2 227479954 A G rs888069617 AGFG1 1.5e-09 252 395835 396087 Nephritis and nephropathy with pathological lesion 3 580.32 1.0437 genitourinary 6 96039244 C T rs1265969595 FUT9 1.5e-09 1328 378354 379682 Pyelonephritis 7 590 1.0082 genitourinary 4 65510796 C T rs11937800 EPHA5 1.5e-09 272 398899 399171 Open wound or laceration of eye or eyelid 2 870.1 1.0437 injuries & poisonings 12 31150342 T C rs770800394 DDX11 1.6e-09 190 391483 391673 Malignant neoplasm of small intestine, including duodenum 1 159.2 1.0635 neoplasms 1 165774286 A G rs2790049 TMCO1 1.6e-09 1035 396050 397085 Open-angle glaucoma 5 365.1 1.0 sense organs 5 74556252 A G rs185319737 ENC1 1.6e-09 1336 403885 405221 Pericarditis 2 420.2 1.0027 circulatory system 13 18751580 C T rs1238805155 TUBA3C 1.6e-09 1144 398704 399848 Raynaud's syndrome 3 443.1 1.0 circulatory system 1 219573884 TG T rs34791232 ZC3H11B 1.6e-09 3435 360061 363496 Ventral hernia 2 550.5 1.0054 digestive X 152689198 T A rs1439754558 MAGEA3 1.7e-09 249 406707 406956 Disorders involving the immune mechanism 2 279 1.0469 endocrine/metabolic 1 12248268 T G rs879702143 VPS13D 1.7e-09 1593 404469 406062 Abnormality of gait 5 350.2 1.011 neurological 22 43928850 C T rs738408 PNPLA3 1.7e-09 527 398276 398803 Portal hypertension 2 571.81 0.97444 digestive 21 38245059 G A rs759497710 KCNJ15 1.7e-09 73 400949 401022 Pemphigus and pemphigoid 10 695.22 1.0313 dermatologic 7 90827289 C A rs756720072 CDK14 1.7e-09 308 400950 401258 Rosacea 1 695.3 1.0313 dermatologic 5 64338451 G A rs181160440 RNF180 1.7e-09 352 377181 377533 Rupture of tendon, nontraumatic 1 727.6 1.0166 musculoskeletal 3 25435451 C A rs539335060 RARB 1.8e-09 157 405742 405899 Late effects of musculoskeletal and connective tissue injuries 2 905 1.0704 injuries & poisonings 6 32618459 C A rs11751024 HLA-DQA1 1.9e-09 360 403661 404021 Glucocorticoid deficiency 4 255.21 1.0166 endocrine/metabolic 18 69578522 C T rs79571725 DOK6 2e-09 589 401601 402190 Viral hepatitis 3 070 0.97444 infectious diseases 12 78852224 T A rs572224019 SYT1 2e-09 307 403146 403453 Otalgia 1 382 1.0224 sense organs 21 16775774 C T rs763004385 CXADR 2e-09 53 396443 396496 Hereditary disturbances in tooth structure 2 520.1 0.97444 digestive 2 238899039 G A rs961975567 TWIST2 2e-09 2263 212190 214453 Fetal distress and abnormal forces of labor 7 661 1.0 pregnancy complications 11 120063854 G A rs4936507 TRIM29 2.1e-09 55 398252 398307 Intestinal infection due to protozoa 4 008.7 1.0 infectious diseases 8 103201697 GA G rs1346500054 BAALC 2.1e-09 95 403660 403755 Acromegaly and gigantism 3 253.11 1.0534 endocrine/metabolic 2 199245017 T C rs260767 SATB2 2.2e-09 2164 380934 383098 Malignant neoplasm of rectum, rectosigmoid junction, and anus 6 153.3 1.0054 neoplasms 7 9910387 T A rs778274895 NDUFA4 2.2e-09 144 403025 403169 Malignant neoplasm of other urinary organs 7 189.4 1.0635 neoplasms 15 26458172 G A rs374459291 GABRB3 2.2e-09 180 403659 403839 Adrenal hyperfunction 2 255.1 1.0704 endocrine/metabolic 2 35287707 G A rs531236924 CRIM1 2.2e-09 552 397602 398154 Infection of the eye 3 369 0.97444 sense organs 1 234974469 G A rs553753391 TOMM20 2.2e-09 2865 210805 213670 Noninflammatory disorders of cervix 2 619.3 1.0 genitourinary 16 88306633 G A rs150212536 ZNF469 2.2e-09 53 400950 401003 Seborrheic dermatitis 9 690.1 0.97444 dermatologic 19 42047762 G A rs773985749 GRIK5 2.4e-09 5488 401714 407202 Symptoms concerning nutrition, metabolism, and development 5 1002 1.011 injuries & poisonings 4 163849421 T C rs371451295 MARCHF1 2.4e-09 361 405772 406133 Impacted cerumen 3 380.4 1.0138 sense organs 12 77867450 C T rs3934145 NAV3 2.4e-09 34214 367712 401926 Diseases of esophagus 8 530 1.0848 digestive 8 13155183 C G rs60739531 DLC1 2.5e-09 2230 404342 406572 Cancer of bronchus; lung 3 165.1 1.0054 neoplasms 6 52741666 T A rs892879632 GSTA2 2.5e-09 861 399653 400514 Other diseases of blood and blood-forming organs 3 289 0.97444 hematopoietic 6 152232879 C G rs71575922 SYNE1 2.5e-09 4036 210927 214963 Endometriosis 6 615 1.0054 genitourinary 2 229083969 G A rs568118401 PID1 2.6e-09 86 404523 404609 Hemorrhagic disorder due to intrinsic circulating anticoagulants 1 286.5 1.0469 hematopoietic 1 55282668 C T rs772772933 USP24 2.7e-09 105 400662 400767 Nonrheumatic tricuspid valve disorders 2 395.3 1.0635 circulatory system 13 96512882 TTTG T rs926287723 HS6ST3 2.7e-09 2471 379217 381688 Cardiac pacemaker/device in situ 5 426.9 1.0054 circulatory system 11 128076814 G T rs1252384564 ETS1 2.7e-09 2370 403746 406116 Sciatica 1 764 1.0027 symptoms 8 17439656 A G rs928638497 MTMR7 2.8e-09 1814 399782 401596 Hyposmolality and/or hyponatremia 3 276.12 1.0082 endocrine/metabolic 4 87304444 C G rs565615993 HSD17B13 2.8e-09 4224 400664 404888 Heart valve disorders 4 395 1.0082 circulatory system 11 46496726 C T rs976341753 AMBRA1 2.8e-09 134 403885 404019 Hypertrophic obstructive cardiomyopathy 5 425.11 1.0704 circulatory system 11 20603360 G T rs181821254 SLC6A5 2.8e-09 658 406516 407174 Symptoms of the muscles 3 772 0.97444 symptoms 13 69195573 C A rs1371045755 KLHL1 2.9e-09 8895 398249 407144 Intestinal infection 5 008 1.011 infectious diseases 9 22052735 T C rs6475604 AL359922.1 2.9e-09 1029 396050 397079 Primary open angle glaucoma 5 365.11 0.97444 sense organs 18 49421999 G A rs972812660 DYM 2.9e-09 8759 210807 219566 Noninflammatory female genital disorders 5 619 1.0082 genitourinary 18 53227723 A G rs62100775 DCC 3e-09 12456 363980 376436 Mood disorders 2 296 1.0313 mental disorders 9 22123767 A C rs10738610 AL359922.1 3e-09 930 398704 399634 Abdominal aortic aneurysm 4 442.11 0.97444 circulatory system 8 80393921 G C rs368925034 ZBTB10 3e-09 267 333379 333646 Impaction of intestine 2 560.2 1.0406 digestive 4 110780642 G T rs1906615 PITX2 3.1e-09 5627 400865 406492 Congestive heart failure; nonhypertensive 7 428 1.011 circulatory system 6 32469562 C T rs374532386 HLA-DRA 3.1e-09 822 398703 399525 Polyarteritis nodosa and allied conditions 4 446 0.97444 circulatory system 6 160135153 A G rs3798170 SLC22A1 3.1e-09 1324 398706 400030 Other disorders of arteries and arterioles 2 447 1.0054 circulatory system 5 94668877 A G rs189918011 SLF1 3.1e-09 28643 376439 405082 Gastritis and duodenitis 6 535 1.0601 digestive 9 28047049 T C rs182158531 LINGO2 3.1e-09 1363 189127 190490 Infertility, female 5 626.8 1.0 genitourinary 12 47896172 G A rs1006800498 VDR 3.1e-09 102 402139 402241 Acquired acanthosis nigricans 5 701.6 1.0567 dermatologic 22 29452646 A G rs1390021212 RFPL1 3.1e-09 89 406579 406668 Toxic effect of other substances, chiefly nonmedicinal as to source 1 989 1.0437 injuries & poisonings 13 32380424 G A rs7328654 BRCA2 3.2e-09 634 405058 405692 Cancer of larynx, pharynx, nasal cavities 1 149 0.97444 neoplasms 4 45216706 A T rs758442071 GNPDA2 3.2e-09 623 367909 368532 Varicose veins of lower extremity, symptomtic 3 454.11 0.97444 circulatory system 8 3587014 G A rs1047346135 CSMD1 3.2e-09 4411 390235 394646 Other and unspecified disc disorder 3 722.9 1.0138 musculoskeletal 19 28148570 C T rs766270363 UQCRFS1 3.3e-09 205 391483 391688 Malignant neoplasm of gallbladder and extrahepatic bile ducts 4 159.3 1.0601 neoplasms 20 53367788 G C rs143059624 TSHZ2 3.3e-09 176 405449 405625 Cancer of eye 1 190 1.0635 neoplasms 20 19496121 G A rs6046142 SLC24A3 3.3e-09 1816 399532 401348 Aphakia and other disorders of lens 2 379.3 1.0054 sense organs 5 153865540 T A rs17115315 GRIA1 3.3e-09 113 398705 398818 Atherosclerosis of renal artery 1 440.1 1.0635 circulatory system 9 71683857 C T rs572163979 CEMIP2 3.3e-09 31930 367712 399642 Esophagitis, GERD and related diseases 8 530.1 1.0811 digestive 4 59759290 C G rs1006285030 ADGRL3 3.3e-09 1684 333380 335064 Flatulence 1 561.2 1.011 digestive 3 64267784 C T rs1482178536 PRICKLE2 3.3e-09 61 210936 210997 Acute inflammatory pelvic disease 3 614.31 1.0224 genitourinary 3 143612030 A G rs746981761 SLC9A9 3.3e-09 1268 207570 208838 Hypertrophy of female genital organs 2 623 1.0 genitourinary 1 1020947 C T rs111893801 AGRN 3.3e-09 3910 403292 407202 Fever of unknown origin 1 783 1.0 symptoms 3 77153500 C T rs765716642 ROBO2 3.4e-09 2723 398253 400976 Bacterial enteritis 2 008.5 1.0027 infectious diseases 9 133045928 T C rs78749627 GTF3C5 3.4e-09 2962 403918 406880 Visual disturbances 2 368 1.0 sense organs 5 95322638 C T rs186982985 MCTP1 3.4e-09 3320 210804 214124 Disorders of uterus, NEC 7 619.2 1.0 genitourinary 22 36219778 G A rs998596512 APOL2 3.4e-09 693 405003 405696 Congenital anomalies of genital organs 1 751.1 0.97444 congenital anomalies 6 32618459 C A rs11751024 HLA-DQA1 3.5e-09 361 403661 404022 Adrenal hypofunction 4 255.2 1.0166 endocrine/metabolic 15 64893312 T C rs1014469087 AC069368.1 3.5e-09 98 404523 404621 Von willebrand's disease 12 286.11 1.0534 hematopoietic 12 55721801 C T rs3138142 AC009779.3,RDH5 3.6e-09 1249 404788 406037 Myopia 1 367.1 1.0027 sense organs 7 114383427 T C rs10244257 FOXP2 3.6e-09 763 401102 401865 Labyrinthitis 1 386.3 0.97444 sense organs 8 19643487 A C rs778922534 CSGALNACT1 3.6e-09 4464 400864 405328 Heart failure NOS 5 428.2 1.0082 circulatory system 5 153600072 G A rs762748914 GRIA1 3.6e-09 2226 217862 220088 Other complications of pregnancy NEC 1 646 1.0054 pregnancy complications 12 124715039 G A rs556343815 SCARB1 3.6e-09 65 364268 364333 Arthropathy associated with neurological disorders 4 713.5 0.97444 musculoskeletal 17 15665434 G A rs375636583 TRIM16 3.6e-09 402 390235 390637 Disorders of sacrum 1 724.1 1.0 musculoskeletal 4 153154008 G A rs1325202108 AC013477.1,TRIM2 3.6e-09 7349 377186 384535 Other disorders of synovium, tendon, and bursa 2 727 1.0054 musculoskeletal 7 101845078 CTCTT C rs1322024871 CUX1 3.7e-09 16197 391005 407202 Other ill-defined and unknown causes of morbidity and mortality 11 1019 1.0669 injuries & poisonings 20 3164545 C G rs144338308 LZTS3 3.7e-09 451 388396 388847 Iron deficiency anemia secondary to blood loss (chronic) 2 280.2 1.0 hematopoietic 13 107212788 G A rs774984826 FAM155A 3.7e-09 443 406124 406567 Meningitis 4 320 1.0 neurological 16 65729479 A G rs1124435 CDH11 3.7e-09 1493 393431 394924 Hemiplegia 1 342 1.0082 neurological 4 688308 C T rs563136561 SLC49A3 3.7e-09 286 398706 398992 Atherosclerosis of aorta 4 440.9 1.0344 circulatory system 11 72706258 T C rs978523236 ARAP1 3.7e-09 54 398705 398759 Arterial dissection 2 442.4 0.97444 circulatory system 21 16037518 G A rs867996973 USP25 3.8e-09 346 406856 407202 Benign neoplasm of respiratory and intrathoracic organs 2 212 1.0195 neoplasms 6 85973695 C T rs576997067 SYNCRIP 3.8e-09 2599 399656 402255 Lymphadenitis 2 289.4 1.0 hematopoietic 15 39329851 A G rs1033568904 THBS1 3.8e-09 642 405771 406413 Disorders of external ear 5 380 0.97444 sense organs 8 25471649 G A rs537381280 CDCA2 3.8e-09 5783 386243 392026 Hypotension 3 458 1.0082 circulatory system 2 8058782 A G rs1347011624 ID2 3.8e-09 1814 386069 387883 Fracture of neck of femur 2 800.1 1.0138 injuries & poisonings 1 170753546 G T rs984651100 PRRX1 3.9e-09 187 403659 403846 Pituitary hyperfunction 5 253.1 1.0635 endocrine/metabolic 2 218101118 A T rs111483161 RUFY4 3.9e-09 172 403144 403316 Mastoiditis & related conditions 2 381.3 1.0669 sense organs 1 51430797 T A rs897673201 EPS15 3.9e-09 1333 395971 397304 Other local infections of skin and subcutaneous tissue 3 686 1.0027 dermatologic 9 113793880 G A rs192011904 ZNF618 4e-09 718 403881 404599 Endocarditis 2 420.3 0.97444 circulatory system 2 224907413 C T rs778419105 DOCK10 4e-09 386 398702 399088 Giant cell arteritis 3 446.5 1.0054 circulatory system 2 165108700 T C rs1335169423 SCN3A 4e-09 3455 398278 401733 Abnormal results of function study of liver 1 573.7 1.0054 digestive 1 31567441 AAAAC A rs550434026 TINAGL1 4e-09 584 404390 404974 Cardiac shunt/ heart septal defect 2 747.11 0.97444 congenital anomalies 6 31781365 G A rs915652 VARS1 4.1e-09 1112 389741 390853 Secondary hypothyroidism 1 244.1 0.97444 endocrine/metabolic 6 32229442 T G rs3132948 NOTCH4 4.1e-09 1883 373884 375767 Bronchiectasis 2 496.3 1.0054 respiratory 22 43928847 C G rs738409 PNPLA3 4.1e-09 974 398274 399248 Liver abscess and sequelae of chronic liver disease 1 571.8 1.0 digestive 18 53227723 A G rs62100775 DCC 4.2e-09 11816 363981 375797 Depression 1 296.2 1.0313 mental disorders 17 80648966 G A rs960265022 RPTOR 4.2e-09 359 405101 405460 Myopathy 1 359.2 1.0166 neurological 7 2222359 C T rs557374180 AC069288.1,MAD1L1 4.2e-09 399 399529 399928 Disorders of iris and ciliary body 3 379.5 1.0 sense organs 20 42491192 C A rs546310576 PTPRT 4.2e-09 183 189130 189313 Symptomatic menopause 1 627.2 1.0635 genitourinary 17 15665434 G A rs375636583 TRIM16 4.2e-09 405 390235 390640 Disorders of coccyx 1 724.2 1.0 musculoskeletal 12 42727294 T C rs776531807 PRICKLE1 4.2e-09 11651 395550 407201 Nausea and vomiting 5 789 1.0138 symptoms 1 50674037 G A rs532759932 FAF1 4.3e-09 2827 399780 402607 Hypovolemia 7 276.5 1.0 endocrine/metabolic 18 782681 T C rs763832807 YES1 4.3e-09 1809 393433 395242 Degenerative disease of the spinal cord 1 334 1.011 neurological 4 17956833 A T rs575714371 LCORL 4.3e-09 144 393432 393576 Nonspecific abnormal findings on radiological and other examination of skull and head 5 346.1 1.0669 neurological 2 112806053 G A rs1036451939 IL1A 4.3e-09 759 397603 398362 Disorders of conjunctiva 5 372 0.97444 sense organs 8 12022390 C T rs1005915620 DEFB134 4.3e-09 1553 393243 394796 Hallux rigidus 2 735.23 1.011 musculoskeletal 2 124112678 T C rs780267274 CNTNAP5 4.3e-09 4265 401889 406154 Superficial injury without mention of infection 2 915 1.011 injuries & poisonings 1 198603277 CA C rs145405017 PTPRC 4.3e-09 225 403085 403310 Adverse reaction to serum or vaccine 3 941 1.0534 injuries & poisonings X 48775200 T C rs190666180 GLOD5 4.4e-09 507 395583 396090 Pulmonary congestion and hypostasis 3 503 0.97444 respiratory 17 50035589 A T rs138347258 ITGA3 4.5e-09 214 399529 399743 Nystagmus and other irregular eye movements 2 378.2 1.0567 sense organs 11 96694103 A G rs7936111 JRKL 4.5e-09 449 402828 403277 Conductive hearing loss 3 389.2 1.0 sense organs 6 85409605 C T rs770497879 NT5E 4.5e-09 559 396444 397003 Chronic periodontitis 1 523.32 0.97444 digestive 8 14063851 G C rs1180032350 SGCZ 4.5e-09 927 396443 397370 Diseases of the jaws 2 526 0.97444 digestive 5 54825369 T C rs905239982 ESM1 4.5e-09 113 363561 363674 Sacroiliitis NEC 3 715.1 1.0601 musculoskeletal 5 62988676 C T rs187728802 IPO11 4.6e-09 966 201517 202483 Malignant neoplasm of ovary and other uterine adnexa 2 184.1 0.97444 neoplasms 1 1010036 C T rs550257025 ISG15 4.6e-09 67 405449 405516 Benign neoplasm of eye, uveal 2 224.1 1.0138 neoplasms 2 25273293 G A rs778305602 DNMT3A 4.6e-09 62 401593 401655 Disturbance of salivary secretion 2 527.7 0.97444 digestive 9 2734047 A G rs111780155 PUM3 4.7e-09 63 167468 167531 Infertility, male 4 609.1 1.0138 genitourinary 1 198060620 T A rs12411267 NEK7 4.8e-09 578 406624 407202 Burns 1 1000 0.97444 injuries & poisonings 2 123014133 C G rs571714114 CNTNAP5 4.8e-09 264 405058 405322 Cancer of larynx 4 149.4 1.0375 neoplasms 2 132138690 A T rs911675592 ANKRD30BL 4.8e-09 466 363985 364451 Psychogenic and somatoform disorders 4 303 0.97444 mental disorders 11 114654050 G A rs557896803 NXPE2 4.8e-09 327 395583 395910 Other alveolar and parietoalveolar pneumonopathy 1 504 1.0224 respiratory 8 74306002 T G rs72663682 JPH1 4.9e-09 2105 403881 405986 Carditis 3 420 1.0082 circulatory system 5 34911809 G C rs1805328 RAD1 4.9e-09 893 398276 399169 Jaundice (not of newborn) 3 573.5 0.97444 digestive 18 69871923 G C rs945580986 CD226 5e-09 235 386239 386474 Iatrogenic hypotension 3 458.2 1.0469 circulatory system 18 79402217 C T rs759975572 NFATC1 5e-09 7136 399771 406907 Peptic ulcer (excl. esophageal) 2 531 1.0138 digestive 1 53118293 G A rs181554786 SLC1A7 5.1e-09 200 387081 387281 Type 2 diabetes with renal manifestations 1 250.22 1.0224 endocrine/metabolic 18 29494933 A G rs753261278 CDH2 5.1e-09 9061 398129 407190 Other symptoms of respiratory system 3 512 1.0138 respiratory 14 71836075 A G rs192821680 SIPA1L1 5.1e-09 186 397535 397721 Hidradenitis 3 705.3 1.0567 dermatologic 9 18607230 T C rs1041403866 ADAMTSL1 5.2e-09 9195 398007 407202 Complications of surgical and medical procedures 1 1011 1.0054 injuries & poisonings 4 6152966 C T rs139798769 C4orf50,JAKMIP1 5.2e-09 317 369610 369927 Benign neoplasm of bone and articular cartilage 3 213 1.0254 neoplasms 11 134525957 A C rs1018074097 B3GAT1 5.2e-09 308 405668 405976 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) 3 227.3 1.0313 neoplasms 6 10855360 G T rs9379839 AL024498.2 5.2e-09 872 403661 404533 Disorders of parathyroid gland 4 