About This PheWeb : Freeze 6

This PheWeb includes genome-wide associations for EHR-derived ICD billing codes from the multi-ancestry cohort in Precision Health MGI. Phenotypes were classified into broad PheWAS codes using the PheWAS R package available from Vanderbilt. All individuals were imputed using TOPMed. Analyses on binary outcomes were conducted using SAIGE (a generalized mixed model association test that uses the saddlepoint approximation to account for case-control imbalance), adjusting for genetic relatedness, sex, age, chip version, and the first 20 principal components. More information about the Freeze 6 Pheweb can be found here

Older Version of Pheweb with Freeze 3 data is available at : here

All positions are on GRCh38.

This site was built with PheWeb version 1.3.15.

If you would like to request access to this Pheweb, report a bug, or make a suggestion, please email mgi.pheweb@umich.edu.