252 0.97444 endocrine/metabolic 1 74006247 A G rs17094698 LRRIQ3 5.2e-09 3764 399654 403418 Diseases of white blood cells 1 288 1.0 hematopoietic 15 84394607 G A rs576901275 GOLGA6L4 5.2e-09 347 378889 379236 Osteoarthrosis, localized, secondary 1 740.12 1.0166 musculoskeletal 18 71757088 C T rs184828637 CBLN2 5.3e-09 161 395155 395316 Other nondiabetic retinopathy 1 362.3 1.0669 sense organs 3 19892554 G A rs78833176 EFHB 5.3e-09 310 389420 389730 Cyst of bone 3 733.2 1.0166 musculoskeletal 7 121326736 A G rs3779381 WNT16 5.3e-09 7609 399565 407174 Osteoporosis, osteopenia and pathological fracture 4 743 1.0195 musculoskeletal 4 89704960 G A rs356182 SNCA 5.4e-09 1127 393434 394561 Parkinson's disease 2 332 1.0 neurological 16 77018488 A G rs772232038 MON1B 5.4e-09 2668 404470 407138 Abnormal movement 1 350 1.0027 neurological 11 106384209 CT C rs1341717851 AASDHPPT 5.4e-09 303 397697 398000 Symptoms involving respiratory system and other chest symptoms 4 519.9 1.0283 respiratory X 27226163 C T rs1007481047 PPP4R3C 5.4e-09 175 405393 405568 Pallor and flushing 2 782.6 1.0669 symptoms 16 65476112 C T rs143697787 CDH11 5.5e-09 105 405057 405162 Cancer of major salivary glands 2 145.3 1.0635 neoplasms 6 123010398 A T rs188100688 CLVS2 5.5e-09 230 405784 406014 Other disorders of lipoid metabolism 4 277.5 1.0534 endocrine/metabolic 8 10134226 A G rs76675074 MSRA 5.6e-09 2073 405035 407108 Hemoptysis 2 516.1 1.011 respiratory 9 89890397 C T rs1446368447 GADD45G 5.6e-09 363 380139 380502 Hormones and synthetic substitutes causing adverse effects in therapeutic use 2 962.3 1.0138 injuries & poisonings 18 29729787 T C rs981014522 DSC3 5.7e-09 71 399653 399724 Eosinophilia 2 288.3 1.0195 hematopoietic 4 37662921 A G rs771882503 RELL1 5.8e-09 1432 368845 370277 Neoplasm of uncertain behavior 2 199 1.0082 neoplasms 3 197367402 G T rs886150991 DLG1 5.8e-09 968 399785 400753 Hyperpotassemia 2 276.13 0.97444 endocrine/metabolic 10 76976761 GC G rs1284857817 KCNMA1 5.8e-09 2885 401683 404568 Disturbance of skin sensation 5 687.4 1.0 dermatologic 16 64664845 A G rs974451002 CDH11 5.8e-09 7870 390237 398107 Spondylosis and allied disorders 1 721 1.0254 musculoskeletal 7 30236545 G A rs6462196 ZNRF2 5.9e-09 237 210673 210910 Dystrophy of female genital tract 11 624.1 1.0469 genitourinary 3 15363625 G A rs141557666 METTL6 5.9e-09 2876 210672 213548 Pain and other symptoms associated with female genital organs 1 625 1.0 genitourinary 2 134389842 T C rs759798467 MGAT5 5.9e-09 1238 393232 394470 Mechanical complication of unspecified genitourinary device, implant, and graft 3 857 1.0 injuries & poisonings 5 158367415 A AT rs199902576 EBF1 5.9e-09 422 406511 406933 Spinal cord injury without evidence of spinal bone injury 2 952 1.0 injuries & poisonings 9 15243052 A G rs966562031 TTC39B 6e-09 21690 368861 390551 Chemotherapy 4 197 1.0166 neoplasms 9 32396556 G A rs764706784 ACO1 6e-09 2233 393437 395670 Convulsions 2 345.3 1.0027 neurological 11 12209325 G T rs777604208 MICAL2 6e-09 10377 333382 343759 Constipation 1 563 1.0138 digestive 2 43859452 G A rs4507142 ABCG8 6e-09 2666 404505 407171 Diseases of pancreas 1 577 1.0 digestive 5 96436132 T C rs796370465 PCSK1 6.1e-09 138 389743 389881 Exophthalmos 5 242.3 1.0635 endocrine/metabolic 10 86890603 T A rs12259628 BMPR1A 6.1e-09 139 407041 407180 Intestinal disaccharidase deficiencies and disaccharide malabsorption 3 271.3 1.0635 endocrine/metabolic 8 29516563 C G rs746722557 DUSP4 6.1e-09 208 406643 406851 Spina bifida 2 752.11 1.0567 congenital anomalies 19 51578821 A G rs553434560 ZNF175 6.2e-09 1375 201516 202891 Cancer of other female genital organs 3 184 1.0027 neoplasms 13 105461343 G A rs566553219 DAOA 6.2e-09 435 406081 406516 Congenital osteodystrophies 3 756.5 1.0 congenital anomalies 1 147548532 A G rs587729398 BCL9 6.3e-09 267 393433 393700 Cerebral edema and compression of brain 1 348.2 1.0406 neurological 6 53138320 G A rs540949092 GCM1 6.3e-09 2353 396446 398799 Disturbances in tooth eruption 2 520.2 1.0027 digestive 6 119689463 T A rs567032411 MAN1A1 6.3e-09 228 397535 397763 Disorders of sweat glands 5 705 1.0469 dermatologic 7 147906426 C A rs1271667844 CNTNAP2 6.3e-09 2205 386070 388275 Fracture of ankle and foot 1 801 1.0054 injuries & poisonings 5 165626816 G A rs555789604 TENM2 6.3e-09 178 398898 399076 Open wound of foot except toe(s) alone 2 871.3 1.0669 injuries & poisonings 9 15844446 G A CCDC171 6.4e-09 563 367907 368470 Other venous embolism and thrombosis 2 452 0.97444 circulatory system 1 11580144 T G rs2817638 DISP3 6.4e-09 2667 396440 399107 Other diseases of the teeth and supporting structures 1 525 1.0 digestive 17 78260123 T C rs565197438 TMEM235 6.4e-09 1053 395835 396888 Glomerulonephritis 4 580.1 1.0 genitourinary 5 97646954 T C rs914830815 RIOK2 6.5e-09 117 379216 379333 Supraventricular premature beats 1 427.61 1.0635 circulatory system 22 37468443 G A rs560458799 MFNG 6.5e-09 1457 398705 400162 Aortic aneurysm 1 442.1 1.0054 circulatory system 3 138158613 C A rs149132966 DBR1 6.5e-09 1865 367707 369572 Stricture and stenosis of esophagus 4 530.3 1.011 digestive 14 46366961 C A rs777493158 RPL10L 6.6e-09 5955 401247 407202 Other tests 6 1010 1.0082 injuries & poisonings 6 5513562 G A rs778868783 FARS2 6.6e-09 275 399530 399805 Paralytic strabismus 6 378.5 1.0406 sense organs 9 128612194 A G rs757109566 SPTAN1 6.6e-09 137 400948 401085 Bullous dermatoses 9 695.2 1.0739 dermatologic 6 16415237 T C rs1020305899 ATXN1 6.6e-09 216 406232 406448 Other and unspecified congenital anomalies 1 759 1.0567 congenital anomalies 5 147428536 CA C rs142373641 DPYSL3 6.7e-09 1066 388395 389461 Megaloblastic anemia 4 281.1 1.0 hematopoietic 5 179463646 T C rs1251695125 RUFY1 6.7e-09 1829 397604 399433 Ptosis of eyelid 1 374.3 1.011 sense organs 4 43908027 GA G rs911299346 KCTD8 6.7e-09 332 377181 377513 Synoviopathy 4 726.2 1.0195 musculoskeletal 14 46907570 C A rs3007112 MDGA2 6.8e-09 1006 377182 378188 Rheumatism, unspecified and fibrositis 3 729.1 0.97444 musculoskeletal 2 201177085 T C rs557605380 CFLAR 6.8e-09 499 400909 401408 Articular cartilage disorder 1 742.8 0.97444 musculoskeletal 5 135834716 T G rs141243065 SLC25A48 6.8e-09 6092 380140 386232 Poisoning by analgesics, antipyretics, and antirheumatics 1 965 1.0138 injuries & poisonings 3 31867950 T C rs7642278 OSBPL10 6.8e-09 582 380138 380720 Adverse effects of sedatives or other central nervous system depressants and anesthetics 2 967 0.97444 injuries & poisonings 1 202170315 CAA C rs565355303 PTPN7 6.9e-09 259 402715 402974 Hodgkin's disease 5 201 1.0469 neoplasms 5 22848251 A T rs960237002 CDH12 6.9e-09 164 371432 371596 Mixed hyperlipidemia 3 272.13 1.0138 endocrine/metabolic 1 167598008 G A rs965316315 RCSD1 6.9e-09 606 403145 403751 Cholesteatoma 4 385.3 0.97444 sense organs 3 166200589 A C rs770426273 BCHE 6.9e-09 698 380137 380835 Adverse drug events and drug allergies 4 979 0.97444 injuries & poisonings 5 17032877 G A rs575291414 BASP1 7e-09 612 403916 404528 Subjective visual disturbances 1 368.9 0.97444 sense organs 7 3157926 T A rs6946551 CARD11 7e-09 1972 212250 214222 Hemorrhage during pregnancy; childbirth and postpartum 3 635 1.0 pregnancy complications X 71265904 C T rs1377161621 NONO 7.1e-09 455 402829 403284 Sensorineural hearing loss 9 389.1 1.0 sense organs 6 148544906 A C rs756832688 SASH1 7.1e-09 447 400269 400716 Primary pulmonary hypertension 3 415.21 1.0 circulatory system 13 42882590 C T rs989184907 EPSTI1 7.1e-09 143 395582 395725 Respiratory arrest 3 509.5 1.0567 respiratory 3 111055389 G C rs571263535 NECTIN3 7.1e-09 1772 396444 398216 Diseases of pulp and periapical tissues 3 522 1.0082 digestive 1 212270753 G A rs533211678 PPP2R5A 7.3e-09 1054 399781 400835 Acidosis 4 276.41 1.0 endocrine/metabolic 1 74006247 A G rs17094698 LRRIQ3 7.3e-09 3166 399653 402819 Decreased white blood cell count 4 288.1 1.0 hematopoietic 3 107763161 C T rs542833621 BBX 7.3e-09 73 396444 396517 Atrophy of edentulous alveolar ridge 14 525.2 1.0195 digestive 9 103767717 G A rs940622762 SMC2 7.3e-09 1931 399286 401217 Hydronephrosis 1 595 1.0138 genitourinary 1 74006247 A G rs17094698 LRRIQ3 7.4e-09 3174 399653 402827 Neutropenia 3 288.11 1.0 hematopoietic 1 224281109 G A rs201855587 NVL 7.4e-09 3717 399531 403248 Other disorders of eye 3 379 1.0054 sense organs 18 29494933 A G rs753261278 CDH2 7.4e-09 5847 398129 403976 Shortness of breath 2 512.7 1.011 respiratory 3 180431389 A G rs539324805 TTC14 7.5e-09 298 401594 401892 Glossitis 2 529.1 1.0313 digestive 4 173389281 T A rs778920963 SCRG1 7.7e-09 328 402714 403042 Myeloid leukemia, acute 3 204.21 1.0254 neoplasms 6 33080680 C G rs1126504 HLA-DPA1,HLA-DPB1 7.7e-09 188 398705 398893 Wegener's granulomatosis 5 446.4 1.0669 circulatory system 11 45008136 G A rs375033035 TP53I11 7.7e-09 1901 393243 395144 Other acquired musculoskeletal deformity 4 738 1.0138 musculoskeletal 11 46080698 T C rs1022781147 PHF21A 7.8e-09 1238 403884 405122 Primary/intrinsic cardiomyopathies 4 425.1 1.0 circulatory system 6 121282402 TACA T rs898928455 TBC1D32 7.8e-09 239 398705 398944 Arteritis NOS 2 446.9 1.0501 circulatory system 19 57507914 G A rs527241692 AC003005.1,ZNF773 7.8e-09 1142 380139 381281 Opiates and related narcotics causing adverse effects in therapeutic use 3 965.1 1.0 injuries & poisonings 4 102137353 G A rs117467740 BANK1 7.9e-09 291 406125 406416 Other CNS infection and poliomyelitis 3 324 1.0375 neurological 8 122885555 G T rs758961788 ZHX2 7.9e-09 1895 328789 330684 Hypertensive heart and/or renal disease 2 401.2 1.0138 circulatory system 11 100291923 C T rs1056302139 CNTN5 7.9e-09 70 212211 212281 Other high-risk pregnancy 1 638 1.0224 pregnancy complications 1 216019889 C T rs115907570 USH2A 7.9e-09 5750 401452 407202 Disorder of skin and subcutaneous tissue NOS 1 689 1.0027 dermatologic 16 88306633 G A rs150212536 ZNF469 7.9e-09 71 400950 401021 Erythematosquamous dermatosis 6 690 1.0224 dermatologic 1 64477865 A C rs531590357 CACHD1 7.9e-09 216 402139 402355 Keloid scar 2 701.4 1.0534 dermatologic 4 9002955 G T rs1246862233 HMX1 7.9e-09 110 400908 401018 Hemarthrosis 1 741.5 1.0635 musculoskeletal 1 99656436 A G rs532780200 PALMD 8e-09 239 399782 400021 Hyperosmolality and/or hypernatremia 2 276.11 1.0534 endocrine/metabolic 5 147428536 CA C rs142373641 DPYSL3 8e-09 1111 388395 389506 Other deficiency anemia 3 281 1.0 hematopoietic 10 132157200 GTTCTC G rs988167255 JAKMIP3 8e-09 103 388395 388498 Autoimmune hemolytic anemias 2 283.1 1.0635 hematopoietic 6 160654352 AC A rs71033586 LPA 8e-09 866 398706 399572 Stricture of artery 2 447.1 0.97444 circulatory system 17 74318321 G T rs1403902940 DNAI2 8e-09 112 406579 406691 Toxic effect of noxious substances eaten as food 2 988 1.0567 injuries & poisonings 4 152991612 G A rs192486023 FHDC1 8.1e-09 3919 393015 396934 Other disorders of urethra and urinary tract 3 597 1.0082 genitourinary 14 66811710 T A rs965978742 GPHN 8.1e-09 222 186044 186266 Congenital anomalies of male genital organs 1 751.12 1.0567 congenital anomalies 12 31975703 CTG C rs760226485 RESF1 8.2e-09 303 201515 201818 Cancer of other female genital organs (excluding uterus and ovary) 3 184.2 1.0313 neoplasms 5 123193290 C A rs897493343 PRDM6 8.2e-09 169 167468 167637 Abnormal spermatozoa 4 609.2 1.0635 genitourinary 4 116238178 C A rs556450329 MTRNR2L13 8.2e-09 101 377181 377282 Panniculitis 4 729.3 1.0601 musculoskeletal 2 27801032 C T rs1180082304 MRPL33,RBKS 8.3e-09 82 395155 395237 Hereditary retinal dystrophies 3 362.7 1.0344 sense organs X 86420958 AG A rs773753572 DACH2 8.3e-09 104 388553 388657 Chronic laryngitis 1 473.1 1.0567 respiratory 4 106282808 A G rs1348827864 TBCK 8.4e-09 166 392087 392253 Tuberculosis 2 010 1.0704 infectious diseases 1 35301865 A C rs777974864 ZMYM4 8.4e-09 193 403146 403339 Eustachian tube disorders 7 381.2 1.0601 sense organs 11 17341924 A C rs547440875 NUCB2 8.4e-09 167 404388 404555 Congenital anomalies of peripheral vascular system 1 747.2 1.0669 congenital anomalies 12 79819916 A G rs1218268285 PPP1R12A 8.5e-09 439 210672 211111 Atrophy of female genital tract 2 624.2 1.0 genitourinary 7 102963663 A T rs138864542 FBXL13 8.5e-09 1833 386070 387903 Fracture of foot 1 801.1 1.0082 injuries & poisonings 4 2692235 C T rs1018249687 FAM193A 8.6e-09 12085 392082 404167 Bacterial infection NOS 3 041 1.0138 infectious diseases 16 89986640 A C rs9939542 CENPBD1 8.6e-09 16407 368844 385251 Malignant neoplasm, other 4 195.1 1.0138 neoplasms 5 67991055 A G rs551551251 PIK3R1 8.7e-09 1248 218840 220088 Late pregnancy and failed induction 4 645 1.0 pregnancy complications 16 79238199 C G rs1327360994 WWOX 8.7e-09 466 389419 389885 Osteochondropathies 4 732 1.0 musculoskeletal 11 123484683 A G rs35923643 GRAMD1B 8.8e-09 505 402712 403217 Lymphoid leukemia, chronic 4 204.12 0.97444 neoplasms 15 29487571 C T rs188919699 FAM189A1 8.8e-09 2111 379217 381328 Atrioventricular [AV] block 2 426.2 1.0082 circulatory system 3 73037639 T G rs190923891 PPP4R2 8.8e-09 5901 396443 402344 Pneumococcal pneumonia 1 480.11 1.0082 respiratory 2 34354913 G C rs537325855 FAM98A 8.9e-09 1679 396444 398123 Gingival and periodontal diseases 2 523 1.0054 digestive 3 20638243 GT G rs200627131 SGO1 8.9e-09 464 333378 333842 Diarrhea 3 561.1 1.0 digestive 8 7045920 C G rs1464968260 DEFA5 9e-09 2079 404231 406310 Symptoms involving head and neck 1 293 1.011 mental disorders 12 20822033 G A rs988398475 SLCO1B3,SLCO1B3-SLCO1B7 9e-09 2445 388552 390997 Epistaxis or throat hemorrhage 2 477 1.0027 respiratory 1 95181580 A T rs12062231 TLCD4,TLCD4-RWDD3 9e-09 6428 395579 402007 Pleurisy; pleural effusion 5 507 1.0027 respiratory X 8213226 G A rs754602004 VCX2 9e-09 312 401593 401905 Sialolithiasis 2 528.7 1.0283 digestive 8 8902628 C T rs13282211 MFHAS1 9e-09 5217 367710 372927 Ulcer of esophagus 4 530.12 1.0166 digestive 10 107121516 A G rs570727188 SORCS1 9e-09 877 395835 396712 Chronic glomerulonephritis, NOS 3 580.14 1.0 genitourinary 15 71335261 C T rs1032032582 THSD4 9e-09 474 398897 399371 Traumatic amputation 2 872 0.97444 injuries & poisonings 15 54661980 A G rs750063825 UNC13C 9.1e-09 144 398705 398849 Disease of capillaries 6 448 1.0567 circulatory system 6 102611567 A G rs958908446 GRIK2 9.1e-09 3499 386241 389740 Hypotension NOS 3 458.9 1.0 circulatory system 8 10134226 A G rs76675074 MSRA 9.1e-09 2133 405035 407168 Abnormal sputum 4 516 1.0082 respiratory 6 55921063 T G rs895641 BMP5 9.1e-09 1927 393239 395166 Hammer toe (acquired) 5 735.21 1.011 musculoskeletal 20 59182140 G A rs531762960 ZNF831 9.2e-09 243 395582 395825 Pneumoconiosis 3 500.2 1.0166 respiratory 2 73825721 G A rs556550008 STAMBP 9.2e-09 493 389619 390112 Cholangitis 2 575.1 0.97444 digestive 2 222865562 G A rs115364606 ACSL3 9.3e-09 1637 392087 393724 Streptococcus infection 3 041.2 1.0082 infectious diseases 9 8173852 C T rs143467302 PTPRD 9.3e-09 54 404472 404526 Disturbances of sensation of smell and taste 2 350.6 0.95116 neurological 2 215261213 A T rs995051235 ATIC 9.3e-09 65 397694 397759 Other specified diffuse diseases of connective tissue 2 709.6 1.011 dermatologic 10 57001281 C A rs186777896 ZWINT 9.4e-09 1359 405102 406461 Inflammatory and toxic neuropathy 1 357 1.0054 neurological X 32788000 G A rs149537784 DMD 9.4e-09 60 400950 401010 Vitiligo 3 694.1 1.0 dermatologic 18 77319972 C T rs777022542 GALR1 9.5e-09 54 405056 405110 Cancer of the mouth floor 1 145.5 0.97444 neoplasms 6 13649822 C G rs572672194 RANBP9 9.5e-09 782 403145 403927 Other disorders of middle ear and mastoid 5 385 0.97444 sense organs 8 14607334 A G rs189323789 SGCZ 9.6e-09 5374 368847 374221 Secondary malignancy of lymph nodes 3 198.1 1.0082 neoplasms 14 52557778 A T rs745895793 GPR137C 9.6e-09 96 368848 368944 Neurofibromatosis 4 199.4 1.0254 neoplasms 7 14623268 C T rs528510510 DGKB 9.6e-09 1521 400114 401635 Lump or mass in breast 1 611.3 1.0054 genitourinary 2 237850822 C T rs1051807556 RBM44 9.6e-09 68 398898 398966 Open wound of neck 2 870.6 1.0254 injuries & poisonings 4 176414989 T C rs181293433 SPCS3 9.7e-09 114 392385 392499 Nerve plexus lesions 5 353.1 1.0704 neurological 7 68954262 T C rs765239505 AUTS2 9.7e-09 1493 400664 402157 Heart valve replaced 2 395.6 1.0082 circulatory system 19 37765810 C T rs141182067 ZNF573 9.9e-09 759 391483 392242 Cancer of esophagus 3 150 0.97444 neoplasms 2 70919243 A G rs1235771938 VAX2 9.9e-09 271 193708 193979 Cervical cancer 3 180.1 1.0437 neoplasms 4 112126473 C A rs768307423 FAM241A 9.9e-09 1164 401998 403162 Sleep disorders 2 327 1.0 neurological 13 55264356 T A rs544624334 PRR20A 9.9e-09 236 400950 401186 Other specified erythematous conditions 3 695.8 1.0501 dermatologic 5 63227943 C A rs145959387 IPO11 1e-08 938 201517 202455 Malignant neoplasm of ovary 2 184.11 0.97444 neoplasms 14 61094139 G A rs746493899 SLC38A6 1e-08 66 396288 396354 Abnormal weight gain 1 278.4 1.0254 endocrine/metabolic 6 142999252 G A rs557268763 HIVEP2 1e-08 1481 328788 330269 Elevated blood pressure reading without diagnosis of hypertension 3 402 1.0082 circulatory system 5 180293572 C T rs555252935 MAPK9 1e-08 832 404741 405573 Acute pharyngitis 1 465.2 0.97444 respiratory 5 15573289 TAG T rs144453295 FBXL7 1e-08 625 373884 374509 Bronchitis 5 497 0.97444 respiratory 12 5621174 G A rs576576061 ANO2 1e-08 153 406589 406742 Disorders of diaphragm 1 513.8 1.0669 respiratory X 142166530 A C rs143056761 MAGEC2 1e-08 830 333379 334209 Peritoneal or intestinal adhesions 2 560.3 0.97444 digestive 4 128818295 A G rs760048553 JADE1 1e-08 15316 333367 348683 Personal history of diseases of digestive system 5 564.9 1.0195 digestive 2 191399417 TTGTC T rs780129892 MYO1B 1e-08 209 398276 398485 Abnormal serum enzyme levels 3 573.9 1.0567 digestive 17 47886003 G A rs557214491 SP2 1e-08 138 378353 378491 Acute cystitis 3 592.11 1.0469 genitourinary 12 42102401 T G rs11181324 GXYLT1 1e-08 1125 393240 394365 Curvature of spine 3 737 1.0 musculoskeletal 15 101610000 C T rs139471332 TM2D3 1e-08 515 399563 400078 Pathologic fracture 3 743.2 0.97444 musculoskeletal 4 33398610 T C rs937027117 PCDH7 1e-08 109 406081 406190 Congenital musculoskeletal deformities of spine 3 754 1.0601 congenital anomalies 16 28842888 A G rs954404253 TUFM 1e-08 134 406506 406640 Nonspecific abnormal findings on radiological and other examination of musculoskeletal system 3 793 1.0635 symptoms 16 48302918 A G rs1048174236 LONP2 1e-08 1821 393231 395052 Complications of cardiac/vascular device, implant, and graft 5 854 1.0082 injuries & poisonings 16 54881483 T TAC rs879382827 IRX5 1e-08 250 403086 403336 Chronic dermatitis due to solar radiation 4 938.2 1.0469 injuries & poisonings X 116648146 A G rs201662384 CT83 1e-08 275 380140 380415 Anticoagulants causing adverse effects 3 964.1 1.0406 injuries & poisonings 9 86564072 G A rs7026807 TUT7 1.1e-08 848 392085 392933 Gram negative septicemia 2 038.1 0.97444 infectious diseases 8 4474309 G GA CSMD1 1.1e-08 272 404552 404824 Dermatophytosis 3 110.1 1.0406 infectious diseases 2 68445103 C G rs1355681621 FBXO48 1.1e-08 77 404729 404806 Rickets or osteomalacia 3 261.41 1.0283 endocrine/metabolic 4 90211365 C A rs977788381 CCSER1 1.1e-08 60 379216 379276 Other cardiac conduction disorders 3 426.8 1.0082 circulatory system 7 33543840 T A rs186249278 BBS9 1.1e-08 411 395582 395993 Lung disease due to external agents 3 500 1.0 respiratory 1 165022844 G A rs1382604784 PBX1 1.1e-08 388 401593 401981 Stomatitis and mucositis (ulcerative) 3 528.11 1.0 digestive 10 84828371 T C rs766788292 CCSER2 1.1e-08 15612 333376 348988 Noninfectious gastroenteritis 1 558 1.0224 digestive 13 46164447 G A rs1031440009 LCP1 1.1e-08 346 389621 389967 Nonspecific abnormal findings on radiological and other examination of biliary tract 2 575.9 1.0166 digestive 6 166922785 C T rs577135929 AL159163.1,RNASET2 1.1e-08 2649 395832 398481 Chronic renal failure [CKD] 5 585.3 1.0 genitourinary 5 127641571 A G rs78619674 CTXN3 1.1e-08 276 210936 211212 Inflammatory diseases of uterus, except cervix 1 614.4 1.0406 genitourinary 10 48630202 C T rs151106545 ARHGAP22 1.1e-08 176 397694 397870 Systemic sclerosis 4 709.3 1.0635 dermatologic 2 2915044 A G rs908316558 EIPR1 1.1e-08 9025 390235 399260 Intervertebral disc disorders 3 722 1.0283 musculoskeletal 12 10854477 T C rs757953619 AC018630.4,PRH1 1.1e-08 143 377179 377322 Contracture of tendon (sheath) 5 727.7 1.0669 musculoskeletal 12 24038706 C T rs1033417182 SOX5 1.1e-08 128 389419 389547 Costochondritis 1 733.6 1.0635 musculoskeletal 13 76447292 A C rs753674672 KCTD12 1.1e-08 1058 393240 394298 Kyphoscoliosis and scoliosis 2 737.3 1.0 musculoskeletal 5 57100472 G A rs193018057 GPBP1 1.1e-08 154 400908 401062 Difficulty in walking 1 741.3 1.0704 musculoskeletal 3 185663248 A G rs942085554 IGF2BP2 1.1e-08 191 405002 405193 Congenital anomalies of mouth/tongue 3 750.13 1.0469 congenital anomalies 4 181335125 T C rs190987936 TENM3 1.1e-08 717 386070 386787 Fracture of pelvis 1 802 0.97444 injuries & poisonings X 3606283 T C rs112145195 PRKX 1.1e-08 53 398898 398951 Open wound of hand except finger(s) 1 871.1 0.9298 injuries & poisonings 1 48688151 G A rs550096622 AGBL4 1.1e-08 229 398898 399127 Broken tooth 3 873 1.0501 injuries & poisonings X 116648146 A G rs201662384 CT83 1.1e-08 281 380140 380421 Poisoning by agents primarily affecting blood constituents 3 964 1.0406 injuries & poisonings 5 40354017 G A rs563942091 TTC33 1.2e-08 4234 402968 407202 Effects of other external causes 1 1015 1.0082 injuries & poisonings 8 4474309 G GA CSMD1 1.2e-08 278 404552 404830 Dermatophytosis / Dermatomycosis 3 110 1.0406 infectious diseases 1 220497146 AT A rs145644038 MARK1 1.2e-08 2664 368847 371511 Secondary malignant neoplasm of liver 2 198.4 1.0 neoplasms 6 119049555 AC A rs747553378 FAM184A 1.2e-08 1656 402713 404369 Leukemia 3 204 1.0082 neoplasms 6 10865150 A G rs3843518 AL024498.2 1.2e-08 370 405668 406038 Benign neoplasm of parathyroid gland 2 227.2 1.0054 neoplasms 15 49443100 T C rs4338740 FAM227B,FGF7 1.2e-08 91 389743 389834 Toxic multinodular goiter 6 242.2 1.0501 endocrine/metabolic 7 35938988 C T rs1281685185 SEPTIN7 1.2e-08 158 403660 403818 Other disorders of neurohypophysis 1 253.7 1.0601 endocrine/metabolic 17 53162660 G C rs750359857 KIF2B 1.2e-08 76 403660 403736 Hyperaldosteronism 3 255.12 1.0437 endocrine/metabolic 10 126641594 T C rs556526123 C10orf90 1.2e-08 202 404730 404932 Protein-calorie malnutrition 1 260 1.0534 endocrine/metabolic X 8479643 T C rs752395319 VCX3B 1.2e-08 113 399783 399896 Alkalosis 2 276.42 1.0601 endocrine/metabolic 1 193138899 C T rs374735931 CDC73 1.2e-08 361 363983 364344 Major depressive disorder 2 296.22 1.0166 mental disorders 3 112550102 GA G rs556021012 ATG3 1.2e-08 5031 393435 398466 Epilepsy, recurrent seizures, convulsions 1 345 1.0082 neurological 14 28294563 T C rs55641249 FOXG1 1.2e-08 285 397601 397886 Keratitis 3 370 1.0375 sense organs 10 48833238 G A rs909717688 WDFY4 1.2e-08 699 374655 375354 Aneurysm and dissection of heart 4 411.41 0.97444 circulatory system 1 110642337 C A rs146135657 KCNA2 1.2e-08 72 374656 374728 ASCVD 2 414.2 1.0313 circulatory system 11 46097317 T C rs1004675604 PHF21A 1.2e-08 1272 403885 405157 Cardiomyopathy 4 425 1.0 circulatory system 17 6010720 A G rs140306063 AC007846.2 1.2e-08 451 379216 379667 Second degree AV block 1 426.23 1.0 circulatory system 16 87861665 C T rs561708893 SLC7A5 1.2e-08 2111 400869 402980 Congestive heart failure (CHF) NOS 1 428.1 1.0 circulatory system 9 136437723 C T rs149976103 INPP5E 1.2e-08 548 388553 389101 Acute tonsillitis 1 474.1 0.97444 respiratory 9 1469384 C G rs980711906 DMRT2 1.2e-08 1132 395580 396712 Empyema and pneumothorax 2 506 1.0 respiratory 7 52279097 A G rs570237591 POM121L12 1.2e-08 110 396444 396554 Inflammatory conditions of jaw 3 526.5 1.0567 digestive 4 112809429 CA C rs772704982 ANK2 1.2e-08 6452 367705 374157 Dysphagia 4 532 1.011 digestive 12 43319879 T A rs900324584 ADAMTS20 1.2e-08 1651 383444 385095 Nonspecific abnormal findings in stool contents 3 579.8 1.0082 digestive 15 68913069 A C rs949906273 SPESP1 1.2e-08 1194 383295 384489 Dysuria 2 599.3 1.0 genitourinary 3 5468026 G A rs149194728 EDEM1 1.2e-08 62 383297 383359 Other symptoms involving urinary system 1 599.8 1.0195 genitourinary 1 56556005 T G rs765223462 PLPP3 1.2e-08 5716 210929 216645 Inflammatory diseases of female pelvic organs 2 614 1.0027 genitourinary 6 134755419 C T rs189373729 ALDH8A1 1.2e-08 1983 189131 191114 Irregular menstrual cycle 1 626.13 1.011 genitourinary 11 125573800 A G rs745918953 EI24,FEZ1 1.2e-08 306 218980 219286 Preeclampsia and eclampsia 2 642.1 1.0 pregnancy complications 7 121588475 T A rs771052573 FAM3C 1.2e-08 113 219790 219903 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium 5 649 1.0534 pregnancy complications 9 7252587 A C rs185776107 KDM4C 1.2e-08 554 364268 364822 Osteomyelitis 3 710.1 0.97444 musculoskeletal 5 73262831 C T rs189993452 TMEM174 1.2e-08 420 364270 364690 Arthropathy associated with infections 1 711 1.0 musculoskeletal 19 48311511 C T rs780998466 CCDC114 1.2e-08 332 400907 401239 Loose body in joint 1 742.1 1.0166 musculoskeletal 2 192317748 G A rs1459666074 TMEFF2 1.3e-08 2123 404550 406673 Candidiasis 2 112 1.0082 infectious diseases 8 62543294 C T rs749590784 NKAIN3 1.3e-08 580 402713 403293 Large cell lymphoma 4 202.24 0.97444 neoplasms 7 21898622 C A rs4487645 DNAH11 1.3e-08 554 402714 403268 Multiple myeloma 3 204.4 0.97444 neoplasms 10 86890603 T A rs12259628 BMPR1A 1.3e-08 160 407041 407201 Disorders of carbohydrate transport and metabolism 1 271 1.0635 endocrine/metabolic 2 115079152 G A rs1003489626 DPP10 1.3e-08 1159 399781 400940 Acid-base balance disorder 2 276.4 1.0 endocrine/metabolic 5 172544197 G A rs150990101 SH3PXD2B 1.3e-08 428 393433 393861 Cerebral degeneration, unspecified 2 331.9 1.0 neurological 14 73399502 G A rs144105862 NUMB 1.3e-08 212 397070 397282 Migrain with aura 1 340.1 1.0635 neurological 4 168267025 G A rs932819144 DDX60 1.3e-08 125 397601 397726 Eye infection, viral 2 369.2 1.0669 sense organs 10 7655989 T G rs771880022 ITIH5 1.3e-08 1412 399532 400944 Strabismus and other disorders of binocular eye movements 2 378 1.0082 sense organs 2 50423297 T C rs908156371 NRXN1 1.3e-08 227 397136 397363 Cerebral atherosclerosis 2 433.12 1.0534 circulatory system 20 61896063 GC G rs770358998 CDH4 1.3e-08 263 388552 388815 Paralysis/spasm of vocal cords or larynx 1 473.3 1.0437 respiratory 15 23195318 T C rs1263710357 GOLGA6L1 1.3e-08 1772 388555 390327 Acute and chronic tonsillitis 2 474 1.011 respiratory 11 124962305 G A rs181296821 CCDC15 1.3e-08 1460 395835 397295 Renal failure NOS 3 585.2 1.0027 genitourinary X 62729031 C A rs937235530 SPIN4 1.3e-08 72 400113 400185 Congenital anomalies of breast 16 612.3 1.0313 genitourinary 8 98560836 C T rs377639141 STK3 1.3e-08 273 210937 211210 Abscess or ulceration of vulva 6 614.54 1.0375 genitourinary 4 44027944 T G rs964116254 KCTD8 1.3e-08 72 207572 207644 Dysplasia of female genital organs 1 620 1.0344 genitourinary 6 87476117 G A rs544135215 AL049697.1,SLC35A1 1.3e-08 9072 189126 198198 Postmenopausal bleeding 2 627.1 1.0027 genitourinary 11 120810089 C T rs781310110 GRIK4 1.3e-08 78 397537 397615 Acne 1 706.1 1.0344 dermatologic 4 2836785 C G rs185045655 SH3BP2 1.3e-08 102 400908 401010 Ankylosis of joint 1 741.1 1.0601 musculoskeletal 12 2335259 A G rs1044975554 CACNA1C 1.3e-08 81 406081 406162 Congenital anomalies of muscle, tendon, fascia, and connective tissue 2 756.3 1.0344 congenital anomalies 12 80137257 C T rs752365751 OTOGL 1.3e-08 68 407134 407202 Bone marrow or stem cell transplant 1 860 1.0138 neoplasms 12 19787413 C A AEBP2 1.3e-08 104 403085 403189 Infusion and transfusion reaction 2 942 1.0437 injuries & poisonings 3 133886394 A C rs952913764 RAB6B 1.4e-08 9591 368847 378438 Secondary malignant neoplasm 7 198 1.0082 neoplasms 2 61426675 C T rs969604380 USP34 1.4e-08 289 399653 399942 Personal history of diseases of blood and blood-forming organs 2 289.3 1.0344 hematopoietic 2 148841035 T A rs573355915 KIF5C 1.4e-08 648 400597 401245 Delirium due to conditions classified elsewhere 8 290.2 0.97444 mental disorders 20 56380941 TG T rs545872011 AURKA 1.4e-08 178 363984 364162 Paranoid disorders 3 295.2 1.0635 mental disorders 10 59729009 G A rs932083229 SLC16A9 1.4e-08 169 363983 364152 Psychosis 2 295.3 1.0704 mental disorders 3 27652011 T A rs749894432 EOMES 1.4e-08 314 363985 364299 Tension headache 4 306.9 1.0224 mental disorders 8 28670402 T G rs764266920 EXTL3 1.4e-08 727 403915 404642 Diplopia and disorders of binocular vision 3 368.2 0.97444 sense organs 9 7127945 T A rs182940307 KDM4C 1.4e-08 275 400663 400938 Nonrheumatic aortic valve disorders 3 395.2 1.0406 circulatory system 4 67837059 A T rs553354942 TMPRSS11D 1.4e-08 3559 375933 379492 Precordial pain 2 418.1 1.0054 circulatory system 13 96512882 TTTG T rs926287723 HS6ST3 1.4e-08 2271 379217 381488 Cardiac pacemaker in situ 5 426.91 1.0054 circulatory system 6 32658661 A T rs9273367 HLA-DQB1 1.4e-08 383 398705 399088 Peripheral angiopathy in diseases classified elsewhere 3 443.7 1.0054 circulatory system 4 120459366 G A rs1481954769 PRDM5 1.4e-08 1054 333378 334432 Ulceration of the lower GI tract 7 556 1.0 digestive 2 190072000 T C rs967494971 C2orf88 1.4e-08 15904 333383 349287 Symptoms involving digestive system 2 561 1.0195 digestive 2 213416894 A G rs180760061 SPAG16 1.4e-08 74 395834 395908 Proliferative glomerulonephritis 2 580.11 1.0254 genitourinary X 81972489 G A rs1372029972 SH3BGRL 1.4e-08 208 395834 396042 Anatomical abnormatilies of kidney and ureters 14 586.1 1.0567 genitourinary 7 88731176 CTA C rs1290707332 ZNF804B 1.4e-08 774 399286 400060 Calculus of lower urinary tract 2 594.2 0.97444 genitourinary 11 39656242 C G rs554763794 LRRC4C 1.4e-08 120 400949 401069 Congenital anomalies of skin 2 691 1.0635 dermatologic 2 81727353 G A rs1195951617 CTNNA2 1.4e-08 78 406643 406721 Other specified congenital anomalies of nervous system 3 752.2 1.0406 congenital anomalies 4 184813353 A C rs757379214 ACSL1 1.4e-08 127 406643 406770 Congenital anomalies of the eye 1 753 1.0704 congenital anomalies 1 7391888 G A rs551182109 CAMTA1 1.4e-08 2958 403784 406742 Skull and face fracture and other intercranial injury 2 819 1.0027 injuries & poisonings 3 27145741 C A rs778975155 NEK10 1.4e-08 1949 380139 382088 Poisoning by psychotropic agents 4 969 1.0166 injuries & poisonings 7 4185521 C T rs879587225 SDK1 1.5e-08 117 401601 401718 HIV infection, symptomatic 2 071.1 1.0669 infectious diseases 4 134054649 C G rs990504591 PABPC4L 1.5e-08 255 406947 407202 Injury to blood vessels 3 1007 1.0469 injuries & poisonings 1 103762024 A G rs528415879 AMY1C 1.5e-08 220 192375 192595 Benign neoplasm of other female genital organs 3 221 1.0601 neoplasms 1 35981583 A G rs1197957910 AGO3 1.5e-08 446 404730 405176 Vitamin D deficiency 4 261.4 1.0 endocrine/metabolic 11 68907461 G A rs533268912 IGHMBP2 1.5e-08 84 396287 396371 Localized adiposity 1 278.3 1.0406 endocrine/metabolic 2 115888039 G A rs186852223 DPP10 1.5e-08 418 404524 404942 Primary thrombocytopenia 1 287.31 1.0 hematopoietic 1 198706633 T G rs1374484177 PTPRC 1.5e-08 123 363984 364107 Somatoform disorder 2 303.4 1.0704 mental disorders 5 103067219 T C rs572200003 GIN1 1.5e-08 28652 363984 392636 Other mental disorder 4 306 1.0775 mental disorders 20 23732690 T A rs1013282080 CST1 1.5e-08 76 406624 406700 Pervasive developmental disorders 1 313 1.0283 mental disorders 11 80414322 G A rs747666141 TENM4 1.5e-08 469 405101 405570 Muscular dystrophies and other myopathies 6 359 1.0 neurological 2 136700984 C T rs559694014 THSD7B 1.5e-08 154 403915 404069 Anisometropia 2 368.3 1.0601 sense organs 2 163848453 G T rs146446878 FIGN 1.5e-08 4904 400663 405567 Rheumatic disease of the heart valves 3 394 1.0082 circulatory system 1 60042256 C T rs138742743 C1orf87 1.5e-08 600 400269 400869 Chronic pulmonary heart disease 2 415.2 0.97444 circulatory system 1 108789067 A T rs745998062 STXBP3 1.5e-08 6919 379218 386137 Cardiac conduction disorders 3 426 1.0082 circulatory system 12 6541950 A T rs145222821 IFFO1 1.5e-08 534 379217 379751 Premature beats 5 427.6 0.97444 circulatory system 4 75847163 C T rs1018940086 PPEF2 1.5e-08 393 397139 397532 Cerebral aneurysm 2 433.5 1.0082 circulatory system 3 7264795 C T rs1472730266 GRM7 1.5e-08 1334 386242 387576 Orthostatic hypotension 3 458.1 1.0027 circulatory system 3 155207354 T G rs898123836 MME 1.5e-08 1996 395580 397576 Pulmonary collapse; interstitial and compensatory emphysema 1 508 1.0138 respiratory 10 27203705 C A rs185590948 ACBD5 1.5e-08 83 406590 406673 Hypoventilation 5 513.3 1.0254 respiratory 12 72253031 G A rs756599780 TRHDE 1.5e-08 1171 396444 397615 Periapical abscess 1 522.5 1.0 digestive 20 540438 G A rs748085265 CSNK2A1 1.5e-08 304 396444 396748 Anomalies of tooth position/malocclusion 1 524.3 1.0313 digestive 8 71720812 T A rs111519225 MSC 1.5e-08 635 367706 368341 Disorders of esophageal motility 3 530.5 0.97444 digestive 10 7246516 C T rs1049659521 SFMBT2 1.5e-08 21937 333366 355303 Functional digestive disorders 2 564 1.0283 digestive X 36652642 A T rs189764780 CFAP47 1.5e-08 1542 398276 399818 Ascites (non malignant) 1 572 1.011 digestive 10 17720061 C T rs770264229 STAM 1.5e-08 3443 207568 211011 Mucous polyp of cervix 1 622.2 1.0027 genitourinary 9 32109220 C T rs1025171189 ACO1 1.5e-08 63 219608 219671 Other disorders of the breast associated with childbirth and disorders of lactation 3 676 1.0027 pregnancy complications 10 23643648 G GT rs5783852 KIAA1217 1.5e-08 397 364269 364666 Unspecified osteomyelitis 1 710.19 1.0054 musculoskeletal 20 51047331 A G rs1007356051 KCNG1 1.5e-08 63 390234 390297 Other symptoms referable to back 1 724.8 1.0138 musculoskeletal 4 183656957 C T rs746473126 RWDD4 1.5e-08 356 405001 405357 Lower gastrointestinal congenital anomalies 1 750.2 1.011 congenital anomalies 7 16263050 T A rs901509518 CRPPA 1.5e-08 118 405001 405119 Congenital anomaly of gallbladder, bile ducts, liver, pancreas 5 750.22 1.0567 congenital anomalies 14 77688604 G A ALKBH1 1.5e-08 564 406508 407072 Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc) 2 793.2 0.97444 symptoms 17 67670887 G C rs118118589 PITPNC1 1.5e-08 773 386069 386842 Fracture of ribs 2 807 0.97444 injuries & poisonings 14 87995873 C G rs1026287485 GALC 1.5e-08 1668 383454 385122 Torus fracture 2 823 1.0054 injuries & poisonings 8 18857521 A C rs918727245 PSD3 1.6e-08 102 403659 403761 Iatrogenic endocrine disorders 2 258 1.0601 endocrine/metabolic 11 27914994 A C rs149999049 KIF18A 1.6e-08 612 403455 404067 Crystal arthropathies 2 274.2 0.97444 endocrine/metabolic 2 37366911 T C rs142235232 QPCT 1.6e-08 6342 363982 370324 Anxiety disorder 4 300.1 1.0166 mental disorders 17 73936891 T C rs537869025 RPL38 1.6e-08 502 393432 393934 Hydrocephalus 1 331.1 0.97444 neurological 3 177962442 AT A rs758115504 KCNMB2 1.6e-08 864 393433 394297 Epilepsy 5 345.1 0.97444 neurological 2 183818763 G A rs779346484 NUP35 1.6e-08 201 396051 396252 Corneal degenerations 3 364.4 1.0601 sense organs 7 104469942 A G rs9969202 LHFPL3 1.6e-08 305 213272 213577 Fibroadenosis of breast 1 610.2 1.0283 genitourinary 3 164198770 T C rs766056044 SI 1.6e-08 427 210937 211364 Vaginitis and vulvovaginitis 3 614.52 0.97444 genitourinary 10 70512515 A G rs768148737 PALD1 1.6e-08 864 212251 213115 Antepartum hemorrhage, abruptio placentae, and placenta previa 2 635.2 1.0 pregnancy complications 17 44890174 T C rs765217342 EFTUD2 1.6e-08 411 377181 377592 Laxity of ligament or hypermobility syndrome 2 728.2 1.0 musculoskeletal 7 77337395 G A rs893884792 GSAP 1.6e-08 1168 403747 404915 Neuralgia, neuritis, and radiculitis NOS 5 766 1.0027 symptoms 4 163587416 G A rs189929918 MARCHF1 1.6e-08 475 380140 380615 Antirheumatics causing adverse effects in therapeutic use 2 965.2 1.0 injuries & poisonings 5 78687054 A C rs1004157201 LHFPL2 1.6e-08 403 380139 380542 Salicylates causing adverse effects in therapeutic use 1 965.3 1.0082 injuries & poisonings 10 76195784 C T rs775148567 LRMDA 1.6e-08 84 380139 380223 Antihypertensive agents causing adverse effects 2 972.6 1.0437 injuries & poisonings 7 117303470 A G rs62469413 CFTR,WNT2 1.7e-08 69 401601 401670 Viral hepatitis A 2 070.1 1.0254 infectious diseases 4 136419402 G A rs536107175 PCDH18 1.7e-08 132 401601 401733 Viral hepatitis B 3 070.2 1.0601 infectious diseases 1 68135127 CTTTCT C WLS 1.7e-08 641 405055 405696 Cancer of mouth 2 145 0.97444 neoplasms 6 137563634 C A rs997049728 OLIG3 1.7e-08 1032 403024 404056 Malignant neoplasm of kidney, except pelvis 1 189.11 1.0 neoplasms 20 33455947 G A rs73622511 SNTA1 1.7e-08 17123 368844 385967 Cancer, suspected or other 4 195 1.0138 neoplasms 8 28745887 CTG C rs772325867 EXTL3 1.7e-08 85 388395 388480 Other hereditary hemolytic anemias 2 282.9 1.0437 hematopoietic 6 50911369 G C rs937545535 TFAP2B 1.7e-08 252 393433 393685 Other demyelinating diseases of central nervous system 3 341 1.0437 neurological 8 70041633 T G rs950460147 PRDM14 1.7e-08 4192 402829 407021 Hearing loss 1 389 1.0082 sense organs 11 126674231 T C rs999885526 KIRREL3 1.7e-08 2600 395581 398181 Respiratory failure, insufficiency, arrest 1 509 1.0027 respiratory 9 118096041 C T rs746815972 AL160272.2 1.7e-08 220 398129 398349 Wheezing 1 512.1 1.0534 respiratory 10 65970381 A C rs1228043872 CTNNA3 1.7e-08 61 396444 396505 Anomalies of jaw size/symmetry 2 526.3 1.0 digestive X 54693187 C T rs183193336 ITIH6 1.7e-08 179 401591 401770 Cellulitis and abscess of oral soft tissues 1 528.3 1.0601 digestive 8 123550572 T A rs551457629 FBXO32 1.7e-08 59 169003 169062 Orchitis and epididymitis 2 601.3 0.97444 genitourinary 7 14623268 C T rs528510510 DGKB 1.7e-08 1572 400114 401686 Abnormal findings on mammogram or breast exam 1 611 1.011 genitourinary 17 76501986 A C rs4789306 RHBDF2 1.7e-08 616 212247 212863 Early onset of delivery 1 636.2 1.0 pregnancy complications 7 25725724 A G rs763693378 NFE2L3 1.7e-08 583 395973 396556 Pilonidal cyst 1 686.3 0.97444 dermatologic 5 115805650 C T rs1468868009 CDO1 1.7e-08 428 405002 405430 Cystic kidney disease 3 751.21 1.0 congenital anomalies 2 126128858 G C rs535728551 GYPC 1.7e-08 270 380139 380409 Poisoning by agents primarily affecting the cardiovascular system 3 972 1.0406 injuries & poisonings 6 146099860 C T rs776618676 GRM1 1.8e-08 417 387083 387500 Other abnormal glucose 11 250.42 1.0027 endocrine/metabolic 6 32658661 A T rs9273367 HLA-DQB1 1.8e-08 7627 388399 396026 Iron deficiency anemias 3 280 1.0138 hematopoietic X 73660157 A G rs59548312 CHIC1 1.8e-08 501 363983 364484 Phobia 6 300.13 0.97444 mental disorders 1 181683153 AGCAAGGGCATCTTAT A rs1267707000 CACNA1E 1.8e-08 79 396051 396130 Corneal edema 6 364.2 1.0406 sense organs 9 72242420 A G rs144028364 GDA 1.8e-08 102 398705 398807 Aneurysm of iliac artery 3 442.2 1.0567 circulatory system 13 42863397 G T rs17537837 EPSTI1 1.8e-08 184 367907 368091 Chronic venous insufficiency [CVI] 2 456 1.0704 circulatory system 13 47194806 G A rs73178157 HTR2A 1.8e-08 2554 388552 391106 Diseases of the larynx and vocal cords 4 473 1.0 respiratory 12 101208490 G C rs141008504 SLC5A8 1.8e-08 307 401593 401900 Leukoplakia of oral mucosa 6 528.6 1.0313 digestive 19 39681918 G C rs984389572 LGALS16 1.8e-08 515 404504 405019 Chronic pancreatitis 1 577.2 0.97444 digestive 7 29906560 A G rs980397966 WIPF3 1.8e-08 364 404503 404867 Cyst and pseudocyst of pancreas 2 577.3 1.011 digestive 10 121288494 A G rs10886900 FGFR2 1.8e-08 6725 383302 390027 Retention of urine 3 599.2 1.0082 genitourinary 16 27576592 G A rs956849513 KATNIP 1.8e-08 519 395970 396489 Cellulitis and abscess of face/neck 1 681.2 0.97444 dermatologic 5 178783688 C T rs988003949 ZNF354A 1.8e-08 2283 395970 398253 Carbuncle and furuncle 4 686.1 1.011 dermatologic 1 202683363 A G rs6673562 SYT2 1.8e-08 869 401762 402631 Musculoskeletal symptoms referable to limbs 2 771 0.97444 symptoms 11 120972879 G C rs528526760 GRIK4 1.8e-08 1312 405742 407054 Injuries to the nervous system 2 907 1.0027 injuries & poisonings 5 126828763 A G rs969615527 LMNB1 1.9e-08 315 406887 407202 Asphyxia and hypoxemia 3 1013 1.0254 injuries & poisonings 4 47969761 C T rs756981290 CNGA1,NIPAL1 1.9e-08 1062 391483 392545 Neoplasm of unspecified nature of digestive system 1 158 1.0 neoplasms 2 21930144 T C rs114041745 TDRD15 1.9e-08 1595 405607 407202 Hemangioma and lymphangioma, any site 1 228 1.0082 neoplasms 2 168454228 G A rs62175786 CERS6 1.9e-08 828 404732 405560 Anorexia 1 260.6 0.97444 endocrine/metabolic 10 131883825 C T rs1428144950 PPP2R2D 1.9e-08 135 388395 388530 Acquired hemolytic anemias 3 283 1.0669 hematopoietic 9 137915137 C T rs971276878 CACNA1B 1.9e-08 192 405102 405294 Myasthenia gravis 1 358.1 1.0635 neurological 6 105693815 G A rs149561781 PREP 1.9e-08 100 396050 396150 Cornea replaced by transplant 4 364.9 1.0501 sense organs 16 55238038 C T rs374190943 IRX6 1.9e-08 5692 397601 403293 Other disorders of eyelids 2 374 1.0082 sense organs X 141927968 T A rs778517021 MAGEC1 1.9e-08 2887 400662 403549 Nonrheumatic mitral valve disorders 3 395.1 1.0027 circulatory system 3 180186908 CTG C rs1286306356 PEX5L 1.9e-08 3200 379212 382412 Paroxysmal tachycardia, unspecified 1 427.1 1.0 circulatory system 8 104372885 T A rs6468922 DPYS 1.9e-08 521 333379 333900 Paralytic ileus 1 560.1 0.97444 digestive 6 6429169 A G rs1462770866 F13A1 1.9e-08 2547 212190 214737 Complications of labor and delivery NEC 2 669 0.97444 pregnancy complications 1 114083540 G A rs760659672 SYT6 1.9e-08 290 402139 402429 Corns and callosities 3 700 1.0375 dermatologic X 5926316 T C rs1340021444 NLGN4X 1.9e-08 61 402139 402200 Circumscribed scleroderma 1 701.3 0.95116 dermatologic 14 38964379 G A rs1004659806 SEC23A 1.9e-08 81 364269 364350 Infective connective tissue disorders 1 712 1.0469 musculoskeletal 2 16851745 G A rs12052369 CYRIA 1.9e-08 302 406848 407150 Congenital anomalies of face and neck 4 749 1.0283 congenital anomalies 4 90872832 TTGTC T rs965099051 CCSER1 1.9e-08 686 405001 405687 Digestive congenital anomalies 2 750 0.97444 congenital anomalies 8 29516563 C G rs746722557 DUSP4 1.9e-08 252 406644 406896 Neural tube defects 1 752.1 1.0469 congenital anomalies 17 68752727 T G rs569830324 ABCA8 1.9e-08 524 389790 390314 Traumatic arthropathy 1 836 0.97444 injuries & poisonings 2 17064070 C T rs879609211 CYRIA 1.9e-08 419 380139 380558 Poisoning by other anti-infectives 2 961 1.0 injuries & poisonings 9 22734116 G A rs563545525 DMRTA1 2e-08 60 404341 404401 Cancer of intrathoracic organs 3 164 0.95116 neoplasms 3 169016593 T C rs966412411 MECOM 2e-08 264 387082 387346 Impaired fasting glucose 5 250.41 1.0406 endocrine/metabolic 14 85525661 AT A rs766430464 FLRT2 2e-08 238 218078 218316 Ovarian dysfunction 1 256 1.0437 endocrine/metabolic 10 54226887 T C rs767952994 PCDH15 2e-08 152 185582 185734 Testicular hypofunction 3 257.1 1.0669 endocrine/metabolic 6 166231779 T A rs377575227 TBXT 2e-08 707 363984 364691 Agorophobia, social phobia, and panic disorder 1 300.12 0.97444 mental disorders 16 83761862 T G rs1020647204 CDH13 2e-08 341 406121 406462 Encephalitis 2 323 1.0224 neurological 15 93272815 T G rs113907512 RGMA 2e-08 252 393433 393685 Torsion dystonia 4 333.4 1.0406 neurological 14 60698568 G A rs544609727 SIX4 2e-08 152 405102 405254 Hereditary and idiopathic peripheral neuropathy 2 356 1.0669 neurological 4 97223693 A G rs959436731 STPG2 2e-08 213 397602 397815 Conjunctivitis, infectious 2 369.5 1.0534 sense organs 9 133822857 G A rs1221261438 VAV2 2e-08 849 403146 403995 Suppurative and unspecified otitis media 4 381.11 0.97444 sense organs 4 41864097 TG T rs1240177536 TMEM33 2e-08 144 328788 328932 Other hypertensive complications 3 401.3 1.0704 circulatory system 5 176702531 G A rs182024143 TSPAN17 2e-08 223 403885 404108 Acute pericarditis 2 420.21 1.0534 circulatory system 10 130925747 TGTGA T rs554821273 TCERG1L 2e-08 165 404739 404904 Acute laryngitis and tracheitis 2 465.4 1.0601 respiratory 10 91470823 A G rs551506529 HECTD2 2e-08 325 397697 398022 Respiratory complications 1 519.2 1.0224 respiratory 9 116714572 C T rs10115816 ASTN2 2e-08 165 378352 378517 Urethritis and urethral syndrome 1 592.2 1.0669 genitourinary 2 44967241 G T rs765820342 SIX3 2e-08 702 405230 405932 Other signs and symptoms in breast 2 613.7 0.97444 genitourinary 22 45806218 G A rs753406772 ATXN10 2e-08 562 395971 396533 Cellulitis and abscess of fingers/toes 1 681.1 0.97444 dermatologic X 88615167 A T rs1408484819 CPXCR1 2e-08 109 400950 401059 Toxic erythema 6 695.1 1.0635 dermatologic 1 87616327 G A rs1051017208 LMO4 2e-08 87 402139 402226 Keratoderma, acquired 4 701.1 1.0469 dermatologic 4 104464476 G C rs775030803 CXXC4 2e-08 539 389420 389959 Aseptic necrosis of bone 1 733.4 0.97444 musculoskeletal 1 239098827 T C rs79997883 CHRM3 2e-08 9676 393237 402913 Acquired foot deformities 3 735 1.0344 musculoskeletal 15 91758860 G A rs984892797 SLCO3A1 2e-08 248 393237 393485 Acquired deformities of finger 1 736.2 1.0501 musculoskeletal 13 48422123 C T rs548315622 LPAR6,RB1 2e-08 3154 393231 396385 Complication of internal orthopedic device 4 858 1.0 injuries & poisonings 15 95180917 ATATT A rs1413548012 MCTP2 2.1e-08 110 180551 180661 Neoplasm of uncertain behavior of male genital organs 1 187.8 1.0704 neoplasms 6 137563634 C A rs997049728 OLIG3 2.1e-08 1072 403023 404095 Cancer of kidney and renal pelvis 1 189.1 1.0 neoplasms 10 118218720 G A rs552431943 FAM204A 2.1e-08 357 393433 393790 Coma 2 348.7 1.0166 neurological 2 183531283 G C rs77999150 NUP35 2.1e-08 1060 397601 398661 Ectropion or entropion 2 374.1 1.0 sense organs 1 217322592 A C rs1342414152 GPATCH2 2.1e-08 1541 328788 330329 Hypertensive chronic kidney disease 1 401.22 1.0082 circulatory system 13 91672789 T A rs1039198191 GPC5 2.1e-08 29134 375932 405066 Nonspecific chest pain 2 418 1.0567 circulatory system 4 169740211 G A rs747933910 HPF1 2.1e-08 343 379217 379560 Ventricular fibrillation and flutter 1 427.41 1.0195 circulatory system 9 2947656 TAGAC T rs1212128294 PUM3 2.1e-08 2279 404741 407020 Acute upper respiratory infections of multiple or unspecified sites 2 465 1.0082 respiratory 9 90041779 C T rs147192059 GADD45G 2.1e-08 377 388554 388931 Throat pain 1 478 1.0 respiratory 1 48844830 G A rs527498849 AGBL4 2.1e-08 233 396443 396676 Jaw disease NOS 1 526.9 1.0534 digestive 1 221878992 TA T rs1471509682 DUSP10 2.1e-08 94 401593 401687 Cyst of the salivary gland 3 528.41 1.0534 digestive 2 9938002 C T rs562437242 TAF1B 2.1e-08 5523 333379 338902 Irritable Bowel Syndrome 1 564.1 1.0138 digestive 1 96971697 A C rs748438313 DPYD 2.1e-08 1127 207571 208698 Endometrial hyperplasia 2 621 1.0 genitourinary 11 131217122 C T rs188640329 NTM 2.1e-08 52 220036 220088 Complications of in utero procedures 5 679 0.97444 dermatologic 12 48807222 A G rs2453480 CACNB3 2.1e-08 2144 401682 403826 Rash and other nonspecific skin eruption 1 687.1 1.0082 dermatologic 3 154820902 GA G rs1434461185 MME 2.1e-08 1990 400905 402895 Other derangement of joint 1 742.9 1.011 musculoskeletal 11 30521553 A G rs546292489 MPPED2 2.1e-08 84 400617 400701 Elevated sedimentation rate 1 790.1 1.0469 symptoms 2 192768939 C T rs773752439 TMEFF2 2.1e-08 548 406654 407202 Gangrene 1 791 0.97444 symptoms 15 57001004 T A rs1025735342 TCF12 2.1e-08 120 407082 407202 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) 4 794 1.0567 symptoms 5 65375703 C T rs1370795633 ADAMTS6 2.1e-08 157 393231 393388 Complications of transplants and reattached limbs 1 851 1.0669 injuries & poisonings 20 18067437 C G rs1048568591 OVOL2 2.2e-08 1444 405758 407202 Other symptoms 2 1005 1.0082 injuries & poisonings 1 6944881 C T rs759788099 CAMTA1 2.2e-08 193 391483 391676 Malignant neoplasm of retroperitoneum and peritoneum 3 159.4 1.0601 neoplasms 10 45699220 G A rs4042203 ZFAND4 2.2e-08 129 405449 405578 Benign neoplasm of eye 2 224 1.0669 neoplasms 2 197971473 C T rs114640810 PLCL1 2.2e-08 101 389742 389843 Acquired hypothyroidism 2 244.2 1.0567 endocrine/metabolic 8 24909532 C CA NEFM 2.2e-08 657 393433 394090 Other paralytic syndromes 3 344 0.97444 neurological 9 137915137 C T rs971276878 CACNA1B 2.2e-08 211 405102 405313 Myoneural disorders 1 358 1.0567 neurological 3 4065340 A G rs1359205305 SUMF1 2.2e-08 1279 400663 401942 Aortic valve disease 2 394.3 1.0027 circulatory system 3 180668425 G A rs13097883 CCDC39 2.2e-08 207 398129 398336 Painful respiration 2 512.2 1.0635 respiratory 12 59209449 A T rs948884625 LRIG3 2.2e-08 2464 404713 407177 Abnormal findings examination of lungs 2 514 1.0027 respiratory 6 53138320 G A rs540949092 GCM1 2.2e-08 2035 396444 398479 Disorders of tooth development 2 520 1.0054 digestive 12 38768243 T G rs771008031 CPNE8 2.2e-08 22959 367715 390674 GERD 6 530.11 1.0534 digestive 2 159143239 G A rs745993043 TANC1 2.2e-08 4095 399770 403865 Gastric ulcer 1 531.2 1.0082 digestive 2 207955801 A G rs765818519 PLEKHM3 2.2e-08 2624 383440 386064 Blood in stool 3 578.2 1.0027 digestive 22 38000067 G A rs983280556 POLR2F 2.2e-08 1950 405245 407195 Chronic ulcer of skin 4 707 1.011 dermatologic 1 239594014 A G rs758782307 CHRM3 2.2e-08 189 390234 390423 Spondylosis with myelopathy 1 721.2 1.0601 musculoskeletal 3 173072826 A G rs1043207286 SPATA16 2.2e-08 1687 386070 387757 Fracture of humerus 3 803.1 1.011 injuries & poisonings 2 179922932 T G rs551201384 CWC22 2.3e-08 4174 392084 396258 Septicemia 1 038 1.0 infectious diseases 7 73635115 T C rs1037743002 MLXIPL 2.3e-08 95 401601 401696 Herpes zoster with nervous system complications 4 053.1 1.0534 infectious diseases 2 22662321 G A rs112833363 KLHL29 2.3e-08 71 407129 407200 Sexually transmitted infections (not HIV or hepatitis) 2 090 1.0254 infectious diseases 8 71587650 G A rs576028235 EYA1 2.3e-08 1106 399894 401000 Other benign neoplasm of connective and other soft tissue 2 215 1.0 neoplasms 18 84562 C T rs759506626 TUBB8B 2.3e-08 594 398901 399495 Nevus, non-neoplastic 2 217.1 0.97444 neoplasms 9 113704407 T C rs962236028 RGS3 2.3e-08 355 203949 204304 Other benign neoplasm of uterus 2 218.2 1.0054 neoplasms 3 144399971 T C rs772499165 DIPK2A 2.3e-08 104 387082 387186 Type 2 diabetes with ketoacidosis 1 250.21 1.0567 endocrine/metabolic 12 110782167 G A rs904467415 PPP1CC 2.3e-08 124 363984 364108 Acute reaction to stress 5 300.8 1.0669 mental disorders 5 36748379 C T rs186225833 SLC1A3 2.3e-08 333 363985 364318 Personality disorders 2 301 1.0224 mental disorders 18 38366651 G A rs191927845 CELF4 2.3e-08 162 406624 406786 Learning disorder 5 315.1 1.0669 mental disorders 10 65709549 T C rs1393626768 CTNNA3 2.3e-08 7848 397073 404921 Other headache syndromes 3 339 1.0138 neurological 2 130188903 A C rs574534076 MZT2B 2.3e-08 102 386959 387061 Traumatic cataract 2 366.3 1.0567 sense organs X 148935689 C T rs192306070 AFF2 2.3e-08 241 403146 403387 Tympanosclerosis and middle ear disease related to otitis media 3 385.5 1.0437 sense organs 2 156990967 T C rs756321415 GALNT5 2.3e-08 3817 379214 383031 Palpitations 4 427.9 1.0027 circulatory system 6 87858684 G C rs763532149 AKIRIN2 2.3e-08 266 397137 397403 Subdural hemorrhage 3 430.3 1.0344 circulatory system 12 11289101 G C rs978532933 PRB4 2.3e-08 99 396438 396537 Pneumonia due to fungus (mycoses) 1 480.3 1.0534 respiratory 15 64730998 C G rs550152487 RBPMS2 2.3e-08 1764 210808 212572 Noninflammatory disorders of vagina 3 619.4 1.011 genitourinary 8 52393191 A G rs1353715545 ST18 2.3e-08 1529 405004 406533 Genitourinary congenital anomalies 1 751 1.011 congenital anomalies 12 42483961 C T rs977022493 PRICKLE1 2.3e-08 105 406579 406684 Toxic effect of other gases, fumes, or vapors 3 987 1.0635 injuries & poisonings 15 69303730 T C rs1393849 PAQR5 2.4e-08 1282 193769 195051 Malignant neoplasm of uterus 3 182 1.0 neoplasms 14 34127318 G A rs145643129 EGLN3 2.4e-08 210 389743 389953 Chronic lymphocytic thyroiditis 1 245.21 1.0469 endocrine/metabolic 3 170006184 T C rs918080510 SEC62 2.4e-08 437 400600 401037 Alteration of consciousness 2 291.8 1.0 mental disorders 8 78181782 T TA PKIA 2.4e-08 717 404787 405504 Blindness and low vision 5 367.9 0.97444 sense organs 12 86925999 C T rs190906260 MGAT4C 2.4e-08 201 402827 403028 Other disorders of ear 1 388 1.0601 sense organs 7 53656969 A G rs761949338 POM121L12 2.4e-08 3337 379218 382555 Bundle branch block 2 426.3 1.0 circulatory system 10 115082303 G T rs782171697 ATRNL1 2.4e-08 2896 397142 400038 Cerebral ischemia 1 433.3 1.0 circulatory system 4 145186075 T A rs948695951 OTUD4 2.4e-08 327 396439 396766 Influenza 1 481 1.0224 respiratory 1 114169342 T C rs148308163 SYT6 2.4e-08 296 398277 398573 Hepatomegaly 1 573.3 1.0313 digestive 22 48904824 G A rs769274970 TAFA5 2.4e-08 248 378354 378602 Chronic interstitial cystitis 2 592.13 1.0437 genitourinary 13 61941133 G A rs7985450 AL592490.1 2.4e-08 10427 189128 199555 Menopausal and postmenopausal disorders 2 627 1.0027 genitourinary 10 59185743 G T rs917652821 PHYHIPL 2.4e-08 1109 189127 190236 Postmenopausal atrophic vaginitis 1 627.3 0.97444 genitourinary 19 49227467 G A rs373211988 TRPM4 2.4e-08 330 212249 212579 Ectopic pregnancy 2 634.3 1.0027 pregnancy complications 1 17395297 G A rs973839415 PADI6 2.4e-08 117 400950 401067 Vascular disorders of skin 2 694.3 1.0669 dermatologic 9 16309276 A G rs73645941 BNC2 2.4e-08 907 405244 406151 Decubitus ulcer 1 707.1 0.97444 dermatologic 11 113962914 A G rs888051278 HTR3A 2.4e-08 2843 400905 403748 Derangement of joint, non-traumatic 1 742 1.0 musculoskeletal 21 25536399 T C rs751752291 MRPL39 2.4e-08 7999 399203 407202 Pain in joint 1 745 1.0138 musculoskeletal 7 94230443 C A rs1299652819 COL1A2 2.4e-08 196 398896 399092 Open wound of ear 6 870.2 1.0635 injuries & poisonings 21 38320831 G A rs576550266 KCNJ15 2.5e-08 158 391483 391641 Malignant neoplasm of liver, primary 1 155.1 1.0669 neoplasms 6 157354779 G A rs587654780 ZDHHC14 2.5e-08 814 405448 406262 Benign neoplasm of brain and other parts of nervous system 5 225 0.97444 neoplasms 20 45779554 C A rs1301526824 WFDC3 2.5e-08 96 393432 393528 Myoclonus 4 333.2 1.0501 neurological 22 23063519 G A rs1222897666 RSPH14 2.5e-08 68 396051 396119 Retinoschisis and retinal cysts 4 361.2 1.0 sense organs 5 3016217 A T rs12655710 C5orf38 2.5e-08 1044 400664 401708 Abnormal heart sounds 3 396 1.0 circulatory system 3 85789791 C A rs536821221 CADM2 2.5e-08 2684 400268 402952 Cardiomegaly 6 416 1.0 circulatory system 14 64829350 T C rs118064147 SPTB 2.5e-08 1053 388552 389605 Allergic rhinitis 3 476 1.0 respiratory 12 2103063 A G rs1252825260 CACNA1C 2.5e-08 179 395834 396013 Small kidney 5 586.11 1.0601 genitourinary 4 65038477 G T rs1301772731 EPHA5 2.5e-08 76 400950 401026 Erythema nodosum 2 695.81 1.0375 dermatologic 8 46066914 G T rs568283481 SPIDR 2.5e-08 1416 400907 402323 Joint effusions 2 741.4 1.0027 musculoskeletal 14 43793043 A G rs150330032 FSCB 2.5e-08 424 406082 406506 Congenital anomalies of limbs 2 755 1.0 congenital anomalies 7 146785436 A G rs527305867 CNTNAP2 2.5e-08 96 406232 406328 Anomalies of endocrine glands, congenital 2 759.1 1.0501 congenital anomalies 20 47769931 C T rs80122879 SULF2 2.5e-08 3413 403789 407202 Malaise and fatigue 1 798 1.0054 symptoms 7 40192524 C T rs1406495219 SUGCT 2.5e-08 468 406669 407137 Sprains and strains 4 840 1.0 injuries & poisonings 5 110033156 G A rs147733960 MAN2A1 2.5e-08 1448 405754 407202 Contusion 3 916 1.0027 injuries & poisonings 16 48055628 C T rs537253472 ABCC12 2.5e-08 396 403085 403481 Allergies, other 3 949 1.0027 injuries & poisonings 2 80198577 T C rs979419242 CTNNA2 2.6e-08 574 363984 364558 Schizophrenia 2 295.1 0.97444 mental disorders X 142535591 C G rs185067397 MAGEC2 2.6e-08 99 395155 395254 Separation of retinal layers 1 362.31 1.0534 sense organs 12 102404723 G A rs771356833 IGF1 2.6e-08 331 403916 404247 Visual field defects 1 368.4 1.0195 sense organs 4 174885771 T C rs1342481803 ADAM29 2.6e-08 1040 403146 404186 Perforation of tympanic membrane 4 384.4 1.0 sense organs X 141927968 T A rs778517021 MAGEC1 2.6e-08 2991 400662 403653 Mitral valve disease 3 394.2 1.0027 circulatory system 8 139929497 A C rs115488727 TRAPPC9 2.6e-08 93 396437 396530 Pseudomonal pneumonia 2 480.12 1.0469 respiratory 5 677233 T C rs35914637 TPPP 2.6e-08 10498 367713 378211 Reflux esophagitis 2 530.14 1.0224 digestive 1 35331878 A AT rs773768600 ZMYM4 2.6e-08 887 378355 379242 Chronic cystitis 3 592.12 1.0 genitourinary 9 132338262 T C rs751684045 SETX 2.6e-08 277 167467 167744 Erectile dysfunction [ED] 2 605 1.0166 genitourinary 16 10857486 AT A CIITA 2.6e-08 421 210937 211358 Chronic inflammatory pelvic disease 1 614.32 1.0 genitourinary X 12986287 GTTAATAC G rs772650188 TMSB4X 2.6e-08 2345 212247 214592 Early or threatened labor; hemorrhage in early pregnancy 2 636 1.0 pregnancy complications 6 36904871 T C rs141738411 C6orf89 2.6e-08 547 401682 402229 Symptoms affecting skin 2 687 0.97444 dermatologic 1 229396383 C G rs184531937 ACTA1 2.6e-08 160 406081 406241 Other congenital anomalies of lower limb, including pelvic girdle 1 755.6 1.0669 congenital anomalies 5 178546737 A G rs1009977887 COL23A1 2.6e-08 98 193706 193804 Abnormal Papanicolaou smear of cervix and cervical HPV 3 792 0.97444 symptoms 10 62733475 A C rs552644930 AC024598.1 2.6e-08 223 380139 380362 Poisoning by primarily systemic agents 2 963 1.0534 injuries & poisonings 21 14201023 C A rs776998982 LIPI 2.7e-08 205 406672 406877 Other infectious and parasitic diseases 1 136 1.0601 infectious diseases 15 48109121 C T rs577066398 SLC24A5 2.7e-08 557 403455 404012 Chondrocalcinosis 2 274.21 0.97444 endocrine/metabolic 3 127253583 C T rs565561072 PRR20G 2.7e-08 136 401998 402134 Organic or persistent insomnia 1 327.41 1.0704 neurological 5 34067274 T G rs960233341 C1QTNF3-AMACR 2.7e-08 362 404472 404834 Lack of coordination 1 350.3 1.011 neurological 9 79537913 T C rs146256629 TLE4 2.7e-08 57 392385 392442 Nerve root lesions 1 353.2 1.0 neurological 3 9418394 T C rs370854428 SETD5 2.7e-08 69 386958 387027 Nonsenile Cataract 2 366.1 1.0224 sense organs 9 112068438 A G rs75359388 SUSD1 2.7e-08 516 390235 390751 Other disorders of cervical region 4 723 0.97444 musculoskeletal 3 45364144 A T rs189857107 LARS2 2.7e-08 530 399564 400094 Other specified osteoporosis 4 743.13 1.0 musculoskeletal X 147254087 C T rs782214758 CXorf51A 2.7e-08 370 403085 403455 Urticaria 2 947 1.011 injuries & poisonings 4 42609413 C G rs552517827 ATP8A1 2.8e-08 1197 404729 405926 Vitamin deficiency 1 261 1.0027 endocrine/metabolic X 118732416 T A rs1009714778 IL13RA1 2.8e-08 349 363985 364334 Psychogenic disorder 2 303.3 1.0166 mental disorders 3 164281310 G A rs182932933 SI 2.8e-08 988 379215 380203 Cardiac arrest 1 427.42 1.0 circulatory system 1 165022844 G A rs1382604784 PBX1 2.8e-08 467 401592 402059 Stomatitis and mucositis 1 528.1 0.97444 digestive 1 95259049 G A rs760311988 RWDD3 2.8e-08 78 393014 393092 Urinary complications NEC 2 597.2 1.0375 genitourinary 18 47715735 G A rs909270048 SMAD2 2.8e-08 717 405227 405944 Inflammatory disease of breast 1 613.1 0.97444 genitourinary 14 103600322 A G rs980452383 AL139300.1,COA8,KLC1 2.8e-08 125 400627 400752 Alopecia 2 704.1 1.0669 dermatologic 5 35952973 A T rs555716289 UGT3A1 2.8e-08 586 377182 377768 Rupture of synovium 4 727.5 0.97444 musculoskeletal 1 83263676 C T rs529658117 TTLL7 2.8e-08 2901 398900 401801 Other open wound of head and face 1 870.3 1.0 injuries & poisonings 7 4185521 C T rs879587225 SDK1 2.9e-08 147 401601 401748 Human immunodeficiency virus [HIV] disease 1 071 1.0704 infectious diseases 14 39990402 G A rs972127722 FBXO33 2.9e-08 69 406672 406741 Arthropod-borne diseases 1 133 1.0 infectious diseases 3 67322000 G C rs959134473 SUCLG2 2.9e-08 309 405057 405366 Cancer of tongue 1 145.2 1.0283 neoplasms X 86113292 TTTTA T DACH2 2.9e-08 436 406758 407194 Cancer of bone and connective tissue 2 170 1.0 neoplasms 2 202078368 G A rs571560525 KIAA2012 2.9e-08 92 403660 403752 Diabetes insipidus 1 253.3 1.0567 endocrine/metabolic 5 124846774 G C rs543184266 ZNF608 2.9e-08 374 405081 405455 Disorders of magnesium metabolism 1 275.3 1.011 endocrine/metabolic 2 239350724 A C rs1040076702 HDAC4 2.9e-08 901 404228 405129 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] 4 293.1 0.97444 mental disorders 7 29086165 G A rs947262327 CPVL 2.9e-08 248 393433 393681 Encephalopathy, not elsewhere classified 2 348.8 1.0469 neurological 2 209481056 C T rs747630114 MAP2 2.9e-08 71 399529 399600 Anomalies of pupillary function 1 379.4 1.0283 sense organs 1 47909151 G A rs79835221 TRABD2B 2.9e-08 834 397140 397974 Subarachnoid hemorrhage 1 430.1 0.97444 circulatory system 11 132609347 C A rs771896524 OPCML 2.9e-08 203 398705 398908 Aneurysm of other specified artery 1 442.8 1.0601 circulatory system 15 81179641 T G rs576745386 IL16 2.9e-08 72 396438 396510 Viral pneumonia 2 480.2 1.0138 respiratory 19 40232560 T C rs931909491 AKT2 2.9e-08 18639 383305 401944 Other symptoms/disorders or the urinary system 3 599 1.0313 genitourinary 9 7252587 A C rs185776107 KDM4C 2.9e-08 600 364268 364868 Osteomyelitis, periostitis, and other infections involving bone 3 710 0.97444 musculoskeletal 14 54669853 T C rs112147375 SAMD4A 2.9e-08 852 377183 378035 Bursitis 2 726.3 0.97444 musculoskeletal 13 105461343 G A rs566553219 DAOA 2.9e-08 587 406081 406668 Other congenital musculoskeletal anomalies 1 756 0.97444 congenital anomalies 16 6308967 C G rs7201177 RBFOX1 2.9e-08 243 403782 404025 Concussion 1 817 1.0469 injuries & poisonings 4 78979392 T C rs1353034028 PAQR3 2.9e-08 2084 389790 391874 Dislocation 3 830 1.0054 injuries & poisonings 10 22579014 G A rs764417286 PIP4K2A 2.9e-08 62 406579 406641 Toxic effect of carbon monoxide 1 986 1.0027 injuries & poisonings 8 135266928 C T rs764651556 KHDRBS3 3e-08 166 404551 404717 Aspergillosis 1 117.4 1.0739 infectious diseases 17 17317553 G A rs1024479045 NT5M 3e-08 681 387082 387763 Abnormal glucose 1 250.4 0.97444 endocrine/metabolic 12 124822084 G T rs148729131 SCARB1 3e-08 7297 399783 407080 Disorders of fluid, electrolyte, and acid-base balance 1 276 1.0027 endocrine/metabolic 13 103820898 G C rs1341444 SLC10A2 3e-08 2205 399528 401733 Disorders of lacrimal system 2 375 1.0082 sense organs 5 87772774 G A rs189904994 CCNH 3e-08 131 379216 379347 Other heart block 3 426.25 1.0704 circulatory system 16 3279195 C T rs545761580 ZNF263 3e-08 2137 397141 399278 Transient cerebral ischemia 2 433.31 1.0082 circulatory system 5 170322059 T C rs944641336 LCP2 3e-08 8893 397695 406588 Other diseases of respiratory system, NEC 1 519.8 1.0054 respiratory 18 2953792 G T rs629273 LPIN2 3e-08 3013 396444 399457 Diseases of hard tissues of teeth 1 521 1.0 digestive 20 540438 G A rs748085265 CSNK2A1 3e-08 330 396444 396774 Dentofacial anomalies, including malocclusion 1 524 1.0224 digestive 17 36661994 G A rs962265459 MRM1 3e-08 5294 383442 388736 Hemorrhage of gastrointestinal tract 1 578.9 1.0082 digestive 3 145078622 G A rs187787965 PLOD2 3e-08 2051 390237 392288 Other and unspecified disorders of back 1 724 1.011 musculoskeletal 16 52501843 C T rs16951213 TOX3 3e-08 1230 389420 390650 Malunion and nonunion of fracture 3 733.8 1.0 musculoskeletal 4 136712381 T A rs537831692 PCDH18 3e-08 3565 400905 404470 Symptoms and disorders of the joints 2 741 1.0 musculoskeletal 4 119977648 G A rs1228016849 MAD2L1 3e-08 76 406643 406719 Congenital cataract and lens anomalies 3 753.1 1.0 congenital anomalies 6 125153656 T C rs55736098 TPD52L1 3.1e-08 1012 406190 407202 Crushing or internal injury to organs 1 1008 1.0 injuries & poisonings 16 25681288 C G rs186432499 HS3ST4 3.1e-08 80 406672 406752 Spirochetal infection 2 130 1.0406 infectious diseases 18 84562 C T rs759506626 TUBB8B 3.1e-08 631 398900 399531 Vascular hamartomas and non-neoplastic nevi 2 217 0.97444 neoplasms 2 188117254 A G rs190084491 GULP1 3.1e-08 586 379215 379801 Atrioventricular block, complete 1 426.24 0.97444 circulatory system 4 112781243 C T rs779338351 ANK2 3.1e-08 142 386240 386382 Hemorrhage NOS 3 459.1 1.0704 circulatory system 2 154419691 G A rs901249786 GALNT13 3.1e-08 233 396443 396676 Temporomandibular joint disorder, unspecified 1 526.41 1.0469 digestive 10 3215594 C T rs142697685 PITRM1 3.1e-08 3875 401592 405467 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue 2 528 1.0054 digestive 7 44687091 ATTTTTTT A OGDH 3.1e-08 148 385684 385832 Toxic gastroenteritis and colitis 4 569.1 1.0635 digestive 20 6852347 C T rs116662646 BMP2 3.1e-08 6994 395835 402829 Renal failure 1 585 1.0027 genitourinary 15 87466598 T G rs923314126 NTRK3 3.1e-08 3529 403673 407202 Abnormal findings on examination of urine 2 598 1.0 genitourinary 2 28980489 T G rs539821568 TOGARAM2 3.1e-08 1913 383299 385212 Other abnormality of urination 1 599.9 1.0082 genitourinary 5 171090933 CA C rs1452727588 RANBP17 3.1e-08 282 401684 401966 Localized superficial swelling, mass, or lump 4 687.2 1.0313 dermatologic X 52335345 G A rs782105147 XAGE2 3.1e-08 1629 393234 394863 Other acquired deformities of limbs 1 736 1.0082 musculoskeletal 4 106571346 T C rs940099240 GIMD1 3.1e-08 613 400905 401518 Stiffness of joint 2 741.2 0.97444 musculoskeletal 2 40209048 G GA SLC8A1 3.1e-08 1519 386070 387589 Fracture of clavicle or scapula 2 803.3 1.011 injuries & poisonings 1 100898774 C T rs970785634 SLC30A7 3.1e-08 387 403085 403472 Dermatitis due to solar radiation 1 938 1.0027 injuries & poisonings 14 20656694 G C rs74892922 OR6S1 3.1e-08 549 403086 403635 Anaphylactic shock NOS 2 946 0.97444 injuries & poisonings 1 52382886 A AT ORC1 3.2e-08 241 404730 404971 Mineral deficiency NEC 1 262 1.0534 endocrine/metabolic 18 45870289 T G rs896847431 EPG5 3.2e-08 4089 399785 403874 Electrolyte imbalance 2 276.1 1.0 endocrine/metabolic 1 40882927 C T rs1296117501 CITED4 3.2e-08 291 399034 399325 Polycythemia, secondary 1 289.8 1.0344 hematopoietic 6 46206671 C T rs887349507 RCAN2 3.2e-08 935 379215 380150 Paroxysmal ventricular tachycardia 2 427.12 0.97444 circulatory system 6 824737 G A rs901348831 EXOC2 3.2e-08 64 400869 400933 Heart transplant/surgery 1 429.1 1.0166 circulatory system 11 37489939 A C rs185214090 IFTAP 3.2e-08 282 398705 398987 Acute vascular insufficiency of intestine 2 441.1 1.0344 circulatory system 2 112484516 C T rs546529284 TTL 3.2e-08 8112 376443 384555 Other specified gastritis 1 535.8 1.0166 digestive 3 192606469 G A rs755306092 FGF12 3.2e-08 1081 212248 213329 Hemorrhage in early pregnancy 1 636.3 0.97444 pregnancy complications 1 233530852 G A rs1185741198 KCNK1 3.2e-08 95 400908 401003 Pathological, developmental or recurrent dislocation 2 742.2 1.0567 musculoskeletal 5 169102905 T C rs1049562836 SLIT3 3.2e-08 51 406847 406898 Anomalies of respiratory system, congenital 1 748 0.97444 congenital anomalies 9 18525270 G T rs538023215 ADAMTSL1 3.2e-08 326 405003 405329 Upper gastrointestinal congenital anomalies 2 750.1 1.0224 congenital anomalies 5 148177319 A G rs1035794313 SPINK14 3.2e-08 511 380139 380650 Poisoning by anticonvulsants and anti-Parkinsonism drugs 2 966 0.97444 injuries & poisonings 6 145214447 A G rs6934107 EPM2A 3.3e-08 251 405058 405309 Cancer of oropharynx 1 149.1 1.0437 neoplasms 7 44080260 G A rs149902563 POLM 3.3e-08 131 387081 387212 Glycosuria or Acetonuria 1 250.5 1.0501 endocrine/metabolic 13 62237684 T G rs1416742177 AL592490.1 3.3e-08 169 399529 399698 Pain, swelling or discharge of eye 1 379.9 1.0635 sense organs 3 109559601 C T rs555429099 DPPA4 3.3e-08 233 379216 379449 Anomalous atrioventricular excitation 2 426.4 1.0501 circulatory system 7 152129456 G A rs1052878961 KMT2C 3.3e-08 921 398706 399627 Arterial embolism and thrombosis 2 444 0.97444 circulatory system 5 19828834 C G rs576263620 CDH18 3.3e-08 1122 388555 389677 Chronic tonsillitis and adenoiditis 1 474.2 1.0 respiratory 4 62306407 C T rs1043687772 ADGRL3 3.3e-08 153 367706 367859 Diverticulum of esophagus, acquired 1 530.6 1.0669 digestive 7 149767934 G A rs112624533 ZNF467 3.3e-08 485 385685 386170 Gastrointestinal complications 4 569.2 0.97444 digestive 6 12865735 C T rs114238222 PHACTR1 3.3e-08 99 395833 395932 Disorders resulting from impaired renal function 1 588 1.0635 genitourinary 2 201004447 C T rs58253853 FAM126B 3.3e-08 4310 215778 220088 Known or suspected fetal abnormality affecting management of mother 1 655 1.0082 pregnancy complications 18 73009445 A G rs28491374 NETO1 3.3e-08 779 406423 407202 Pruritus and related conditions 1 698 0.97444 dermatologic 13 63897862 G A rs187507978 AL445238.1 3.3e-08 590 397537 398127 Hyperhidrosis 2 705.8 0.97444 dermatologic 2 96543521 T C rs558755341 ARID5A 3.3e-08 150 400616 400766 Nonspecific findings on examination of blood 1 790 1.0669 symptoms 7 155732748 C T rs771431615 RBM33 3.4e-08 173 369609 369782 Benign neoplasm of kidney and other urinary organs 2 223 1.0669 neoplasms 4 162998615 C T rs769397982 NAF1 3.4e-08 1504 400601 402105 Aphasia/speech disturbance 1 292.1 1.0082 mental disorders 20 10419154 C T rs972296578 AL034430.1,MKKS 3.4e-08 90 363984 364074 Eating disorder 1 305.2 1.0501 mental disorders 6 135796034 C T rs541798367 PDE7B 3.4e-08 117 393432 393549 Spinocerebellar disease 3 334.1 1.0669 neurological 10 97622323 A C rs146783975 AL355315.1,MORN4 3.4e-08 190 404786 404976 Astigmatism 1 367.2 1.0601 sense organs 1 40052666 T G rs922602148 CAP1 3.4e-08 512 402827 403339 Tinnitus 1 389.4 0.97444 sense organs 16 53773852 A G rs17817288 FTO 3.4e-08 3100 385682 388782 Peritoneal adhesions (postoperative) (postinfection) 1 568.1 1.0027 digestive X 112961782 T C AMOT 3.4e-08 263 389420 389683 Osteitis deformans [Paget's disease of bone] 5 731.1 1.0254 musculoskeletal 18 23506721 GAT G rs572316177 NPC1,RMC1 3.4e-08 1640 405395 407035 Edema 1 782.3 1.0054 symptoms 16 82807014 C T rs140949681 CDH13 3.4e-08 55 406709 406764 Postoperative shock 4 958.1 1.0 injuries & poisonings 9 98974438 A T rs80070814 COL15A1 3.4e-08 869 380140 381009 Poisoning/allergy of sulfonamides 1 961.1 0.97444 injuries & poisonings 12 1670482 A G rs75819571 ADIPOR2 3.5e-08 396 389744 390140 Other disorders of thyroid 1 246 1.0027 endocrine/metabolic 22 23238481 C G rs554475517 BCR 3.5e-08 502 387082 387584 Type 2 diabetes with neurological manifestations 1 250.24 0.97444 endocrine/metabolic 6 131765840 G A rs528594353 ENPP3 3.5e-08 350 406625 406975 Develomental delays and disorders 1 315 1.0138 mental disorders 6 57380388 C T rs528967216 PRIM2 3.5e-08 369 328789 329158 Hypertensive heart disease 3 401.21 1.0082 circulatory system 3 120999025 G A rs146620887 STXBP5L 3.5e-08 705 406497 407202 Noninfectious disorders of lymphatic channels 2 450 0.95116 circulatory system 2 206759847 C T rs544397751 MDH1B 3.5e-08 97 367908 368005 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin 1 457 0.97444 circulatory system 7 136922866 G T rs1367119392 CHRM2 3.5e-08 84 401592 401676 Oral aphthae 1 528.12 1.0437 digestive 19 35101689 G A rs758618027 AC020907.6 3.5e-08 20872 383445 404317 Gastrointestinal hemorrhage 1 578 1.0224 digestive 19 5085934 G A rs949315533 KDM4B 3.5e-08 4533 395835 400368 Acute renal failure 2 585.1 1.0054 genitourinary 5 153405250 CA C rs1197341274 GRIA1 3.5e-08 302 207908 208210 Disorders secondary to childbirth, surgery, trauma 2 617 1.0313 genitourinary 8 42790867 C T rs967378907 CHRNA6 3.5e-08 1712 217129 218841 Malposition and malpresentation of fetus or obstruction 2 652 1.0 pregnancy complications 11 49338131 A G rs1016487890 FOLH1 3.5e-08 361 395973 396334 Pyogenic granuloma 2 686.4 1.0082 dermatologic 12 117135504 C T rs139776059 FBXO21 3.5e-08 351 390235 390586 Other allied disorders of spine 4 721.8 1.0166 musculoskeletal 1 244973207 T C rs985762458 EFCAB2 3.5e-08 2830 390235 393065 Degeneration of intervertebral disc 1 722.6 1.0027 musculoskeletal 10 79310608 G T rs1044297408 ZMIZ1 3.5e-08 207 389418 389625 Juvenile osteochondrosis 1 732.1 1.0601 musculoskeletal 3 31318832 A T rs1038702895 STT3B 3.5e-08 487 393242 393729 Contracture of joint 1 739 0.97444 musculoskeletal 7 137941542 T A rs273990 CREB3L2 3.5e-08 11214 395988 407202 Back pain 2 760 1.0344 symptoms 3 54221295 C T rs780490662 CACNA2D3 3.5e-08 64 380139 380203 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system 1 975 1.011 injuries & poisonings 19 43286293 T G rs572170979 PSG9 3.6e-08 773 405448 406221 Benign neoplasm of brain, cranial nerves, meninges 1 225.1 0.97444 neoplasms 14 34127318 G A rs145643129 EGLN3 3.6e-08 218 389743 389961 Chronic thyroiditis 2 245.2 1.0534 endocrine/metabolic 14 28685264 C T rs558823069 FOXG1 3.6e-08 191 406469 406660 Paraproteinemia 3 270.32 1.0601 endocrine/metabolic 2 129588114 C T rs746096585 RAB6C 3.6e-08 182 395155 395337 Peripheral retinal degenerations 3 362.6 1.0669 sense organs 3 38565977 A G rs62241190 SCN5A 3.6e-08 984 379218 380202 First degree AV block 2 426.21 1.0 circulatory system 1 20528985 T C rs1380162823 MUL1 3.6e-08 9411 397696 407107 Other diseases of respiratory system, not elsewhere classified 1 519 1.0082 respiratory 20 54629290 C T rs374186877 DOK5 3.6e-08 1679 367706 369385 Esophageal bleeding (varices/hemorrhage) 3 530.2 1.011 digestive 5 169765698 AAG A DOCK2 3.6e-08 927 385683 386610 Peritonitis and retroperitoneal infections 1 567 0.97444 digestive X 142058928 G A rs1410407903 MAGEC2 3.6e-08 12461 378357 390818 Urinary tract infection 2 591 1.011 genitourinary 4 13635640 A C rs1325868937 BOD1L1 3.6e-08 213 219860 220073 Excessive vomiting in pregnancy 1 643 1.0254 pregnancy complications 1 190808811 T C rs923712823 BRINP3 3.6e-08 148 364268 364416 Arthropathy associated with other disorders classified elsewhere 1 713 1.0635 musculoskeletal 8 107061666 C G rs150991783 ANGPT1 3.6e-08 1775 389420 391195 Other disorders of bone and cartilage 1 733 1.0082 musculoskeletal 17 74318321 G T rs1403902940 DNAI2 3.6e-08 180 403085 403265 Allergic reaction to food 1 930 1.0669 injuries & poisonings 3 66558543 G A rs1207664780 LRIG1 3.7e-08 658 391484 392142 Pancreatic cancer 2 157 0.97444 neoplasms 1 108215143 A C rs574477373 NBPF4 3.7e-08 1387 396050 397437 Retinal detachment with retinal defect 1 361.1 1.0027 sense organs 19 54456744 C T rs770764339 LENG8 3.7e-08 90 396051 396141 Corneal opacity 1 364.1 1.0469 sense organs 15 93918886 G A rs546695948 MCTP2 3.7e-08 75 400268 400343 Pulmonary embolism and infarction, acute 2 415.11 1.0283 circulatory system 2 9601899 C T rs552132358 YWHAQ 3.7e-08 169 398705 398874 Aneurysm of artery of lower extremity 2 442.3 1.0669 circulatory system 1 120004182 C T rs375724393 NOTCH2 3.7e-08 912 398129 399041 Other dyspnea 2 512.9 1.0 respiratory 2 154419691 G A rs901249786 GALNT13 3.7e-08 240 396443 396683 Temporomandibular joint disorders 1 526.4 1.0437 digestive 16 88696195 T C rs767214362 RNF166 3.7e-08 364 401593 401957 Sialoadenitis 1 527.2 1.0082 digestive 13 50587029 C T rs1341637 DLEU7 3.7e-08 1565 169005 170570 Prostatitis 1 601.1 1.0138 genitourinary 5 166490239 G A rs1278777829 TENM2 3.7e-08 796 210673 211469 Symptoms involving female genital tract 1 624 0.97444 genitourinary 6 10691103 C G rs1251739967 C6orf52 3.7e-08 966 400628 401594 Ingrowing nail 3 703.1 1.0 dermatologic X 48775511 G A rs782634830 GLOD5 3.7e-08 193 364268 364461 Chronic osteomyelitis 1 710.12 1.0669 musculoskeletal 7 159261692 T C rs575638591 VIPR2 3.8e-08 299 406903 407202 Other signs and symptoms involving emotional state 2 1004 1.0344 injuries & poisonings 2 37366911 T C rs142235232 QPCT 3.8e-08 6866 363982 370848 Anxiety disorders 3 300 1.0166 mental disorders 7 101840005 G A rs570481667 CUX1 3.8e-08 2857 397071 399928 Migraine 1 340 1.0 neurological 6 163683885 G A rs979693839 QKI 3.8e-08 116 395154 395270 Retinal hemorrhage/ischemia 1 362.8 1.0406 sense organs 19 15520719 C T rs537577687 CYP4F22 3.8e-08 2402 404788 407190 Disorders of refraction and accommodation; blindness and low vision 3 367 1.0027 sense organs 10 96700254 G A rs945722992 PIK3AP1 3.8e-08 752 406415 407167 Other diseases of lung 1 510 0.97444 respiratory 1 231041331 T C rs1361527647 FAM89A 3.8e-08 328 396444 396772 Cysts of the jaws 1 526.1 1.0195 digestive 18 51328658 C T rs748252653 MEX3C 3.8e-08 671 333377 334048 Ulceration of intestine 1 556.1 0.97444 digestive 3 132155992 T C rs569520094 CPNE4 3.8e-08 300 213273 213573 Fibrosclerosis of breast 1 610.3 1.0344 genitourinary 12 49203816 G A rs943848822 TUBA1C 3.8e-08 130 399659 399789 Cutaneous lupus erythematosus 2 695.41 1.0635 dermatologic 8 106943173 C T rs58384262 ABRA 3.8e-08 57 389419 389476 Osteochondritis dissecans 2 732.7 1.0 musculoskeletal 8 39300800 T G rs1003750271 ADAM32 3.8e-08 3260 393233 396493 Complication due to other implant and internal device 2 859 1.0 injuries & poisonings 6 411064 A G rs872071 IRF4 3.9e-08 575 402712 403287 Lymphoid leukemia 1 204.1 0.97444 neoplasms 1 10682956 A G rs560754388 CASZ1 3.9e-08 750 388396 389146 Pernicious anemia 2 281.11 0.97444 hematopoietic 9 7290788 G T rs62529859 KDM4C 3.9e-08 776 393434 394210 Other conditions of brain 2 348 0.97444 neurological 11 41663310 G A rs1004742962 LRRC4C 3.9e-08 360 399529 399889 Disorders of optic nerve and visual pathways 2 377 1.011 sense organs 2 190545690 AT A rs776213558 NEMP2 3.9e-08 950 379216 380166 Arrhythmia (cardiac) NOS 2 427.5 0.97444 circulatory system 22 35397431 G A rs770958982 MCM5 3.9e-08 693 401593 402286 Diseases of the salivary glands 2 527 0.97444 digestive 14 102226813 C T rs1015374490 MOK 3.9e-08 420 383443 383863 Splenomegaly 2 579.2 1.0 digestive 3 90109822 G A rs1032859862 EPHA3 3.9e-08 234 380137 380371 Personal history of allergy to medicinal agents 1 977 1.0501 injuries & poisonings 16 76475382 G C rs916112612 AC106741.1,CNTNAP4 4e-08 979 405058 406037 Benign neoplasm of lip, oral cavity, and pharynx 1 210 1.0 neoplasms 21 28361964 T C rs1374088953 N6AMT1 4e-08 160 185582 185742 Testicular dysfunction 1 257 1.0669 endocrine/metabolic 5 4077187 G T rs954618699 IRX1 4e-08 753 404730 405483 Vitamin B-complex deficiencies 1 261.2 0.97444 endocrine/metabolic 4 17722361 G A rs780656545 FAM184B 4e-08 1733 401103 402836 Vertiginous syndromes and other disorders of vestibular system 1 386 1.011 sense organs 12 126215326 CA C rs11312097 TMEM132B 4e-08 1056 400661 401717 Disease of tricuspid valve 1 394.7 1.0 circulatory system 18 69529096 T C rs879573626 DOK6 4e-08 10395 396439 406834 Pneumonia 1 480 1.011 respiratory 2 55571768 G A rs139606600 PPP4R3B 4e-08 277 406591 406868 Hyperventilation 1 513.4 1.0313 respiratory 20 58264011 T G rs77751390 ANKRD60 4e-08 3359 333381 336740 Other intestinal obstruction 3 560.4 1.0027 digestive 4 187073357 T C rs775041705 FAT1 4e-08 521 403783 404304 Intracranial hemorrhage (injury) 2 818 0.97444 injuries & poisonings 4 78816027 A T rs1020291059 BMP2K 4.1e-08 399 391484 391883 Cancer of liver and intrahepatic bile duct 1 155 1.0054 neoplasms X 31596348 T C rs994587790 DMD 4.1e-08 112 403454 403566 Gouty arthropathy 1 274.11 1.0601 endocrine/metabolic 18 26524161 C A rs991885440 KCTD1 4.1e-08 149 363984 364133 Generalized anxiety disorder 1 300.11 1.0704 mental disorders 19 23366817 A G rs771122983 ZNF91 4.1e-08 893 393434 394327 Extrapyramidal disease and abnormal movement disorders 1 333 0.97444 neurological 20 19473382 G C rs6106083 SLC24A3 4.1e-08 885 404474 405359 Abnormal involuntary movements 1 350.1 1.0 neurological 16 78579731 G C rs146473943 WWOX 4.1e-08 251 404788 405039 Hypermetropia 2 367.8 1.0437 sense organs 6 24013098 G A rs528304301 NRSN1 4.1e-08 1255 395834 397089 Cyst of kidney, acquired 2 586.2 1.0 genitourinary X 112961782 T C AMOT 4.1e-08 278 389420 389698 Osteitis deformans and osteopathies associated with other disorders classified elsewhere 4 731 1.0224 musculoskeletal 4 106878323 A G rs1459692271 DKK2 4.2e-08 861 398254 399115 Viral Enteritis 1 008.6 0.97444 infectious diseases 20 45462303 T C rs571390402 PIGT 4.2e-08 64 401601 401665 Varicella infection 1 079.1 1.0166 infectious diseases X 7996727 C CT rs1251922459 PNPLA4 4.2e-08 160 180551 180711 Benign neoplasm of male genital organs 1 222 1.0739 neoplasms 11 3442631 A G rs562153547 ZNF195 4.2e-08 715 400868 401583 Ill-defined descriptions and complications of heart disease 1 429 0.97444 circulatory system 1 109833280 TAAAG T rs531551162 GSTM5 4.2e-08 368 376447 376815 Atrophic gastritis 1 535.2 1.011 digestive 8 145063722 C T rs1053031123 C8orf33 4.2e-08 2082 169006 171088 Inflammatory diseases of prostate 1 601 1.011 genitourinary 4 18935507 G A rs572270344 LCORL 4.2e-08 1187 210672 211859 Dyspareunia 1 625.1 1.0 genitourinary 16 67026250 C T rs1051410179 CBFB 4.2e-08 2735 377184 379919 Synovitis and tenosynovitis 2 727.1 1.0 musculoskeletal 15 62953042 T A rs1254857516 TPM1 4.2e-08 189 393241 393430 Flat foot 1 735.1 1.0635 musculoskeletal 4 174293687 G T rs140425685 CEP44 4.2e-08 5080 393238 398318 Acquired toe deformities 2 735.2 1.0166 musculoskeletal 13 107257149 TC T rs768698509 FAM155A 4.2e-08 1511 393242 394753 Acquired spondylolisthesis 1 738.4 1.0138 musculoskeletal 11 85033739 A G rs907428996 DLG2 4.2e-08 1791 405411 407202 Cervicalgia 1 761 1.0082 symptoms 11 34631415 G A rs79488065 EHF 4.2e-08 108 380139 380247 Poisoning by agents primarily affecting the gastrointestinal system 2 973 1.0635 injuries & poisonings 1 110662756 C T rs781277668 KCNA3 4.3e-08 427 401601 402028 Hepatitis NOS 1 070.9 1.0 infectious diseases 5 115193007 G T rs751984394 PGGT1B 4.3e-08 8509 398693 407202 Injury, NOS 1 1009 1.011 injuries & poisonings 8 125002767 A C rs554120056 SQLE 4.3e-08 568 391483 392051 Cancer of stomach 1 151 0.97444 neoplasms 11 124181515 T C rs563796996 OR10D3 4.3e-08 574 401102 401676 Meniere's disease 2 386.1 0.97444 sense organs 7 71336171 G A rs765392822 GALNT17 4.3e-08 127 403885 404012 Myocarditis 2 420.1 1.0739 circulatory system 7 11933465 T C rs1048540528 THSD7A 4.3e-08 193 396438 396631 Acute bronchitis and bronchiolitis 2 483 1.0601 respiratory 5 162131085 T C rs770842943 GABRG2 4.3e-08 2087 367709 369796 Heartburn 1 530.9 1.011 digestive X 121317778 G A rs1310206877 GLUD2 4.3e-08 257 376447 376704 Dyspepsia and other specified disorders of function of stomach 1 536.8 0.95116 digestive 8 115634536 T C rs77193180 TRPS1 4.3e-08 13161 383446 396607 Hemorrhage of rectum and anus 1 578.8 1.0166 digestive 15 82382149 A G rs1011617602 GOLGA6L10 4.3e-08 166 383297 383463 Urinary obstruction 1 599.1 1.0669 genitourinary 7 137653103 GGTGT G rs916760284 DGKI 4.3e-08 2154 386070 388224 Fracture of tibia and fibula 1 800.3 1.0054 injuries & poisonings 7 66465072 C T rs187195227 TPST1 4.4e-08 59 405449 405508 Benign neoplasm of spinal cord, meninges 2 225.2 1.0 neoplasms 13 58916010 A T rs74679390 DIAPH3 4.4e-08 282 363985 364267 Sexual and gender identity disorders 2 302 1.0283 mental disorders 3 152898506 G A rs1036332066 P2RY1 4.4e-08 276 393432 393708 Partial epilepsy 1 345.12 1.0375 neurological 12 73368837 TTAG T rs770831715 TRHDE 4.4e-08 3023 396445 399468 Dental caries 1 521.1 1.0 digestive 4 60690104 C T rs889839411 ADGRL3 4.4e-08 1544 383442 384986 Other symptoms involving abdomen and pelvis 2 579 1.0082 digestive 7 70652982 T C rs946103906 AUTS2 4.4e-08 2536 210933 213469 Pelvic peritoneal adhesions, female (postoperative) (postinfection) 1 614.1 1.0 genitourinary 2 24432677 C T rs533647283 NCOA1 4.4e-08 511 207909 208420 Prolapse of vaginal vault after hysterectomy 1 618.5 0.97444 genitourinary 7 1343744 C T rs575690799 MICALL2 4.5e-08 410 401602 402012 Herpes zoster 1 053 1.0 infectious diseases 15 27491221 C T rs558746442 GABRG3 4.5e-08 2264 368850 371114 Secondary malignancy of respiratory organs 1 198.2 1.0027 neoplasms 22 23042290 T C rs186156583 RSPH14 4.5e-08 144 402713 402857 Myeloid leukemia, chronic 1 204.22 1.0739 neoplasms 13 78573265 G T rs17759358 POU4F1 4.5e-08 53 406624 406677 Autism 1 313.3 0.97444 mental disorders 6 152595558 T C rs73005839 SYNE1 4.5e-08 141 397602 397743 Corneal ulcer 1 370.1 1.0704 sense organs 15 90634070 A G rs187909076 CRTC3 4.5e-08 614 398705 399319 Vascular insufficiency of intestine 1 441 0.97444 circulatory system 7 152129456 G A rs1052878961 KMT2C 4.5e-08 553 398706 399259 Arterial embolism and thrombosis of lower extremity artery 2 444.1 0.97444 circulatory system 8 69096232 C T rs986306302 C8orf34 4.5e-08 77 405229 405306 Mastodynia 1 613.5 1.0406 genitourinary 2 94922127 A G rs187657450 TEKT4 4.5e-08 828 210938 211766 Pelvic inflammatory disease (PID) 1 614.3 0.97444 genitourinary 3 182585848 G A rs75042980 ATP11B 4.5e-08 590 403791 404381 Chronic fatigue syndrome 2 798.1 0.97444 symptoms 4 91007924 T G rs781658355 CCSER1 4.5e-08 220 398898 399118 Open wound of nose and sinus 1 870.4 1.0635 injuries & poisonings 16 3302495 C T rs147068183 TIGD7 4.6e-08 1198 406004 407202 Foreign body injury 1 1001 1.0 injuries & poisonings 6 3202263 C T rs12201247 TUBB2B 4.6e-08 292 363984 364276 Adjustment reaction 1 304 1.0313 mental disorders 8 86095677 C T rs116403010 ATP6V0D2 4.6e-08 8944 377722 386666 Alcoholism 2 317.1 1.0283 mental disorders 10 50976239 C T rs1295794958 PRKG1 4.6e-08 69 396051 396120 Chorioretinal scars 1 363.3 1.0195 sense organs 6 85476161 T C rs17220898 NT5E 4.6e-08 1078 388553 389631 Voice disturbance 1 473.4 1.0 respiratory 4 178558460 C G rs11726255 AGA 4.6e-08 2866 398128 400994 Cough 2 512.8 1.0 respiratory 10 20304020 G C rs542486958 PLXDC2 4.6e-08 665 396444 397109 Acute periodontitis 1 523.31 0.97444 digestive 6 17664673 A C rs899172255 NUP153 4.6e-08 2596 210932 213528 Inflammatory disease of cervix, vagina, and vulva 1 614.5 1.0 genitourinary 12 61456011 G A rs78792762 TAFA2 4.7e-08 211 371432 371643 Unspecified disorder of lipoid metabolism 1 272.9 1.0567 endocrine/metabolic 3 72733261 C T rs1430489647 SHQ1 4.7e-08 1551 404526 406077 Thrombocytopenia 2 287.3 1.0054 hematopoietic 10 10313829 A G rs571172255 CELF2 4.7e-08 285 400601 400886 Specific nonpsychotic mental disorders due to brain damage 1 291.4 1.0254 mental disorders 14 48387607 A G rs928842735 MDGA2 4.7e-08 133 393432 393565 Cerebral cysts 1 348.4 1.0669 neurological 8 77043913 G A rs1392080653 PEX2 4.7e-08 400 379216 379616 Sinoatrial node dysfunction (Bradycardia) 1 427.8 1.0027 circulatory system 1 154536903 C T rs924206371 TDRD10 4.7e-08 4080 388550 392630 Other upper respiratory disease 1 479 1.0027 respiratory 13 113548469 C T rs375060916 TMCO3 4.7e-08 4673 402142 406815 Other hypertrophic and atrophic conditions of skin 1 701 1.0 dermatologic 13 85738430 G A rs776199675 SLITRK6 4.8e-08 129 404523 404652 Spontaneous ecchymoses 1 287.1 1.0635 hematopoietic 9 90657625 T C rs114331012 DIRAS2 4.8e-08 387 395581 395968 Dependence on respirator [Ventilator] or supplemental oxygen 1 509.8 1.011 respiratory 7 120525991 C A rs914660306 KCND2 4.8e-08 261 219609 219870 Other complications of the puerperium NEC 3 674 1.0166 pregnancy complications 9 69842573 A T rs149925809 C9orf135 4.8e-08 3113 401346 404459 Effects radiation NOS 1 990 1.0 injuries & poisonings 20 4033784 T C rs950919485 RNF24 4.9e-08 141 404551 404692 Althete's foot 1 110.12 1.0739 infectious diseases X 91308251 AAAT A PABPC5 4.9e-08 2046 399285 401331 Renal colic 1 594.8 1.011 genitourinary 6 131723175 A C rs549945735 ENPP3 4.9e-08 1108 218980 220088 Hypertension complicating pregnancy, childbirth, and the puerperium 1 642 0.97444 pregnancy complications 20 6927034 A T rs555684799 BMP2 5e-08 211 401600 401811 Herpes simplex 1 054 1.0601 infectious diseases 7 100002188 C T rs547529299 ZKSCAN1 5e-08 1423 399786 401209 Hypopotassemia 1 276.14 1.0082 endocrine/metabolic 8 28384798 C T rs186478288 FBXO16,ZNF395 5e-08 132 400599 400731 Transient mental disorders due to conditions classified elsewhere 1 291.1 1.0635 mental disorders 3 72851866 G A rs574748028 SHQ1 5e-08 336 396052 396388 Disorders of the globe 1 360 1.0166 sense organs 9 128344304 C T rs185413009 SLC27A4 5e-08 681 401594 402275 Diseases of lips 1 528.5 0.97444 digestive 4 2352470 C T rs552620876 ZFYVE28 5.1e-08 56 402714 402770 Lymphoid leukemia, acute 0 204.11 1.0 neoplasms 8 86375501 A G rs117864771 WWP1 5.1e-08 270 388396 388666 Acute posthemorrhagic anemia 0 285.1 1.0375 hematopoietic 3 173485877 G C rs185957555 NLGN1 5.1e-08 306 400600 400906 Hallucinations 0 292.6 1.0254 mental disorders 4 183461996 A T rs1190955780 CDKN2AIP 5.1e-08 60 377720 377780 Polyneuropathy due to drugs 0 316.1 1.0 mental disorders 4 147299200 T C rs755035987 EDNRA 5.1e-08 1750 379217 380967 Left bundle branch block 0 426.32 1.0054 circulatory system 12 48606654 A G rs756591375 LALBA 5.1e-08 3223 379215 382438 Other specified cardiac dysrhythmias 0 427.3 1.0027 circulatory system 20 56257217 A C rs1238649542 MC3R 5.1e-08 1349 210805 212154 Noninflammatory disorders of vulva and perineum 0 619.5 1.0054 genitourinary 18 50238751 G C rs35839946 CFAP53 5.1e-08 190 380139 380329 Poisoning by drugs primarily affecting the autonomic nervous system 0 971 1.0601 injuries & poisonings 10 113800203 G A rs577737640 PLEKHS1 5.2e-08 493 392085 392578 Gram positive septicemia 0 038.2 0.97444 infectious diseases 5 22144734 G A rs897955655 CDH12 5.2e-08 131 406757 406888 Bone cancer 0 170.1 1.0704 neoplasms 15 59453974 C A rs560329176 FAM81A 5.2e-08 181 393366 393547 Neoplasm of uncertain behavior of skin 0 173 1.0635 neoplasms 21 26788700 G A rs778801992 ADAMTS1 5.2e-08 2160 368845 371005 Secondary malignancy of bone 0 198.6 1.0054 neoplasms 8 22159073 G A rs759530185 SFTPC 5.2e-08 249 373884 374133 Asthma with exacerbation 0 495.2 1.0469 respiratory 11 40647674 G T rs1187526567 LRRC4C 5.2e-08 107 390234 390341 Torticollis 0 723.1 1.0567 musculoskeletal X 141575815 T G rs1247404579 SPANXA1 5.2e-08 170 386068 386238 Fracture of unspecified part of femur 0 800.2 1.0704 injuries & poisonings 11 83751128 A T rs116957015 DLG2 5.3e-08 695 400598 401293 Memory loss 0 292.3 0.97444 mental disorders 6 20787348 T G rs759655427 CDKAL1 5.3e-08 925 213273 214198 Cystic mastopathy 0 610.1 0.97444 genitourinary 9 33871624 G A rs757702643 UBE2R2 5.3e-08 149 406232 406381 Chromosomal anomalies and genetic disorders 0 758 1.0635 congenital anomalies 1 114353040 C G rs181362281 TRIM33 5.3e-08 370 380139 380509 Poisoning by hormones and synthetic substitutes 0 962 1.011 injuries & poisonings 13 111492410 C T rs147210953 TEX29 5.4e-08 698 388394 389092 Anemia of chronic disease 0 285.2 0.97444 hematopoietic 10 116702172 G A rs756964696 HSPA12A 5.4e-08 51 404523 404574 Allergic purpura 0 287.2 0.97444 hematopoietic 2 202750996 G T rs912290767 FAM117B 5.4e-08 86 399529 399615 Disorders of the orbit 0 376 1.0313 sense organs 7 138175730 T G rs780734629 AKR1D1 5.4e-08 1824 374658 376482 Other forms of chronic heart disease 0 414 1.011 circulatory system 5 29806753 GTAGCTAAGTGTAGCAT G rs1579643980 CDH6 5.4e-08 495 395832 396327 Renal dialysis 0 585.31 0.97444 genitourinary 15 93470347 A G rs778304854 RGMA 5.4e-08 466 400951 401417 Unspecified erythematous condition 0 695.9 0.97444 dermatologic 11 129293893 G T rs756481248 ARHGAP32 5.4e-08 14785 377192 391977 Peripheral enthesopathies and allied syndromes 0 726 1.0344 musculoskeletal 5 179133535 G T rs755489467 ADAMTS2 5.5e-08 254 401602 401856 Viral hepatitis C 0 070.3 1.0469 infectious diseases 17 49203742 A G rs1051391157 GNGT2 5.5e-08 1650 404525 406175 Purpura and other hemorrhagic conditions 0 287 1.0082 hematopoietic 6 31798087 T A rs1144710 LSM2 5.5e-08 298 333378 333676 Intestinal malabsorption (non-celiac) 0 557 1.0344 digestive 10 38635914 G A rs193078783 AL117339.4 5.5e-08 350 210937 211287 Pelvic inflammatory disease, NOS 0 614.33 1.0138 genitourinary X 19275065 G T rs1316879846 PDHA1 5.5e-08 454 402139 402593 Abnormal granulation tissue 0 701.5 0.97444 dermatologic 4 5872397 A G rs115912484 CRMP1 5.5e-08 225 405001 405226 Congenital anomalies of intestine 0 750.21 1.0501 congenital anomalies 8 53956644 G A rs760152895 RGS20 5.5e-08 101 380139 380240 Poisoning by water, mineral, and uric acid metabolism drugs 0 974 1.0437 injuries & poisonings 5 168403605 C T rs1049597690 WWC1 5.6e-08 3130 392082 395212 Staphylococcus infections 0 041.1 1.0 infectious diseases 6 126895926 C T rs148849365 RSPO3 5.6e-08 680 403659 404339 Disorders of the pituitary gland and its hypothalamic control 0 253 0.97444 endocrine/metabolic 2 120519568 A G rs142011445 INHBB 5.6e-08 415 388395 388810 Anemia in neoplastic disease 0 285.22 1.0 hematopoietic 4 159720932 A G rs188688635 RAPGEF2 5.6e-08 463 392385 392848 Trigeminal nerve disorders [CN5] 0 352.1 1.0 neurological 4 25692844 A C rs754747728 SLC34A2 5.6e-08 533 403915 404448 Amblyopia 0 368.1 0.97444 sense organs 13 33950562 G C rs1359718781 RFC3 5.6e-08 910 399531 400441 Strabismus (not specified as paralytic) 0 378.1 1.0 sense organs 4 93765501 G A rs148365102 GRID2 5.6e-08 1191 379215 380406 Cardiac arrest and ventricular fibrillation 0 427.4 1.0 circulatory system 11 107008105 G A rs138809461 GUCY1A2 5.7e-08 115 387422 387537 Neoplasm of uncertain behavior of breast 0 174.3 1.0669 neoplasms 6 4324302 CAA C rs1039805981 ECI2 5.7e-08 88 406624 406712 Speech and language disorder 0 315.2 1.0469 mental disorders 10 80012308 G A rs1340696950 SFTPD 5.7e-08 3516 364266 367782 Unspecified polyarthropathy or polyarthritis 0 716.1 1.0082 musculoskeletal 3 182089816 G T rs950043598 SOX2 5.7e-08 839 405003 405842 Congenital anomalies of urinary system 0 751.2 1.0 congenital anomalies 5 133400067 C T rs770129918 FSTL4 5.8e-08 66 403024 403090 Malignant neoplasm of renal pelvis 0 189.12 1.0313 neoplasms 4 2080674 G A rs1045698060 HAUS3,POLN 5.8e-08 103 403659 403762 Cushing's syndrome 0 255.11 1.0567 endocrine/metabolic 19 46978508 G A rs569278621 ARHGAP35 5.8e-08 337 406470 406807 Proteinuria 0 269 1.0195 endocrine/metabolic 13 57033112 T C rs1001114451 PRR20A 5.8e-08 74 217127 217201 Other and unspecified complications of birth; puerperium affecting management of mother 0 654 1.0344 pregnancy complications 4 43707623 A T rs192044839 KCTD8 5.8e-08 164 219608 219772 Venous/cerebrovascular complications embolism in pregnancy and the puerperium 0 671 1.0534 pregnancy complications 13 61481054 C T rs7994898 AL592490.1 5.9e-08 848 368850 369698 Secondary malignancy of brain/spine 0 198.5 0.97444 neoplasms 20 7787157 G A rs745586962 HAO1 5.9e-08 1680 397135 398815 Cerebral artery occlusion, with cerebral infarction 0 433.21 1.0054 circulatory system 4 149798125 A G rs1054835782 IQCM 5.9e-08 2066 395582 397648 Respiratory failure 0 509.1 1.0082 respiratory 2 20508195 GA G rs1379267153 HS1BP3 5.9e-08 120 401593 401713 Other specified diseases of the salivary glands 0 527.8 1.0601 digestive 11 9627176 C T rs1039154404 WEE1 5.9e-08 1493 398277 399770 Other disorders of liver 0 573 1.0082 digestive 2 162100841 T A rs57355997 DPP4 5.9e-08 286 169005 169291 Balanoposthitis 0 601.4 1.0195 genitourinary 2 4164096 C T rs1021329126 DCDC2C 5.9e-08 56 400113 400169 Abnormal mammogram 0 611.1 1.0082 genitourinary 3 170239998 A G rs749265102 PRKCI 5.9e-08 1780 189133 190913 Dysmenorrhea 0 626.2 1.0082 genitourinary 1 7381617 G A rs538058010 CAMTA1 5.9e-08 121 389419 389540 Chondromalacia 0 733.9 1.0739 musculoskeletal 3 177087513 G C rs542548825 TBL1XR1 5.9e-08 5261 393232 398493 Hemorrhage or hematoma complicating a procedure 0 850 1.0027 injuries & poisonings 5 15535270 T C rs145747974 FBXL7 6e-08 248 406707 406955 Other immunological findings 0 279.7 1.0344 endocrine/metabolic 22 24574586 G A rs1048021188 AP000356.5,SNRPD3 6e-08 4442 401996 406438 Sleep apnea 0 327.3 1.0138 neurological 10 39278720 T A rs1261651846 AL117339.4 6e-08 79 395582 395661 Extrinsic allergic alveolitis 0 500.1 1.0375 respiratory 13 68238853 A C rs1013908482 PCDH9 6e-08 159 189130 189289 Premenstrual tension syndromes 0 626.4 1.0635 genitourinary 3 13098511 G A rs1025805686 IQSEC1 6e-08 3713 390237 393950 Spinal stenosis 0 720 1.011 musculoskeletal 8 58357023 T C rs556455868 UBXN2B 6e-08 234 404388 404622 Valvular heart disease/ heart chambers 0 747.12 1.0534 congenital anomalies 21 40847373 C T rs908781304 DSCAM 6.1e-08 4475 400603 405078 Postoperative infection 0 080 1.011 infectious diseases 4 173389281 T A rs778920963 SCRG1 6.1e-08 461 402714 403175 Myeloid leukemia 0 204.2 1.0 neoplasms 11 45047365 AGACCAACCG A rs56003391 PRDM11 6.1e-08 145 393432 393577 Infantile cerebral palsy 0 343 1.0739 neurological 1 221878992 TA T rs1471509682 DUSP10 6.1e-08 122 401593 401715 Cysts of oral soft tissues 0 528.4 1.0601 digestive 9 19894628 G A rs186642108 SLC24A2 6.1e-08 630 406572 407202 Myalgia and myositis unspecified 0 770 0.97444 symptoms 6 168605648 C T rs116519338 SMOC2 6.1e-08 156 407046 407202 Shock 0 797 1.0739 symptoms 3 188565722 A G rs758586603 LPP 6.2e-08 2476 400609 403085 Infection/inflammation of internal prosthetic device; implant; and graft 0 081 1.0 infectious diseases 1 35270848 G A rs759581794 ZMYM4 6.2e-08 97 400662 400759 Nonrheumatic pulmonary valve disorders 0 395.4 1.0437 circulatory system 2 45681950 C T rs72799074 PRKCE 6.2e-08 152 219860 220012 Hyperemesis gravidarum 0 643.1 1.0283 pregnancy complications 5 55355046 A G rs537632840 MTREX 6.3e-08 860 405668 406528 Benign neoplasm of other endocrine glands and related structures 0 227 0.97444 neoplasms 22 24428223 CA C rs769572658 ADORA2A,SPECC1L-ADORA2A 6.3e-08 90 399654 399744 Abnormality of red blood cells 0 289.9 1.0437 hematopoietic 3 193687375 C T rs117576206 OPA1 6.3e-08 610 406590 407200 Respiratory abnormalities 0 513 0.97444 respiratory 17 81304396 G A rs138621445 SLC38A10 6.3e-08 303 403669 403972 Other nonspecific findings on examination of urine 0 598.9 1.0283 genitourinary 2 60395497 G A rs942154397 BCL11A 6.4e-08 186 405668 405854 Benign neoplasm of adrenal gland 0 227.1 1.0669 neoplasms 4 59782487 C CA rs1396633576 ADGRL3 6.4e-08 451 399784 400235 Fluid overload 0 276.6 1.0 endocrine/metabolic 9 69255510 G A rs758113687 TJP2 6.4e-08 53 363984 364037 Dysthymic disorder 0 300.4 1.0 mental disorders 11 106402223 G A rs141306653 GUCY1A2 6.4e-08 766 406436 407202 Pain 0 338 0.97444 neurological 4 182788791 A G rs115087518 TENM3 6.4e-08 896 399530 400426 Epiphora 0 375.2 0.97444 sense organs 6 50373493 C A rs1165062862 DEFB112 6.4e-08 2345 379214 381559 Paroxysmal supraventricular tachycardia 0 427.11 1.0054 circulatory system 12 18999030 C A rs73066208 PLEKHA5 6.4e-08 6660 396439 403099 Bacterial pneumonia 0 480.1 1.0054 respiratory 18 70264026 TA T rs11314461 SOCS6 6.4e-08 113 396443 396556 Gingivitis 0 523.1 1.0601 digestive 15 42651382 G C rs193284586 STARD9 6.4e-08 309 189131 189440 Premenopausal menorrhagia 0 627.4 1.0224 genitourinary 21 31877852 G A rs776185304 HUNK 6.4e-08 208 406081 406289 Congenital deformities of feet 0 755.1 1.0567 congenital anomalies 7 122245939 A C rs1249166922 FEZF1 6.5e-08 4591 401095 405686 Dizziness and giddiness (Light-headedness and vertigo) 0 386.9 1.0082 sense organs 18 45531976 C A rs545669451 SLC14A2 6.5e-08 1216 374656 375872 Other acute and subacute forms of ischemic heart disease 0 411.9 1.0 circulatory system 6 88927199 T C rs867166711 RNGTT 6.5e-08 60 403885 403945 Other cardiomyopathy 0 425.8 1.0082 circulatory system 4 94329196 C T rs1282510455 HPGDS 6.5e-08 694 213273 213967 Other specified benign mammary dysplasias 0 610.8 0.97444 genitourinary 15 50750249 G A rs756662002 SPPL2A 6.5e-08 1132 212251 213383 Missed abortion/Hydatidiform mole 0 634.1 1.0 pregnancy complications 12 29731437 C T rs558023940 TMTC1 6.6e-08 1131 392385 393516 Nerve root and plexus disorders 0 353 1.0 neurological 20 8271377 C G rs553181423 PLCB1 6.6e-08 3396 376450 379846 Other disorders of stomach and duodenum 0 537 1.0 digestive 1 210431751 C T rs147458134 HHAT 6.6e-08 74 406709 406783 Traumatic and surgical subcutaneous emphysema 0 958.2 1.0375 injuries & poisonings 11 93366018 A G rs186591385 DEUP1 6.7e-08 208 218077 218285 Polycystic ovaries 0 256.4 1.0313 endocrine/metabolic 1 47748519 T A rs117237002 TRABD2B 6.7e-08 128 399782 399910 Polydipsia 0 276.8 1.0635 endocrine/metabolic 4 151315850 T C rs577583451 SH3D19 6.7e-08 326 405230 405556 Other specified disorders of breast 0 613.8 1.0195 genitourinary 7 91294521 T C rs905282086 FZD1 6.8e-08 127 406672 406799 Helminthiases 0 134 1.0601 infectious diseases 6 136402466 C T rs917895566 MAP7 6.8e-08 1230 401593 402823 Diseases and other conditions of the tongue 0 529 1.0 digestive 7 155180657 A AT rs1171954995 HTR5A 6.8e-08 1531 395835 397366 Nephritis; nephrosis; renal sclerosis 0 580 1.0054 genitourinary 6 100102925 A AT MCHR2 6.8e-08 726 210805 211531 Noninflammatory disorders of ovary, fallopian tube, and broad ligament 0 619.1 0.97444 genitourinary 17 31042381 G A rs77347544 RNF135 6.8e-08 9023 378896 387919 Osteoarthrosis, localized, primary 0 740.11 1.0313 musculoskeletal 6 145165786 G T rs778284759 EPM2A 6.9e-08 652 398252 398904 Intestinal infection due to C. difficile 0 008.52 0.97444 infectious diseases 15 71074436 GA G rs1280594537 LRRC49 6.9e-08 177 388394 388571 Other vitamin B12 deficiency anemia 0 281.12 1.0669 hematopoietic 4 19725860 C A rs1048194442 SLIT2 6.9e-08 636 399772 400408 Hemorrhage from gastrointestinal ulcer 0 531.1 0.97444 digestive 2 58911179 C G rs191964029 FANCL 6.9e-08 4194 385688 389882 Other disorders of intestine 0 569 1.0054 digestive 5 91733005 G A rs191110970 ARRDC3 6.9e-08 2345 402141 404486 Scar conditions and fibrosis of skin 0 701.2 1.0 dermatologic 10 69165816 C A rs1327397752 VPS26A 6.9e-08 103 377181 377284 Bursitis disorders 0 727.2 1.0567 musculoskeletal 17 49692998 A G rs937752885 SLC35B1 7e-08 1163 396444 397607 Periodontitis (acute or chronic) 0 523.3 1.0 digestive 10 71563274 G T rs114687625 CDH23 7e-08 1355 386071 387426 Fracture of vertebral column without mention of spinal cord injury 0 805 1.0054 injuries & poisonings 14 52686643 C T rs149040667 ERO1A 7.1e-08 1400 217129 218529 Problems associated with amniotic cavity and membranes 0 653 1.0 pregnancy complications 3 127253583 C T rs565561072 PRR20G 7.2e-08 163 401998 402161 Insomnia 0 327.4 1.0704 neurological X 79669589 C A ITM2A 7.2e-08 207 405229 405436 Breast disorder NOS 0 613.9 1.0567 genitourinary X 56939888 G A rs189409346 SPIN3 7.2e-08 454 218959 219413 Congenital anomalies of female genital organs 0 751.11 1.0 congenital anomalies 14 84702409 C G rs544298206 FLRT2 7.3e-08 70 400600 400670 Other persistent mental disorders due to conditions classified elsewhere 0 290.3 1.0054 mental disorders 5 60404456 A G rs1249372248 PDE4D 7.3e-08 4674 388550 393224 Septal Deviations/Turbinate Hypertrophy 0 470 1.0082 respiratory 3 176072818 A C rs921821926 NAALADL2 7.3e-08 68 219709 219777 Infectious and parasitic complications affecting pregnancy 0 647 1.0195 pregnancy complications 5 2270760 T C rs72712976 IRX4 7.3e-08 984 400950 401934 Dyschromia and Vitiligo 0 694 1.0 dermatologic 19 52062836 T C rs78988733 ZNF432 7.4e-08 66 407136 407202 Effects of heat, cold and air pressure 0 1014 1.0224 injuries & poisonings 5 179152427 G A rs759260638 ADAMTS2 7.4e-08 74 404551 404625 Dermatophytosis of nail 0 110.11 1.0283 infectious diseases 21 40728034 C G rs779840291 DSCAM 7.4e-08 142 403660 403802 Hypoparathyroidism 0 252.2 1.0704 endocrine/metabolic 6 153474162 C T rs143164316 RGS17 7.4e-08 53 388395 388448 Deficiency anemias 0 281.9 0.97444 hematopoietic 18 52807769 T A rs527936423 DCC 7.4e-08 86 396051 396137 Keratoconus 0 364.41 1.0469 sense organs 16 16592986 T TA NPIPA7 7.4e-08 425 399772 400197 Peptic ulcer, site unspecified 0 531.4 0.97444 digestive 13 50912246 A G rs553484857 RNASEH2B 7.4e-08 3351 395834 399185 Other disorders of the kidney and ureters 0 586 1.0 genitourinary 18 62190828 C A rs868042134 RELCH 7.5e-08 106 406672 406778 Intestinal helminthiases 0 134.1 1.0567 infectious diseases 2 177226502 ACTC A rs1206672573 NFE2L2 7.6e-08 183 388395 388578 Folate-deficiency anemia 0 281.13 1.0635 hematopoietic 2 162152086 T C rs1022695334 GCG 7.6e-08 63 404523 404586 Congenital factor VIII disorder 0 286.13 0.95116 hematopoietic 19 33405479 G A rs1247910353 PEPD 7.6e-08 75 404523 404598 Secondary thrombocytopenia 0 287.32 1.0344 hematopoietic 4 85325136 G C rs191323996 ARHGAP24 7.6e-08 656 395581 396237 Pneumonitis due to inhalation of food or vomitus 0 501 0.97444 respiratory 4 91170933 T C rs554148338 CCSER1 7.6e-08 907 395835 396742 Stricture/obstruction of ureter 0 586.4 0.97444 genitourinary 8 140041205 T C rs567221460 TRAPPC9 7.6e-08 1871 405330 407201 Symptoms involving nervous and musculoskeletal systems 0 781 1.011 symptoms 11 102744790 C T rs1007521067 MMP8 7.7e-08 537 333378 333915 Ulcerative colitis (chronic) 0 555.21 0.97444 digestive 2 128224858 G A rs769187388 HS6ST1 7.8e-08 5059 390235 395294 Spondylosis without myelopathy 0 721.1 1.0195 musculoskeletal 7 2966440 A C rs759674391 CARD11 7.9e-08 2909 378357 381266 Cystitis 0 592.1 1.0027 genitourinary 9 3699821 A G rs191352006 GLIS3 8e-08 216 393432 393648 Essential tremor 0 333.1 1.0601 neurological 12 69333346 C A rs879616203 LYZ 8e-08 389 393433 393822 Other conditions of brain, NOS 0 348.9 1.0054 neurological 2 173418948 T C rs367558404 CDCA7 8e-08 1296 403146 404442 Other disorders of tympanic membrane 0 384 1.0082 sense organs 16 53773852 A G rs17817288 FTO 8e-08 3260 385683 388943 Other disorders of peritoneum 0 568 1.0027 digestive 15 97035731 C T rs575600482 NR2F2 8e-08 109 407093 407202 Other perinatal conditions of fetus or newborn 0 656 1.0469 pregnancy complications 2 172305756 A G rs746838587 ITGA6 8e-08 332 405003 405335 Other specified congenital anomalies of kidney 0 751.22 1.0224 congenital anomalies 6 168554886 C T rs767435594 SMOC2 8.1e-08 345 219743 220088 Multiple gestation 0 651 1.0054 pregnancy complications 3 190376066 G A rs532354896 CLDN16 8.1e-08 780 400950 401730 Other dyschromia 0 694.2 0.97444 dermatologic 15 34969069 A G rs10152363 AQR 8.1e-08 1613 390236 391849 Other unspecified back disorders 0 724.9 1.011 musculoskeletal 18 62965941 G A rs183470102 PHLPP1 8.2e-08 272 404552 404824 Mycoses 0 117 1.0344 infectious diseases 7 51642218 C T rs756550658 COBL 8.2e-08 2075 193708 195783 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] 0 180.3 1.0082 neoplasms X 154709509 A G rs111531522 GAB3 8.2e-08 52 405784 405836 Lipoprotein disorders 0 277.51 1.0 endocrine/metabolic 8 22581514 C T rs748585448 PDLIM2 8.2e-08 1919 218169 220088 Normal delivery 0 650 1.0054 pregnancy complications 2 212018702 C A rs768202221 ERBB4 8.2e-08 596 395973 396569 Cellulitis and abscess of trunk 0 681.7 0.97444 dermatologic 19 53625775 C A rs544490875 DPRX 8.4e-08 393 406436 406829 Acute pain 0 338.1 1.0054 neurological X 94527026 C T rs781637337 FAM133A 8.4e-08 1276 397137 398413 Late effects of cerebrovascular disease 0 433.8 1.0 circulatory system 8 127715591 G A rs1002103757 MYC 8.4e-08 5214 212254 217468 Miscarriage; stillbirth 0 634 1.0 pregnancy complications 1 99293038 G C rs765013723 PLPPR4 8.4e-08 3504 398899 402403 Open wounds of head; neck; and trunk 0 870 1.0027 injuries & poisonings 7 146707922 A T rs185117647 CNTNAP2 8.5e-08 3802 189128 192930 Irregular menstrual bleeding 0 626.14 1.0 genitourinary X 112091199 C T rs779229794 TRPC5 8.6e-08 1881 397139 399020 Intracranial hemorrhage 0 430 1.0082 circulatory system 21 33773402 A C rs75672446 AP000311.1,ITSN1 8.6e-08 91 398898 398989 Open wound of finger(s) 0 871.2 0.97444 injuries & poisonings 4 24189596 T C rs563132974 PPARGC1A 8.7e-08 255 406947 407202 Crushing injury 0 1006 1.0437 injuries & poisonings 3 130402437 G A rs867759855 COL6A5 8.8e-08 764 397139 397903 Intracerebral hemorrhage 0 430.2 0.97444 circulatory system 6 93238093 A G rs985485184 EPHA7 9.1e-08 435 388396 388831 Aplastic anemia 0 284 1.0 hematopoietic 2 52627896 T C rs376775733 ASB3 9.2e-08 2971 378356 381327 Cystitis and urethritis 0 592 1.0 genitourinary 16 58143411 C T rs191815313 CFAP20 9.2e-08 512 390232 390744 Displacement of intervertebral disc 0 722.1 0.97444 musculoskeletal X 68013042 A G rs5965492 OPHN1 9.2e-08 597 378890 379487 Osteoarthrosis, generalized 0 740.2 0.97444 musculoskeletal 7 12673471 A C rs567409239 SCIN 9.3e-08 105 407097 407202 Late effect 0 1012 1.0437 injuries & poisonings 16 6887131 A G rs540099036 RBFOX1 9.3e-08 196 404740 404936 Acute sinusitis 0 464 1.0635 respiratory 17 58358524 G T rs2526374 AC004687.2,RNF43 9.4e-08 1803 395582 397385 Respiratory insufficiency 0 509.2 1.0082 respiratory 8 61453439 G C rs1212120652 CLVS1 9.4e-08 849 400114 400963 Hypertrophy of breast (Gynecomastia) 0 612.2 0.97444 genitourinary 1 244786659 C A rs1047255469 COX20 9.5e-08 1299 386070 387369 Fracture of unspecified bones 0 809 1.0027 injuries & poisonings 2 232685848 G A rs1301612805 EFHD1 9.7e-08 814 399566 400380 Osteopenia or other disorder of bone and cartilage 0 743.9 0.97444 musculoskeletal 16 29611248 C G rs1039401642 SPN 9.8e-08 1658 393013 394671 Functional disorders of bladder 0 596.5 1.011 genitourinary 22 37250057 C T rs768924087 RAC2 9.9e-08 887 400114 401001 Breast conditions, congenital or relating to hormones 0 612 1.0 genitourinary 4 67172847 G T rs1157691302 CENPC 1e-07 2171 193708 195879 Cervical cancer and dysplasia 0 180 1.0082 neoplasms 1 80943363 G GCA rs1289300526 ADGRL2 1e-07 265 405669 405934 Benign neoplasm of thyroid glands 0 226 1.0313 neoplasms 8 125598554 G A rs1041805560 TRIB1 1e-07 379 406436 406815 Chronic pain 0 338.2 1.0054 neurological 13 77508443 T C rs777613818 SCEL 1e-07 846 395156 396002 Retinal vascular changes and abnomalities 0 362.4 0.97444 sense organs 1 231043138 G T rs1168437125 FAM89A 1e-07 3939 333382 337321 Intestinal obstruction without mention of hernia 0 560 1.0054 digestive 5 91955063 C T rs148130954 ARRDC3 1e-07 109 189130 189239 Absent or infrequent menstruation 0 626.11 1.0635 genitourinary 2 78621783 A C rs1025705183 REG3G 1e-07 67 390234 390301 Postlaminectomy syndrome 0 722.8 1.0054 musculoskeletal 8 29516563 C G rs746722557 DUSP4 1e-07 327 406644 406971 Nervous system congenital anomalies 0 752 1.0224 congenital anomalies 6 14155180 T C rs139906211 CD83 1e-07 60 406232 406292 Chromosomal anomalies 0 758.1 1.0027 congenital anomalies 2 101529219 C T rs1703849 RFX8 1e-07 764 386071 386835 Fracture of patella 0 800.4 0.97444 injuries & poisonings 1 77407729 C T rs769875307 AK5 1e-07 3026 404176 407202 Sepsis and SIRS 0 994 1.0 injuries & poisonings 1 77407729 C T rs769875307 AK5 1e-07 3026 404176 407202 Sepsis 0 994.2 1.0 injuries & poisonings 15 26063781 T A rs117320127 ATP10A 1.1e-07 1203 405079 406282 Disorders of calcium/phosphorus metabolism 0 275.5 1.0027 endocrine/metabolic 11 5960118 T G rs771422836 OR56A5 1.1e-07 113 363984 364097 Posttraumatic stress disorder 0 300.9 1.0635 mental disorders X 120786123 G T rs187741876 CT47B1 1.1e-07 244 393433 393677 Anterior horn cell disease 0 334.2 1.0501 neurological 6 23621596 A G rs373318336 NRSN1 1.1e-07 265 393433 393698 Disorders of the autonomic nervous system 0 337 1.0406 neurological 4 169557940 GTAAA G rs560559215 NEK1 1.1e-07 125 399529 399654 Optic neuritis/neuropathy 0 377.3 1.0635 sense organs 8 128544235 G A rs545215668 MYC 1.1e-07 1492 379216 380708 Right bundle branch block 0 426.31 1.0 circulatory system 1 184588888 G A rs573981278 C1orf21 1.1e-07 792 396439 397231 Bronchopneumonia and lung abscess 0 480.5 0.97444 respiratory 10 85180521 C G rs903179296 GRID1 1.1e-07 61 395582 395643 Other pulmonary inflamation or edema 0 505 1.011 respiratory 18 57221341 C T rs770279662 BOD1L2 1.1e-07 1643 333377 335020 Abnormal findings on exam of gastrointestinal tract/ abdominal area 0 564.8 1.0082 digestive X 127550117 A G rs765809530 ACTRT1 1.1e-07 80 395834 395914 Vascular disorders of kidney/hypertrophy 0 586.3 1.0344 genitourinary 16 13962991 G A rs143217048 ERCC4 1.1e-07 367 395835 396202 Kidney replaced by transpant 0 587 1.011 genitourinary X 31092964 A G rs765957298 DMD 1.1e-07 234 169004 169238 Acute prostatitis 0 601.11 1.0501 genitourinary 8 1452000 C T rs1389273423 DLGAP2 1.1e-07 106 401683 401789 Changes in skin texture 0 687.3 1.0567 dermatologic 4 151785128 G A rs560709895 GATB 1.1e-07 106 406081 406187 Congenital hip dysplasia and deformity 0 755.61 1.0567 congenital anomalies 10 82727432 G A rs989041840 NRG3 1.1e-07 171 407031 407202 Hypothermia/Chills 0 780 1.0635 symptoms 12 97166704 C T rs1050360678 NEDD1 1.1e-07 102 407046 407148 Cardiogenic shock 0 797.1 1.0601 symptoms 14 95142595 A G rs555733176 DICER1 1.2e-07 57 405057 405114 Cancer of of nasal cavities 0 149.9 1.0 neoplasms 19 29066404 T C rs753490232 UQCRFS1 1.2e-07 1549 368850 370399 Secondary malignant neoplasm of digestive systems 0 198.3 1.0082 neoplasms 2 22143668 A T rs1038217253 TDRD15 1.2e-07 837 400600 401437 Other specified nonpsychotic and/or transient mental disorders 0 291 0.97444 mental disorders 12 3813268 G A rs571841301 PARP11 1.2e-07 840 363984 364824 Schizophrenia and other psychotic disorders 0 295 0.97444 mental disorders 18 25527505 G A rs866391472 ZNF521 1.2e-07 250 396052 396302 Progressive myopia 0 360.2 1.0437 sense organs 15 39878712 A G rs769870693 GPR176 1.2e-07 1958 383447 385405 Hematemesis 0 578.1 1.0082 digestive 3 66850058 G A rs569561383 KBTBD8 1.2e-07 2819 167468 170287 Other disorders of male genital organs 0 608 1.0 genitourinary 3 64949280 C T rs751389828 ADAMTS9 1.2e-07 4758 189127 193885 Ovarian cyst 0 628 1.0027 genitourinary 3 195056376 G A rs575743515 XXYLT1 1.2e-07 76 400627 400703 Other specified diseases of hair and hair follicles 0 704.8 1.0375 dermatologic 1 223152856 T C rs908047640 TLR5 1.2e-07 327 364270 364597 Pyogenic arthritis 0 711.1 1.0224 musculoskeletal 14 34127318 G A rs145643129 EGLN3 1.3e-07 287 389744 390031 Thyroiditis 0 245 1.0283 endocrine/metabolic 9 15307748 A C rs72702749 TTC39B 1.3e-07 515 399655 400170 Diseases of spleen 0 289.5 0.97444 hematopoietic 16 77563528 C T rs759702309 ADAMTS18 1.3e-07 4022 383301 387323 Frequency of urination and polyuria 0 599.5 1.0054 genitourinary 20 41158572 T C rs760848567 PLCG1 1.3e-07 105 383297 383402 Oliguria and anuria 0 599.6 1.0534 genitourinary 14 92740252 AAAAG A LGMN 1.3e-07 169 398897 399066 Complication of amputation stump 0 874 1.0704 injuries & poisonings 22 31511895 G C rs1024123530 DRG1,SFI1 1.5e-07 188 368847 369035 Secondary malignant neoplasm of skin 0 198.7 1.0601 neoplasms 2 79099089 T C rs283895 REG1B 1.5e-07 51 404730 404781 Cachexia 0 260.1 0.97444 endocrine/metabolic 11 109192516 G A rs867302648 C11orf87 1.5e-07 56 399529 399585 Optic atrophy 0 377.1 1.0 sense organs 3 68304604 T G TAFA1 1.5e-07 1181 376448 377629 Acute gastritis 0 535.1 1.0 digestive 2 231788027 CTT C rs780041937 COPS7B 1.5e-07 752 210934 211686 Cyst or abscess of Bartholin's gland 0 614.53 0.97444 genitourinary 2 81257687 A G rs924122940 CTNNA2 1.5e-07 679 207908 208587 Vaginal enterocele, congenital or acquired 0 618.6 0.97444 genitourinary 4 56102885 G T rs1055988692 CRACD 1.5e-07 4061 398899 402960 Open wounds of extremities 0 871 1.0 injuries & poisonings 17 74315953 T C rs767545919 DNAI2 1.5e-07 58 380139 380197 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs 0 976 1.0027 injuries & poisonings 5 95638932 G A rs76861702 RFESD 1.6e-07 2769 401603 404372 Viral infection 0 079 1.0 infectious diseases 10 33319844 C T rs533899752 NRP1 1.6e-07 193 219789 219982 Diabetes or abnormal glucose tolerance complicating pregnancy 0 649.1 1.0054 pregnancy complications 9 24337351 T C rs997952753 IZUMO3 1.6e-07 54 400908 400962 Villonodular synovitis 0 741.6 0.95116 musculoskeletal 10 62025165 G A rs534600258 ARID5B 1.7e-07 2728 392083 394811 E. coli 0 041.4 1.0 infectious diseases 13 104355808 A T rs768118685 DAOA 1.8e-07 1140 393433 394573 Other cerebral degenerations 0 331 1.0 neurological 6 169542249 A G rs752685737 AL031315.1,WDR27 1.8e-07 120 376446 376566 Gastritis and duodenitis, NOS 0 535.9 0.91006 digestive 2 172429772 G A rs1438757299 ITGA6 1.9e-07 58 371432 371490 Hyperglyceridemia 0 272.12 1.0 endocrine/metabolic 9 14623227 G A rs777524123 ZDHHC21 1.9e-07 72 393432 393504 Peripheral autonomic neuropathy 0 337.1 1.0224 neurological 3 33199474 C T rs900730421 SUSD5 1.9e-07 113 403885 403998 Chronic pericarditis 0 420.22 1.0704 circulatory system 3 22248765 G A rs374626027 ZNF385D 2e-07 637 403660 404297 Disorders of adrenal glands 0 255 0.97444 endocrine/metabolic 6 16457494 C T rs114854973 ATXN1 2e-07 274 219710 219984 Infections of genitourinary tract during pregnancy 0 647.1 0.97444 pregnancy complications 4 131607793 A G rs193264401 PCDH10 2.2e-07 3316 393016 396332 Urethral stricture (not specified as infectious) 0 597.1 1.0027 genitourinary 16 22761387 C T rs767315732 HS3ST2 2.5e-07 341 393433 393774 Other and unspecified disorders of the nervous system 0 349 1.0195 neurological 22 23613074 C T rs998918540 DRICH1 4.1e-07 149 403660 403809 Other endocrine disorders 0 259 0.81567 endocrine/metabolic X 113837084 TATATA T rs782569971 HTR2C 4.7e-07 165 403885 404050 Other hypertrophic cardiomyopathy 0 425.12 0.51319 circulatory system 13 104427129 G A rs7984360 DAOA 9e-06 310 363984 364294 Suicide or self-inflicted injury 0 297.2 0.65569 mental disorders